The purpose of this investment is to further the purposes of the California Global Warming Solutions Act (Assembly Bill 32), reduce methane emissions from landfills and further GHG reductions in upstream resource management and manufacturing processes; benefit disadvantaged communities by upgrading existing facilities and, where warranted, establishing new facilities that reduce GHG emissions; result in air and water quality improvements; and create jobs.

Up to $5.5M

Rolling

energy; environment & water

Free to search & build · $99 one-time to unlock the application pack · No subscription

Greentown Labs Climate Tech Grants

open

Greentown Labs

North America's largest climate tech startup incubator. Provides lab space, prototyping facilities, mentorship, and grant funding for climate solutions.

$25K – $250K

Rolling

climate techclean energyhardware+1

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

open

National Institutes of Health

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

2026-10-30

general

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)

open

National Institutes of Health

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Data Coordination and Outreach Center. The Data Coordination and Outreach Center will act as the central point of coordination for the GREGoRi Research Program, and will be responsible for ensuring that the protocols, data, metadata, computational tools and other resources developed as part of GREGoRi are made available to the broader research community.

Up to $1.3M

2026-10-30

Healthhealthcare

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

open

National Institutes of Health

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. This Notice of Funding Opportunity is intended to stimulate the development and testing of highly innovative experimental or computational approaches for rare disease diagnosis, that have the potential to make transformative improvements to the current state of the art.

$3 – $500K

2026-10-30

Healthhealthcare

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

open

National Institutes of Health

GREGoRi Innovation Projects (U01 Clinical Trial Optional)

2026-10-30

innovation

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

open

National Institutes of Health

The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center will be a multidimensional dataset that can be used for the development and benchmarking of novel tools and strategies that facilitate rare disease diagnosis.

Up to $2.3M

2026-10-30

Healthhealthcare

Free to search & build · $99 one-time to unlock the application pack · No subscription

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

open

National Institutes of Health

GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

2026-10-30

technology

Free to search & build · $99 one-time to unlock the application pack · No subscription

Grid Deployment Office (GDO) — Grid Resilience Grants

open

U.S. Department of Energy

Funds grid hardening, modernization, and resilience improvements to prevent outages and facilitate integration of clean energy into the electric grid.

$2M – $100M

2026-08-01

grid resiliencegrid modernizationenergy infrastructure

Free to search & build · $99 one-time to unlock the application pack · No subscription

GRK5 regulation of GPCR signaling in platelets.

open

NHLBI - National Heart Lung and Blood Institute

Project Summary Cardiovascular and cerebrovascular diseases have historically been among the most common causes of death in the United States. Venous thromboembolism (VTE), heart attack, and stroke are all diseases in which platelets play a role through inappropriate platelet activation and subsequent platelet plug formation. Most platelet activators stimulate platelets via G protein- coupled receptors (GPCRs). Our goals are to elucidate the mechanisms responsible for the feedback regulation of GPCRs during platelet activation and to investigate how the thrombin receptor can be negatively regulated by GPCR kinase 5 (GRK5). Changes in GRK expression have been linked to many cardiovascular diseases. The roles of GRK subtypes are highly cell-, receptor-, and disease-specific. We first reported that GRK5 normally limits platelet activation downstream of GPCRs and that removing the GRK5-dependent limits on GPCR signaling produces a prothrombotic state. More recently, we reported genome-wide association studies (GWAS) of pathway-specific functional responses to thrombin receptor-agonist peptides in subsets of 1,562 individuals. We identified a genetic variant in GRK5 and the sensitivity of platelets to activate through the thrombin receptor PAR1. The minor allele (G) is associated with decreased GRK5 expression in platelets, greater sensitivity of platelets to activate through PAR1, and increased risks of cardiovascular diseases. These studies in humans, combined with findings from platelet studies in GRK5-/- mice, and the preliminary data provided herein provide strong evidence that GRK5 is a critical negative regulator of platelet activation via PAR1 and P2Y receptors. We hypothesize that GRK5 is an important regulator of GPCR-mediated platelet function and can be manipulated to manage platelet dysfunction in disease. The hypothesis will be tested with three specific aims. In Aim 1, we will delineate the mechanisms by which GRK5 regulates platelet activation via a subset of GPCRs. In Aim 2, we will determine how the activity of GRK5 is regulated in platelets. In Aim 3, we will investigate the role of GRK5 in pathological thrombus formation, including VTE and stroke. The proposed studies will 1) provide the first insight into how GRK5 regulates GPCR signaling and how GRK5 itself can be regulated in platelets, and 2) lay the groundwork for optimizing antiplatelet therapy for the nearly 2% of the US population who are homozygous for the high-risk GRK5 G-allele.

