Grants

16,469 grants found

24 grants worth up to $11.3M match your search

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New England Foundation for the Arts — Project Grant

New England Foundation for the Arts

Project and operating grants for arts organizations and individual artists from New England Foundation for the Arts. Supports visual, performing, literary, and media arts.

$2K – $50K

2026-12-31

artsculturecommunity arts

Free to search & build · $99 one-time to unlock the application pack · No subscription

New England Foundation for the Arts Regional Touring & Presenting Grant

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New England Foundation for the Arts

Regional arts grants supporting touring performances, exhibitions, and cultural exchange. New England Foundation for the Arts serves multiple states with NEA-funded programs for arts organizations.

$2K – $25K

2026-06-30

Arts & CultureCommunity DevelopmentEducation

Free to search & build · $99 one-time to unlock the application pack · No subscription

New FADS diet for endocrine resistant breast cancer

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NCI - National Cancer Institute

Project Summary Of the >280,000 women diagnosed with breast cancer (BrCa) in 2024, the majority will have estrogen receptor (ER) positive disease and will be treated with endocrine therapies (ET) for up to 10 years. Unfortunately, endocrine therapy resistance (ETR) develops over time in up to 30% of these women which is incurable and eventually leads to mortality despite additional targeted drugs and chemotherapy. Thus, there is an unmet need to discover modifiable factors that both prevent the development of ETR and/or impede disease progression. Environmental factors play a significant role in the development and progression of ETR. Among these, dietary n-3 polyunsaturated fatty acids (PUFAs) have a long yet controversial history of impacting breast cancer etiology. In particular, there is some discrepancy about the putative effects of “plant-based” n-3 PUFAs (alpha linolenic acid, ALA) and “marine based” n-3 PUFAs (eicosapentanoic acid, EPA; and docosahexanoic, DHA). ALA is converted to EPA/DHA in cells through a series of elongation and desaturation events catalyzed by fatty acid desaturases (FADS). Overabundance of PUFAs leads to their oxidation in the cell membrane and is a precursor for cellular damage and cell death. While preclinical and clinical studies demonstrate both types of n-3 PUFAs are associated with improved BrCa outcomes, the evidence is stronger with the marine-based n-3 PUFAs. We have generated a series of breast cancer cell lines resistant to common forms of ET. Studies in these cells have revealed a persistent ETR metabolic phenotype that includes: 1)  expression of a FADS2 isoform with high enzymatic activity; 2)  intracellular n-3 polyunsaturated fatty acids; 3)  cytoplasmic neutral lipid droplets (LDs); and 4)  lipid peroxidation /  antioxidant capacity. Our working hypothesis is that ETR BrCa cells leverage endogenous FADS2-dependent conversion of ALA to EPA and DHA (endogenous production) to support the macromolecular and energetic needs of growth and progression, while protecting the cells against the anti-tumor effects of EPA and DHA via preferential sequestering into LDs. In contrast, exogenous EPA and DHA exposure has anti-tumor effects via suppression of extracellular growth factor receptors, the suppression of BrCa FADS2 expression, and increasing fatty acid oxidation, production of reactive oxygen species (ROS), and lipid peroxidation. This proposal merges expertise in diet and nutrition, breast cancer endocrine resistance, and medical oncology to: 1) assess the impact of ALA and EPA+DHA on the growth and progression of ETR BrCa cells and tumors; and 2) determine the role of FADS2 in both the development and maintenance of the ETR phenotype. These studies will advance our understanding of how dietary plant-based and marine-based PUFAs differentially affect the development and maintenance of ETR breast cancer. They have the potential to inform specific nutritional and pharmacological interventions for improving disease outcomes in the large population of women at risk for or living with ETR BrCa.

Up to $625K

2031-04-30

health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Frontiers in Research Fund (NFRF)

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Government of Canada

NFRF supports world-leading interdisciplinary, international, high-risk/high-reward, and rapid-response research through Exploration, Transformation, and International streams.

$50K – $2M

Rolling

researchinterdisciplinaryhigh-risk

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Frontiers in the Streamlined Synthesis of N-Unprotected Chiral Heterocycles and Amines via Organo- and Transition Metal Catalysis

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NIGMS - National Institute of General Medical Sciences

Project Summary Amines and their derivatives are indispensable to pharmaceuticals, agrochemicals, materials science, and natural products. On average, the top 200 best-selling small molecule drugs contain 2.8 nitrogen atoms, with 80% featuring at least one N-heterocyclic fragment, and 45% including chiral amine moieties. This underscores the urgent need for new synthetic methods that enable the rapid and efficient incorporation of nitrogen into simple and complex molecules alike. Current limitations in C–N bond-forming strategies restrict the ability to explore new nitrogen-rich chemical spaces, which are crucial for developing next-generation drugs and biologically active compounds. Addressing these challenges requires groundbreaking approaches to nitrogen transfer that are mechanistically novel, operationally simple, and broadly applicable across diverse substrates. This proposal outlines a bold and innovative five-year research program aimed at transforming the synthesis of nitrogen-containing compounds by developing pioneering amination strategies. Our efforts will focus on mechanistically distinct processes that address unmet needs in synthetic organic and medicinal chemistry. Specifically, we propose to: (1) Develop Catalyst-Free Olefin Difunctionalization Methods: Harnessing the unique reactivity of N-acyl-N-halo-O-sulfonyl hydroxylamines, we will achieve the direct halo-hydroxylamination of feedstock olefins, enabling the one-pot synthesis of structurally complex multifunctional hydroxylamine derivatives; (2) Pioneer Photochemical and Chiral Acid-Catalyzed Aziridination: Expand the scope of NH- and N-alkyl aziridination of isolated and conjugated olefins by leveraging photochemically generated nitrenoids and chiral acid catalysis, introducing new avenues for stereoselective and regioselective nitrogen transfer; (3) Explore Non-Catalytic and Catalytic Complexity-Building Transformations: Utilize structurally diverse cyclic and acyclic O-activated hydroxylamines and oximes as electrophilic aminating agents to achieve complexity- building transformations under mild, catalyst-free, and metal-catalyzed conditions; (4) Establish Scaffold- and Functional Group-Hopping Reactions: Design external-oxidant-free nitrogen insertions into heteroarenes, enamines, and enol ethers, enabling the creation of new chemical scaffolds with broad utility in drug discovery. Each proposed method represents a significant departure from traditional approaches, offering innovative solutions to longstanding challenges in nitrogen-transfer chemistry. By uncovering the mechanistic foundations of these regio-, stereo-, and chemoselective processes, we will define new paradigms in C–N bond formation. The operational simplicity and scalability of these transformations will accelerate their adoption by synthetic and medicinal chemistry communities, ensuring lasting impact. This research will advance both the fundamental understanding and practical application of amination chemistry, bridging the gap between academic discovery and industrial innovation. These efforts will provide transformative tools to explore uncharted nitrogenous chemical spaces, catalyzing progress in organic synthesis, chemical biology, and drug development.

Up to $410K

2031-01-31

health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire CDFA Community Development Block Grant

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New Hampshire Community Development Finance Authority

New Hampshire's CDBG program provides grants to municipalities for housing, public facilities, economic development, and infrastructure projects that benefit low- and moderate-income residents in non-entitlement communities.

$50K – $500K

Rolling

Community DevelopmentHousinginfrastructure

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire CDFA Tax Credit Program

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New Hampshire Community Development Finance Authority

The CDFA Tax Credit Program provides state tax credits to businesses that invest in community development projects operated by nonprofits, supporting affordable housing, economic development, and community revitalization across New Hampshire.

$10K – $250K

Rolling

Community DevelopmentBusiness DevelopmentHousing

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire Charitable Foundation — Regional Programs Community Grants

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New Hampshire Charitable Foundation — Regional Programs

New Hampshire Charitable Foundation — Regional Programs ($1.0B in assets) supports nonprofits in NH through grants focused on education, community development, health, arts, environment. Awards range from $2,000 to $100,000.

$2K – $100K

Rolling

Educationcommunity developmentHealth+2

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire Charitable Foundation Community Grants

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New Hampshire Charitable Foundation

New Hampshire Charitable Foundation ($900M in assets) supports nonprofits in NH through grants focused on education, health, community development, arts, environment. Awards range from $2,000 to $150,000.

$2K – $150K

Rolling

EducationHealthcommunity development+2

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire DES Clean Water State Revolving Fund

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New Hampshire Department of Environmental Services

The Clean Water SRF provides low-interest loans and principal forgiveness grants to New Hampshire municipalities for wastewater treatment improvements, stormwater management, and nonpoint source pollution control projects.

$100K – $5M

Rolling

environmentinfrastructureHealth

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire DES Watershed Assistance Grants

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New Hampshire Department of Environmental Services

DES Watershed Assistance Grants support local organizations and municipalities in developing and implementing watershed management plans, water quality monitoring, and restoration projects to protect New Hampshire's lakes, rivers, and streams.

$5K – $50K

Rolling

environmentCommunity Developmentresearch

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire Division of Economic Development Business Finance Programs

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New Hampshire Department of Business and Economic Affairs

The Division of Economic Development offers grants and financing assistance to New Hampshire businesses for expansion, job creation, and workforce training, with emphasis on manufacturing, technology, and export-oriented industries.

$10K – $200K

Rolling

Business Developmentworkforcetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire Housing Finance Authority Affordable Housing Fund

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New Hampshire Housing Finance Authority

NHHFA's Affordable Housing Fund provides grants and loans to developers and nonprofits for creating and preserving affordable housing units across New Hampshire, addressing the state's critical housing shortage.

$50K – $500K

Rolling

HousingCommunity DevelopmentEquity & Access

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire Humanities Council Grants

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New Hampshire Humanities Council

Grants for humanities programming including lectures, exhibitions, oral history, documentary, and public humanities projects in New Hampshire. Funded by NEH.

$500 – $8K

Rolling

EducationArts & CultureCommunity Development

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire State Council on the Arts Operating Grants

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New Hampshire State Council on the Arts

Operating grants provide general support to established New Hampshire arts organizations for sustaining core arts programming, building audiences, and strengthening organizational capacity across the state.

