Grants

NYC Department of Cultural Affairs

Asian American Arts Alliance

NYC Department of Cultural Affairs

Asian American Film Lab, Inc.

NYC Department of Cultural Affairs

Asian American Writers' Workshop

Asian Entrepreneurship Foundation

Asian Entrepreneurship Foundation is an active grantmaking foundation based in Boston, MA. Focus: general. Contact the foundation directly for current funding opportunities.

Chinatown-International District Exhibit Committee

The Chinatown-International District Exhibit Committee's COVID-19 Exhibit will educate the public about the effects of COVID-19 on Asian Pacific Islander Americans in the Chinatown-International District through a free digital exhibit of art, personal stories, and artifacts. This project is a partnership with the Wing Luke Museum located at 719 S King Street. This project will be completed by December 31,2021.

HEALTH AND HUMAN SERVICES, DEPARTMENT OF.NATIONAL INSTITUTES OF HEALTH.NATIONAL INSTITUTES OF HEALTH - CC

ASIT.TO 1 year software support from ArgonSoft (Notice of Intent to sole source)

FIC - John E. Fogarty International Center for Advanced Study in the Health Sciences

Abstract/Project Summary Despite recent improvements in adolescent sexual and reproductive health (ASRH) outcomes in Kenya, rates of unsafe sex, unplanned pregnancy, abortion, and sexually transmitted infections remain high. While schoolbased comprehensive sexuality education (CSE) improves ASRH outcomes, the Kenyan government tends to support less thorough programs, and teachers face challenges (e.g., lack of time, training, resources) that hinder sexuality education instruction. Adolescents who do not receive adequate CSE instruction lack the information needed to make informed sexual and reproductive health decisions. Thus, there is pressing need to identify innovative interventions to provide CSE outside the formal educational system. Mobile health (mHealth) technology may provide a cost-effective solution. Amref Health Africa–Kenya developed/tested an artificially intelligent mHealth WhatsApp chat bot, AskDoki, to deliver CSE. Preliminary data suggest improved effectiveness and outreach might be obtained, especially among adolescents who lack phones, by pairing AskDoki with “tech savvy” youth peer leaders or “Digital Champions” (DCs). In collaboration with Amref, we will implement AskDoki among adolescents via DC outreach and facilitation to address our specific aims: R21 Aim 1a) Examine the effectiveness of AskDoki-delivered CSE in improving key determinants of ASRH behaviors/ outcomes via a quasi-experimental, two-group (intervention vs. control clusters), non-equivalent, pre/post survey design with adolescents aged 15-19. Primary outcomes for comparison will be increases in perceived control (e.g., condom-use self-efficacy), positive attitudes (e.g., condom use), subjective norms (e.g., peer support of condom use), knowledge (e.g., pregnancy, STIs), and intentions (e.g., to use condoms). R21 Aim 1b) Conduct a process evaluation of the DC strategy to promote/facilitate AskDoki access. We will collect data from multiple sources to assess adolescent reach, acceptability, and uptake of the DC strategy. We will also conduct two sets of focus groups: with Aim 1a adolescents to explore DC perceptions and experiences and to identify improvement areas; and with DCs to explore barriers and facilitators. R21 Aim 2) Conduct cost effectiveness analyses for the AskDoki and DC strategy. We will track start-up, operational, and incremental per-use costs and compute cost per adolescent served and cost per adolescent who makes progress on one and on at least three outcome measures. R33 Aim 3) Evaluate a scaled deployment of AskDoki using RE-AIM framework. We will examine Reach (adolescents accessing AskDoki), Effectiveness (Aim 1 outcomes, condom use, pregnancy reduction, willingness to test/treat STIs, use of SRH services); Adoption (representativeness of AskDoki users, characteristics of curriculum completers); Implementation (interviews with adolescents to explore barriers, facilitators, scaled deployment cost); and Maintenance (sustained effectiveness of primary/secondary outcomes). Findings may inform scalable interventions that provide U.S. adolescents with health information that ultimately helps to improve youth outcomes.

