Grants
23,966 grants found
Activate Arts! Beacon Hill
openCommunity Dance Program
The Community Dance group will be hosting various " Fair Days" at the Centilia Cultural Center located at El Centro de la Raza 2524 16th Ave South. The Fair days will happen August 9 and September 13. The purpose of this project is to celebrate the rich diversity of the Beacon Hill neighborhood by highlighting various cultural activities and dance that reflect ethnic groups such as Latino, Asian, East African etc. The event is free and open to the public.
Activating Rainier Beach Urban Farm and Wetlands
openSeattle Tilth
Add a children’s learning garden, rain gardens, and educational signage; equip the community farm stand, kitchen, and greenhouses; and host a community-led celebration. The Farm serves as a community space for organic farming, food distribution, education, and community building.
Active Media Services Capital
openEDF 13-14 Local
Active Media Services Capital
ActiveVistas
openPowerful Voices
Provide a 12-week employment program to prepare 13 low-income girls of color, ages 14 to 18, to utilize technology as a civic engagement tool. Participants work with mentors to develop multimedia presentations on social justice topics impacting their lives and neighborhoods and present them at the Girlvolution Conference.
Activity-dependent cell survival in the adult somatosensory dorsal horn: Implications for sensorimotor behaviors during aging
openNIA - National Institute on Aging
Project Summary/Abstract The somatosensory dorsal horn comprises an array of neuronal populations that receive sensory information from the skin. In recent years, the development of transcriptomic and intersectional genetic tools has allowed the characterization of these populations in young adult animals with respect to their distinct molecular identities and functional roles in the processing and transmission of touch, pain and itch information. Preliminary data indicate that the survival of neurons in the dorsal horn of adult mice is dependent on excitatory input from touch receptors in the skin. This has implications for the processing of somatosensory information during aging, in which the transmission of touch information is impaired by demyelination and by the loss of mechanosensory end organs including Merkel cells (Feng et al., 2018). Chronic silencing Merkel cells in young adult Atoh1CreERT2; Piezo2f/f mice results in the apoptotic loss of excitatory and inhibitory dorsal horn neurons by 20-25%, with some molecularly defined populations being highly susceptible to cell death and others being resistant. A similar pattern of neuronal cell loss by apoptosis is detected in the dorsal horn of 2-year-old mice. The objective of this proposal is to characterize activity-dependent changes to the cellular composition of the spinal dorsal horn during aging and to determine the functional consequences of dorsal horn remodeling for the execution of sensorimotor behaviors as animals age. These experiments will (1) selectively perturb activity in different classes of cutaneous afferent to identify inputs that support cell survival in adult mice; (2) identify dorsal horn populations, defined by molecular profile, that are maintained by input from the periphery; (3) identify molecularly defined dorsal horn populations that are reduced in size during aging; (4) test the hypothesis that the reduction in the size of the neuronal population marked by expression of Cck and Sst that occurs following the loss of input from Merkel cells during aging impairs the execution of skilled locomotor and other sensorimotor behaviors; Cck+/Sst+ neurons are proposed to relay cutaneous tactile information to ventral horn motor circuits. Activity-dependent remodeling of the cellular landscape of the dorsal horn has broad implications for the processing of touch, pain and itch information during aging, as well as in conditions in which peripheral input is impaired, such as the peripheral neuropathies that arise from diabetes mellitus and chemotherapy treatment. This proposal will advance our understanding of how somatosensory processing changes across the lifespan and will determine the contribution of these changes to age-related sensorimotor dysfunction. Furthermore, it will likely inform therapeutic strategies for the treatment of somatosensory and sensorimotor disorders in older populations.
Actors Theatre Workshop, Inc.
openNYC Department of Cultural Affairs
Actors Theatre Workshop, Inc.
Actors' Fund of America
openNYC Department of Cultural Affairs
Actors' Fund of America
ACTUARIAL AND RELATED CONSULTING SERVICES FOR SELF-INSURED WORKDER'S COMPENSATION AND OTHER LIABILITY CLAIMS
openAON RISK CONSULTANTS INC
Financial and Insurance Services
ACTUARIAL CONSULTATION AND ADVISORY SERVICES
openCAVANAUGH MACDONALD CONSULTING LLC
Management and Business Professionals and Administrative Services
ACURA INC(INCREASE)
openAcura Inc.
Engineering and Research and Technology Based Services
ADA Compliance Various Parks
openNew Britain
ADA Compliance Various Parks
ADA Curb Cuts
openCity of Brunswick
ADA Curb Cuts
ADA Curb Ramps
openTown of Emmitsburg
ADA Curb Ramps
ADA Curb Ramps
openFrederick County, Maryland
ADA Curb Ramps
ADA Curb Ramps
openCity of Westminster
ADA Curb Ramps
ADA Improvements
openTown of Vienna
ADA Improvements
ADA Improvements
openTown of Mardella Springs
ADA Improvements
ADA Improvements Recovery House
openAlcohol & Drug Recovery Centers, Inc.
ADA Improvements Recovery House
ADA Information Services for NYS Arts
openNew York Foundation for the Arts
ADA Information Services for NYS Arts
ADA Ramps
openDorchester County
ADA Ramps
ADA Sidewalks
openTown of Thurmont
ADA Sidewalks
ADA Sidewalks
openFrederick County
ADA Sidewalks
ADA Sidewalks #2
openTown of Thurmont
ADA Sidewalks #2
ADA Sidewalks #2
openFrederick County, Maryland
ADA Sidewalks #2