$1K – $15K

Rolling

Arts & CultureCommunity Development

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Hampshire State Council on the Arts Project Grants

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New Hampshire State Council on the Arts

Project grants support specific arts activities including festivals, exhibitions, performances, arts education programs, and community arts projects that expand public engagement with the arts in New Hampshire communities.

$500 – $8K

Rolling

Arts & CultureEducationEquity & Access

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Holly Youth and Family P-Patch Fence

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New Holly Youth & Family P-Patch

A P-Patch fence around the 390' exterior perimeter is needed for the safety and security of community participants. Problems we want to address include: physical threats to gardeners (many of whom are older and immigrants), theft of garden tools, damage to the storage shed, and transients staying overnight in the storage shed. A problem unique to our large immigrant gardening population is that stolen produce significantly compounds common food insecurity. This is because these gardeners grow produce with which they are familiar and use a lot, but which is hard to find in local grocery stores.

Up to $23K

Rolling

Agriculture

Free to search & build · $99 one-time to unlock the application pack · No subscription

New ionization source technology for single-cell multi-omics

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NIGMS - National Institute of General Medical Sciences

This project will develop, optimize and evaluate the analytical performance of a new tool, termed Thermal Ink Jet Spray (TIJ Spray). TIJ Spray will enable the direct injection of low input samples, including individual cells, into mass spectrometers for multi-omics analysis to enable discovery of cell phenotypic heterogeneity of drug response. TIJ Spray in conjunction with ion mobility spectrometry and integrated with high-resolution tandem mass spectrometers (IMMS) promises of providing the necessary throughput, sensitivity and specificity for detecting and characterizing cell type heterogeneity, subpopulation heterogeneity and drug response based on molecular ion profiles. Comprehensive characterization of the proteome and metabolome of individual cells allows inferring the functional state of individual cells and reveals functional phenotype heterogeneity. Knowledge of existence of functionally heterogeneous phenotypes is of relevance for the biology of tumors and tumor microenvironments because of the presence of highly heterogeneous cell populations and possible presence of cells of the same type but displaying different functional and metabolic phenotypes. Distinct phenotypes are masked in bulk cell populations, which hinders the discovery and validation of phenotype-specific biomarkers as well as confounds drug discovery. In this high risk/high reward project, we will develop this new technology and demonstrate its analytical performance for multi-omic analysis of single cells by accomplishing the following specific aims: Aim 1: Develop and optimize TIJ spray and its technical integration with IMMS. We will develop TIJ spray and demonstrate its the analytical capabilities in conjunction with IMMS for detection of different classes of analytes including those found in individual cells. Aim 2: Demonstrate TIJ Spray IMMS for multi-omics of single cells for cellular phenotyping and detection of phenotype-specific drug response. We will demonstrate and evaluate performance of TIJ Spray IMMS for obtaining multi-omics data in a pathobiologically relevant context and evaluate its analytical performance for detecting multi-omics changes, and differential drug uptake and response. When successful, we aim for achieving throughput of several hundreds of cells per day resulting in high quality multi-omic profiles for single-cell functional phenotyping. When we can show “fitness for purpose”, TIJ Spray IMMS has the potential to democratize single-cell mass spectrometry making it available for a wider range of laboratories and the biomedical community.

Up to $408K

2028-02-29

health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey Area Agency on Aging — Community Grants

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New Jersey Area Agency on Aging

Grants from New Jersey's Area Agencies on Aging for programs serving older adults including nutrition, transportation, caregiver support, and health promotion.

$10K – $75K

2026-09-01

senior servicesnutritiontransportation+1

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey Arts Council General Operating Support

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New Jersey Council on the Arts

General operating support grants for arts organizations in New Jersey. Funded by the National Endowment for the Arts and state appropriations.

$3K – $150K

2026-06-30

Arts & CultureCommunity Development

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey Arts Council Project Grants

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New Jersey Council on the Arts

Project-based grants for arts programming, performances, exhibitions, and community engagement in New Jersey.

$3K – $150K

2026-06-30

Arts & CultureCommunity DevelopmentEducation

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey Community Development Corporation Grants

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New Jersey Community Development Corporation

NJCDC provides grants and technical assistance to community development organizations in New Jersey for affordable housing, economic opportunity, community organizing, and neighborhood revitalization in underserved communities.

$10K – $200K

Rolling

Community DevelopmentHousingeconomic_development+1

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey DD Council — Community Grants

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New Jersey Council on Developmental Disabilities

Grants from the New Jersey Developmental Disabilities Council for community inclusion, self-advocacy, and systems change projects.

$10K – $75K

2026-09-01

developmental disabilitiescommunity inclusionself-advocacy+1

Free to search & build · $99 one-time to unlock the application pack · No subscription

New Jersey Department of Agriculture Rural Development Grants

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New Jersey Department of Agriculture

The NJDA provides grants to farmers, agricultural organizations, and rural communities for farmland preservation, agricultural development, food access programs, and rural economic development across New Jersey.

$10K – $300K

Rolling

AgricultureCommunity DevelopmentEnvironmental

Free to search & build · $99 one-time to unlock the application pack · No subscription