NIMHD - National Institute on Minority Health and Health Disparities

Modified Project Summary/Abstract Section The mental health experiences of Black autistic youth (Black-AY) have been severely understudied and are often unaddressed, particularly concerning their experiences with depression and depressive symptoms. Black youth, in general, are at an increased risk of experiencing depression while navigating challenges related to being autistic. Recent studies indicate that Black-AY are significantly more likely to report depressive symptoms and frequently encounter difficulties with essential social communication skills necessary for effectively expressing their mental health needs. These findings have led us to develop an informed mobile health (mHealth) tool to support Black-AY in communicating about depression and effectively seeking mental health support. The Asking for Help program (A4H) utilizes simulated conversations and depression literacy content to enhance help-seeking behaviors through improved social communication and depression literacy for Black-AY. The proposed study employs a user-centered mixed-methods design, incorporating a convergent parallel mixed-methods methodology with a user-centered approach to 1) evaluate the acceptability, usability, and feasibility of Asking for Help; 2) modify and refine A4H to optimize its effectiveness for Black-AY; and 3) apply a quasi-experimental one-group pre-test post-test design to assess A4H's efficacy in enhancing participants’ understanding and knowledge about depression, mental health communication, self-efficacy, anxiety, and overall mental health help-seeking attitudes. The findings will expand scholarly knowledge of the depression experiences and mental health help-seeking behaviors of Black autistic youth by developing a program intended to significantly impact their mental health by offering relevant resources and personalized care that will help these youth thrive and achieve mental wellness.

Aslan Housing Foundation

Aslan Housing Foundation is an active grantmaking foundation based in Redwood City, CA. Focus: general. Contact the foundation directly for current funding opportunities.

Dance Complex

ASP Neighborhood Projects

Regional Council Capital Fund - RC6

ASP Partners Phase II Capital

Regional Council Capital Fund - RC 2

ASP Partners Phase II Capital

NSF

Classical dynamics studies how systems change in time. Ergodic theory, a subfield of dynamics, focuses on the statistical behavior of dynamical systems. Applications of ergodic theory are widespread: from traffic modeling to aerospace engineering and population dynamics. It is natural and of practical importance to generalize the role of time in a dynamical system to more complicated groups of symmetries. This generalized notion of dynamics leads to applications in statistical physics, number theory and geometry. However, new tools are needed when the group of symmetries is non-amenable which means that boundary phenomena are too significant to be safely ignored. One such tool is the weak local (or Benjamini-Schramm) limit. These limits formalize the asymptotic local behavior of large, possibly random, mathematical objects. This project is concerned with fundamental questions: when do these limits exist (for natural families of low-dimensional geometric objects) and given an infinite mathematical object (such as a manifold or network), can it be identified as the weak local limit of finite objects? This research project has three main objectives. 1) In recent work with M. Chapman, A. Lubotzky and T. Vidick, the primary investigator (PI) settled the Aldous-Lyons Conjecture in the negative: there exist non-sofic unimodular random graphs. These are random rooted graphs which cannot be approximated by finite graphs in the Benjamini-Schramm sense despite satisfying the Mass Transport Principle. One goal of this project is to find explicit non-sofic unimodular random graphs which are either hyperbolic, the 1-skeleton of a CAT(0) cubical complex, falsify the analog of Gottschalk’s Conjecture regarding cellular automata or which have isomorphic Bernoulli shift spaces with different entropies. These may all be useful in finding non-sofic groups, a long-sought-after goal. 2) In recent work with K. Rafi and H. Vallejos, the PI proved that Masur-Veech random translation surfaces have a weak local (Benjamini-Schramm) limit as genus tends to infinity. The main tool is an elaboration on the surgery techniques of Eskin-Masur-Zorich. The PI intends to build on this by developing multi-parameter Siegel-Veech Theory and proving weak local limits of hyperbolic surfaces decorated with measured laminations, abelian differentials, quasi-Fuchsian embeddings and so on. The PI will investigate connections between these objects and Gaussian analytic functions, SLE curves, and the Curien-Warner Markovian triangulation. 3) In celebrated work, J. Friedman proved that random d-regular graphs admit an almost maximal spectral gap with high probability as the number of vertices tends to infinity. Recent work of the PI and student A. Embry generalize this to the degree-regular block model (DRBM). A third objective of this project to extend this to generalize the Bordenave-Collins Theorem (proving strong convergence of random permutation representations of free groups) to strong convergence of a related block model version. If successful, this may show that Koopman representations of measure-preserving actions of free groups determine C*-algebras that are matricial field: they can be strongly approximated through maps to finite-dimensional algebras. It should also determine precise spectral properties of this large and varied class of sparse random graphs. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