Up to $763K

2030-01-31

health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Ground and naval platforms and systems

open

European Commission - EDF

Ground and naval platforms and systems. Call: 2nd call for proposals for common procurement actions under the Programme. Programme: EDF. Open call from the EU Funding & Tenders Portal.

$50K

2027-02-16

research

Free to search & build · $99 one-time to unlock the application pack · No subscription

GROUND BASED STUDIES IN RADIOBIOLOGY 2013

open

NASA Johnson Space Center

The National Aeronautics and Space Administration (NASA) plans to release a NASA Research Announcement (NRA), for Ground-based Studies for the Space Radiation Program Element (SRPE) in the area of space radiobiology of cancer and neuronal risks utilizing beams of high energy ions simulating space radiation at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL) in Upton, New York. NASA Research Announcement # NNJ13ZSA001N, entitled "Ground-Based Studies in Space Radiobiology", will be available electronically on or about February 11, 2013, by opening the NASA Research Opportunities homepage at http://nspires.nasaprs.com/ and then linking through the menu listings "Solicitations" to "Open Solicitations". Step-1 proposals are due on March 13, 2013, and invited Step-2 proposals are due on May 22, 2013. Proposals are required to be submitted electronically and must be submitted by an authorized official of the proposing organization. Participation is open to all categories of organizations, including educational institutions, industry, nonprofit organizations, NASA centers, and other Government agencies. Electronic proposals may be submitted via the NASA centers, and other Government agencies. Electronic proposals must be submitted via the NASA Proposal data system NSPIRES. Every organization that intends to submit a proposal in response to this NRA must be registered with NSPIRES, and such registration must identify the authorized organizational representative(s) who will submit the electronic proposal. Each electronic proposal system places requirements on the registration of principal investigators and other participants (e.g. co-investigators). Potential proposers and proposing organizations are urged to access the system(s) well in advance of the proposal due date(s) of interest to familiarize themselves with its structure and enter the requested information. Questions concerning responding to this NRA may be addressed to the contacts referenced in the full solicitation document. This is a broad agency announcement as specified in FAR 6.102 (d)(2). Notwithstanding the posting of this opportunity at FedBizOpps.gov, or nspires.nasaprs.com, NASA reserves the right to determine the appropriate award instrument for each proposal selected pursuant to this announcement.

Up to $450K

rolling

sciencetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription

GROUND-BASED STUDIES IN SPACE RADIOBIOLOGY

open

NASA Johnson Space Center

The National Aeronautics and Space Administration (NASA) plans to release a NASA Research Announcement (NRA), for Ground-based Studies for the Space Radiation Program Element (SRPE) in the area of space radiobiology of cancer and neuronal risks utilizing beams of high energy ions simulating space radiation at the NASA Space Radiation Laboratory (NSRL) at Brookhaven National Laboratory (BNL) in Upton, New York. NASA Research Announcement # NNJ12ZSA001N, entitled "Ground-Based Studies in Space Radiobiology", will be available electronically on or about January 26, 2012, by opening the NASA Research Opportunities homepage at http://nspires.nasaprs.com/ and then linking through the menu listings "Solicitations" to "Open Solicitations". Step-1 proposals are due on February 29, 2012, and invited Step-2 proposals are due on May 9, 2012. Proposals are required to be submitted electronically and must be submitted by an authorized official of the proposing organization. Participation is open to all categories of organizations, including educational institutions, industry, nonprofit organizations, NASA centers, and other Government agencies. Electronic proposals may be submitted via the NASA centers, and other Government agencies. Electronic proposals must be submitted via the NASA Proposal data system NSPIRES. Every organization that intends to submit a proposal in response to this NRA must be registered with NSPIRES, and such registration must identify the authorized organizational representative(s) who will submit the electronic proposal. Each electronic proposal system places requirements on the registration of principal investigators and other participants (e.g. co-investigators). Potential proposers and proposing organizations are urged to access the system(s) well in advance of the proposal due date(s) of interest to familiarize themselves with its structure and enter the requested information. Questions concerning responding to this NRA may be addressed to the contacts referenced in the full solicitation document. This is a broad agency announcement as specified in FAR 6.102 (d)(2). Notwithstanding the posting of this opportunity at FedBizOpps.gov, or nspires.nasaprs.com, NASA reserves the right to determine the appropriate award instrument for each proposal selected pursuant to this announcement.

Up to $450K

rolling

sciencetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription