Grants

AgricultureCommunity Developmenteconomic_development

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Department of Commerce Rural Economic Development Grants

NC Department of Commerce

The NC Department of Commerce funds rural economic development initiatives, community infrastructure, business recruitment, and job creation programs targeting economically distressed counties across North Carolina.

$50K – $2M

economic_developmentCommunity Developmentworkforce

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Department of Environmental Quality Environmental Grants

NC Department of Environmental Quality

NCDEQ provides grants to municipalities, nonprofits, and community organizations for water quality improvement, clean energy projects, environmental restoration, and resilience planning throughout North Carolina.

$25K – $3M

EnvironmentalinfrastructureCommunity Development

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Department of Health and Human Services Community Grants

NC Department of Health and Human Services

NCDHHS funds nonprofits, health organizations, and community agencies providing mental health, substance abuse, developmental disability, public health, and social services to vulnerable North Carolinians.

$50K – $2M

HealthEquity & AccessCommunity Development+1

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Department of Public Instruction Competitive Grants

NC Department of Public Instruction

The NC Department of Public Instruction administers competitive grants to support K-12 public schools and districts in implementing innovative instructional programs, improving literacy and math outcomes, and expanding career and technical education.

$25K – $1M

EducationEquity & Accessyouth_development

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Department of Public Safety Grants

NC Department of Public Safety

NCDPS administers federal and state grants to local law enforcement, fire departments, emergency management agencies, and nonprofits for public safety, crime prevention, juvenile justice, and disaster preparedness across North Carolina.

$10K – $1M

Community Developmentinfrastructureyouth_development

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC DEQ Environmental Grants

NC Dept of Environmental Quality

Grants for water quality, land conservation, and clean energy projects in North Carolina.

$10K – $500K

environmentclean_energy

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC EDPNC Economic Incentives

Economic Development Partnership of North Carolina

Administers Job Development Investment Grants (JDIG), One NC Fund grants, and workforce development programs for North Carolina businesses.

$50K – $5M

economic developmentjob creationworkforce

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Education Lottery Scholarship

financial aidscholarshipshigher education

North Carolina State Education Assistance Authority

State scholarship and financial aid program administered by North Carolina State Education Assistance Authority for NC students and educational institutions.

$500 – $7K

2026-10-01

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Film Office Grants & Rebates

NC Film Office

Rebates and grants for film, TV, and commercial production in North Carolina.

$5K – $100K

filmtourism

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC First in Future Innovation Grants

NC Dept of Commerce — Science & Technology

Grants for small business innovation, technology commercialization, and SBIR matching.

$10K – $500K

technologyinnovation

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Housing Finance Agency Affordable Housing Grants

NC Housing Finance Agency

NCHFA administers HOME, LIHTC, and other housing programs providing grants and financing to nonprofits, developers, and local governments for affordable rental and homeownership housing throughout North Carolina.

$100K – $5M

HousingCommunity DevelopmentEquity & Access

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Office of Rural Health Rural Health Grants

NC Office of Rural Health

The NC Office of Rural Health provides grants to rural health clinics, safety net providers, and community organizations to improve access to healthcare, address health disparities, and strengthen rural health infrastructure in underserved North Carolina communities.

$25K – $500K

HealthEquity & AccessCommunity Development

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Pre-K Program Grants

early childhoodpre-kschool readiness

NC Division of Child Development and Early Education

Early childhood education grants supporting pre-K programs, childcare quality improvement, and school readiness initiatives in NC.

$30K – $400K

2026-06-30

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC SHPO Historic Preservation Grants

NC State Historic Preservation Office

Grants for historic property surveys, National Register nominations, and rehabilitation projects.

$5K – $100K

historic_preservation

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC STEM Center Education Grants

STEMscience educationtechnology education

NC Department of Public Instruction

STEM education initiative grants for NC to expand science, technology, engineering, and mathematics programs in K-12 and postsecondary institutions.

$10K – $150K

2026-10-01

Free to search & build · $99 one-time to unlock the application pack · No subscription

NC Veterans Affairs Grants

NC Dept of Military & Veterans Affairs

Grants for veteran employment programs, housing assistance, and mental health services.

$5K – $50K

veterans

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)

National Institutes of Health

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite feasibility trials is expected to be justified by sufficient preliminary data from previous single site feasibility or acceptability trial(s) or the published literature. The data collected should be used to fill gaps in scientific knowledge and be necessary to develop a competitive fully powered multisite clinical trial that has the potential to make a significant impact on public health.

Up to $350K

2026-11-17

Health

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Multi-Site Feasibility Clinical Trials of Mind and Body Interventions (R01 Clinical Trial Required)

National Institutes of Health

This notice of funding opportunity (NOFO) invites applications for investigator-initiated clinical trials of complementary and integrative health approaches with physical and/or psychological therapeutic inputs (often called mind and body interventions) in NCCIH-designated areas of high research priority. Applications submitted under this NOFO are expected to propose a multisite feasibility clinical trial that will provide new information that is scientifically necessary for the planning and conduct of a subsequent clinical efficacy or effectiveness study, pragmatic trial, or dissemination and implementation trial within NCCIHs mission. NCCIH expects that applications to this NOFO will describe the planned future clinical trial and in so doing demonstrate that the proposed (R01) research is scientifically necessary to design or plan the subsequent fully powered, full-scale clinical trial. Under this R01, the data collected should be used to fill gaps in scientific knowledge, including, but not limited to the following: assessing whether the intervention can be delivered with fidelity across sites; demonstrating feasibility of recruitment, accrual, and randomization of participants across sites; demonstrating participant adherence to the intervention, as well as retention of participants throughout the study across sites; refining and assessing the feasibility of protocolized multimodal interventions, and/or demonstrating feasibility of data collection across sites in preparation for a future fully powered, multisite efficacy or effectiveness trial. The need for multisite feasibility trials is expected to be justified by sufficient preliminary data from previous single site feasibility or acceptability trial(s) or the published literature. The data collected should be used to fill gaps in scientific knowledge and be necessary to develop a competitive fully powered multisite clinical trial that has the potential to make a significant impact on public health.

Up to $350K

2026-11-17

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

Up to $1.1M

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Natural Product Early Phase Clinical Trial Award (R33 Clinical Trial Required)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to 3 years support for studies to replicate the impact of the natural product on target engagement when used by humans, and assess whether there is an association between the degree of the impact on target engagement and functional or clinical outcomes in a patient population. Applications are encouraged to design studies to determine how to optimize the impact of the natural product on target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to engage the same target; or study the impact of the natural product in a target population that is more responsive. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This R33 funding mechanism is intended to accelerate the translation of emerging basic science findings about natural products into early-stage clinical testing to determine whether continued clinical research is warranted. This NOFO will not support efficacy or effectiveness trials, nor will

Up to $1.1M

Health

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Natural Product Early Phase Clinical Trial Phased Innovation Award (R61/R33 Clinical Trial Required)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated, early phase, clinical trials of natural products (i.e., botanicals, probiotics, and products marketed as dietary supplements), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. Under this NOFO, trials must be designed so that results, whether positive or negative, will provide information of high scientific utility and will support decisions about further development or testing of the natural product. This NOFO will provide up to three years (R61 phase) of support for milestone-driven testing of pharmacokinetics, bioavailability, and assessment of the natural products effect (i.e., measure of mechanism of action) when used by humans on a specified target measure. If milestones in the R61 phase are achieved, up to 3 years of additional support (R33 phase) may be awarded to replicate the impact of the natural product on target engagement(s) when used by humans and assess whether there is an association between the degree of the impact on the target engagement and clinical outcomes in a participant population. Applications are encouraged to design R33 studies to determine how to optimize the impact of the natural product on the target engagement by optimizing the delivery of the natural product through examination of different doses or formulations. In addition, applications can be designed to combine the natural product with another treatment approach that is known to impact the same target engagement measure; or study the impact of the natural product in a population that is more responsive,

Up to $350K

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived. Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or formulation of a given natural product for use in a future multi-site efficacy trial; or determine which patient phenotypes will be responders versus non-responders to the natural product to inform inclusion/exclusion criteria of a future efficacy trial. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This NOFO will not support single-site or multi-site efficacy or effectiveness trials, nor will it support trials to test natural products for the treatment or prevention of cancer. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NO

Free to search & build · $99 one-time to unlock the application pack · No subscription

NCCIH Natural Product Mid Phase Clinical Trial (R01 Clinical Trial Required)

National Institutes of Health

This Notice of Funding Opportunity (NOFO) encourages applications for investigator-initiated mid-phase clinical trials of natural products(i.e., botanicals, dietary supplements, and probiotics), which have a strong scientific premise to justify further clinical testing. For this NOFO, natural products include promising nutritional regimens that standardize the amount of a specific naturally occurring nutritional compound (e.g., omega-3 fatty acids, anthocyanidins, or polyphenols) and have compelling preliminary evidence. All applications submitted under this NOFO must be supported by sufficient preliminary data demonstrating bioavailability (if applicable) and documentation that the natural product produces a reproducible and measurable impact on target engagement (i.e., measure of the mechanism of action). Only in cases when it is not possible/practical to measure target engagement in the patient population of interest or when there is a fundamental understanding of the products mechanism of action will this preliminary data requirement be waived. Applications submitted to this NOFO should propose a mid-phase clinical trial to do the following: determine the optimal dose or formulation of a given natural product for use in a future multi-site efficacy trial; or determine which patient phenotypes will be responders versus non-responders to the natural product to inform inclusion/exclusion criteria of a future efficacy trial. Clinical trials submitted under this NOFO are expected to be hypothesis based, milestone-driven, and directly related to the research priorities and mission of NCCIH. This NOFO will not support single-site or multi-site efficacy or effectiveness trials, nor will it support trials to test natural products for the treatment or prevention of cancer. Applicants are encouraged to contact the appropriate NCCIH Scientific/Research contact for the area of science for which they are planning to develop an application prior to submitting to this NO