Aspen Art Museum Foundation

Aspen Art Museum Foundation is an active grantmaking foundation based in Aspen, CO. Focus: arts. Contact the foundation directly for current funding opportunities.

Aspen Community Foundation

Aspen Community Foundation is an active grantmaking foundation based in Basalt, CO. Focus: philanthropy. Contact the foundation directly for current funding opportunities.

Aspen Education Foundation

Aspen Education Foundation is an active grantmaking foundation based in Aspen, CO. Focus: workforce development. Contact the foundation directly for current funding opportunities.

NIAID - National Institute of Allergy and Infectious Diseases

Aspergillus fumigatus causes an array of respiratory diseases ranging from acute invasive aspergillus to allergic sensitization from chronic colonization. Allergic bronchopulmonary aspergillosis (ABPA) is one of the most severe and devasting chronic diseases caused by Aspergillus fumigatus. ABPA is particularly important in people with Cystic Fibrosis (pwCF) as it is associated with worsening lung function and increased frequency of exacerbations in those individuals. ABPA is associated with fungal persistence in the lungs, ultimately leading to fungal sensitization, characterized by high total serum IgE levels, as well as a large increase in airway Th2 cytokines that drive airway eosinophilia. Currently, there is a critical knowledge gap in our understanding of the host-pathogen interactions which enable certain Aspergillus fumigatus strains to persist long-term in the lungs thus driving fungal sensitization and ABPA disease progression. In collaboration with colleagues within the Dartmouth Cystic Fibrosis Research Center (DartCF) we have developed a novel ABPA murine model, which we will use to understand both the fungal and host factors enabling fungal persistence and ABPA disease initiation and progression. This proposal fills the aforementioned knowledge gap by examining both the role host lung-resident macrophages in establishing a protective, long-term survival niche for fungal persistence and alterations in fungal resistance to antifungal killing by those same lung-resident macrophages can alter ABPA disease initiation and progression. In SA1, we will determine the fungal- intrinsic pathways enabling Aspergillus fumigatus to persist in those lung-resident alveolar macrophages. Moreover, we will utilize a library of clinical Aspergillus fumigatus isolates from pwCF to determine if there is a selection of these pathways. In SA2, we examine the host pathways within the lung-resident alveolar macrophages which are responsible for long-term persistence of those cells after Aspergillus fumigatus engagement using classic immunological techniques (e.g. conditional knock-out mice and adoptive transfers) and a novel pooled genetic screen. Finally, we seek to provide proof-of- concept data that targeting these lung-resident macrophage populations could alter the disease course of ABPA in our mouse model. Together, these data will provide novel insights into mechanisms of fungal persistence which aids in the development and progression of ABPA in mammals. Overall, this research fills a critical gap by providing the field with a better understanding of how fungal traits beyond allergen expression may regulate chronic allergic fungal diseases, like APBA, while also identifying a unique host-targeted therapeutic approach to limit Aspergillus fumigatus persistence within the lungs of a mammalian host to ameliorate chronic fungal disease.

FALCON ROAD MAINTENANCE EQUIPMENT LLC

Service Industry Machinery and Equipment and Supplies

NSF

The Alumni, Students, Professors, Internships, Research, Enrichment (ASPIRE) to Careers in Science 2 project will contribute to the national need for well-educated scientists, mathematicians, engineers, and technicians by supporting the retention and graduation of high-achieving, low-income students with demonstrated financial need at Molloy University, a Hispanic-Serving Institution. Over its six-year duration, this Track 2 grant will fund scholarships, for four years, to 22 unique full-time students pursuing bachelor’s degrees in biology or earth and environmental sciences (EES). The project offers high-impact activities and best practices to achieve stronger retention and graduation rates, increased student learning, and a greater chance of successful transition to STEM-related employment or graduate study upon graduation. Throughout the four years of undergraduate study, cohort activities include curriculum-embedded research, three-tiered mentoring, self-study online tutorial modules for STEM courses, paid summer employment or research internship opportunities, and an enrichment workshop series focused on post-graduate success. An important focus is to prepare scholars to work in basic biological laboratory research, field work, and technology to assume employment in these job sectors that anticipate future growth. Local, state, regional, and national domains will benefit from the addition of academically prepared, well-trained scientists to work in key life science and environmental science fields. The overall goal of this project is to increase STEM degree completion of high-achieving, low-income undergraduates with demonstrated financial need. Evidence-based activities intend to meet the following objectives: enroll 22 full-time biology or EES majors in three cohorts; award annual scholarships to meet their unmet need; obtain a first-to-second year retention rate of 80%; increase student success rate by 5% in specified undergraduate major STEM requirements known to be hurdles; and support scholars to pursue graduate study or accept employment in a science-related field post-graduation. Assessment efforts will focus on generating knowledge regarding effective program design for diverse student populations. Psychosocial aspects of the enhanced cohort experience and inclusion of family information sessions that address financial concerns will be examined along with STEM job opportunities in fields other than healthcare, and differences in cultural needs of students. Additionally, the findings will contribute to the knowledge base of how the design of four-year STEM programs inform academic and psychosocial effects on student persistence and success in careers in science. Project activities, services, and financial support specifically designed to aid retention will demonstrate their value in retaining students, improving grades, and encouraging students to graduate in four years. An extensive evaluation plan will involve both formative and summative approaches and results will be used internally to inform and improve STEM programming for all Molloy students. External dissemination will include authored publications and presentations at professional conferences. This project is funded by NSF's Scholarships in Science, Technology, Engineering, and Mathematics program, which seeks to increase the number of academically talented, low-income students with demonstrated financial need who earn degrees in STEM fields. It also aims to improve the education of future STEM workers, and to generate knowledge about academic success, retention, transfer, graduation, and academic/career pathways of low-income students. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

National Institutes of Health

Assay development and screening for discovery of chemical probes, drugs or immunomodulators (R01 Clinical Trial Not Allowed)

National Institutes of Health

Assay Development and Screening for Discovery of Validated Chemical Hits for Brain Disorders (R01 Clinical Trial Not Allowed)

National Institutes of Health

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH2/UH3 Clinical Trial Not Allowed)

National Institutes of Health

Assay Validation of High Quality Markers for Clinical Studies in Cancer (UH3 Clinical Trials Not Allowed)

NSF

The numerous molecular interactions that support life must be highly regulated in the cell to achieve selectivity and precision. A newly identified method with which cells achieve this is via the sequential assembly of filamentous signaling platforms which are composed of a specific class of proteins. These large, supramolecular structures adopt distinct architectures, and shape complementarity plays a key role in recognizing their specific partners. Their assembly provokes a “signal” which triggers a cellular response. The filamentous signaling hubs can condense into large organelle-like entities, which can be vital for preventing any crosstalk with unrelated signaling pathways. This project aims to investigate how filamentous signaling platforms assemble and operate at the molecular level. This information is fundamental to understanding the coordination of the complex network of cellular processes. The PI directs the Biophysics Research for Baltimore Teens (BRBT) program, an outreach program in which high school students from Baltimore and the surrounding areas can be part of current research efforts. Specifically, this project will investigate how filamentous signaling platforms execute a cell-death pathway. The research strategy includes computational methods such as Rosetta, Electron Microscopy, single-molecule force measurements, and quantitative assays in both cell-free and cell-based systems. The first goal is to determine how architectural complementary dictates the interacting partners within a specific group of signaling filaments. The second goal is to investigate the mechanical forces involved in assembling such filamentous structures on DNA. The third goal is to elucidate how different regulators target and inhibit specific signaling components in these pathways. The outcome here will delineate structural, biochemical, physical mechanisms by which filamentous assemblies preserve the signaling specificity at different stages of the cell-death pathway. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.