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National Institutes of Health

Purpose. This Funding Opportunity Announcement (FOA) issued by the National Institute of Nursing Research (NINR), National Institute of Child Health and Human Development (NICHD), National Heart, Lung, and Blood Institute (NHLBI), National Institute on Alcohol, Alcoholism, and Alcohol Abuse (NIAAA), National Cancer Institute (NCI), and National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), solicits Exploratory/Developmental Grant (R21) applications from institutions/organizations that propose to conduct research to reduce health disparities among minority and underserved children. Specifically, this initiative focuses on ethnic and racial minority children and underserved populations of children such as: children from low literacy, rural and low-income populations, geographically isolated children, hearing and visually impaired children, physically or mentally disabled children, children of migrant workers, children from immigrant and refugee families, and language minority children. Specific targeted areas of research include biobehavioral studies that incorporate multiple factors that influence child health disparities such as biological (e.g., genetics, cellular, organ systems), lifestyle factors, environmental (physical and family environments), social (e.g., peer influences), economic, institutional, and cultural and family influences; studies that target the specific health promotion needs of children with a known illness and/or disability; and studies that test and evaluate the cost effectiveness of health promotion interventions conducted in nontraditional settings.

NCI - National Cancer Institute

PROJECT SUMMARY County boundaries are the dominant unit for cancer surveillance in the United States, yet they are poorly suited for capturing meaningful geographic variation in population cancer burden. In states like Texas, home to both large, demographically complex urban centers and sparsely populated rural areas, county-level reporting often obscures critical geographic differences. A large proportion of rural counties frequently face data suppression due to small populations and incident cases of cancers, while large urban counties mask high-burden neighborhoods behind aggregated statistics. These limitations hinder public health efforts to identify, monitor, and respond to geographic differences in cancer outcomes. This is especially problematic for cancer prevention and control efforts of breast, colorectal, and lung cancers, which account for nearly 50% of all cancer incidence and 45% of deaths annually in Texas. Previous studies have explored alternatives to county- based cancer reporting by using spatial clustering methods that aggregate census tracts or ZIP codes. However, these approaches typically rely on static, user-defined rules and thresholds, limiting their ability to balance critical trade-offs—such as minimizing data suppression, maximizing geographic granularity, and ensuring demographic homogeneity needed for responsive public health action. To address this critical gap, we propose a novel Geographic Artificial Intelligence (GeoAI) approach, specifically the application of Neural Cellular Automata and Graph Neural Networks, to create sub-county geographic boundaries to improve cancer surveillance using individual-level cancer incidence data from the Texas Cancer Registry (2018–2022). The first aim of our project will develop and test GeoAI-based sub-county geographic zones for breast, colorectal, and lung cancer surveillance that minimize data suppression, improve demographic homogeneity, and enhance spatial coherence across Texas. In our second aim, we will leverage the newly created GeoAI- defined zones to examine geographic variation in late-stage incidence and cancer-specific mortality, identifying high-burden areas obscured by traditional county boundary reporting. This project represents the first use of Neural Cellular Automata and Graph Neural Networks to construct flexible, data-driven geographic units optimized for cancer surveillance. These methods will allow us to generate zones that are population-stable, demographically meaningful, and tailored to local context. At the end of the study, we will have created a generalizable framework that reduces data suppression, uncovers hidden geographic cancer variation, and improves the spatial precision of cancer surveillance, offering new tools for targeting prevention and control efforts at the community level.

NCI - National Cancer Institute

PROJECT SUMMARY/ABSTRACT Rural cancer survivors face a 10% higher risk of cancer-related mortality than those living in urban areas. Despite evidence that increased physical activity after a cancer diagnosis is associated with a 20-40% decrease in cancer-related mortality, rural cancer survivors are 31% more likely to report being physically inactive. This is an indication that lack of physical activity is a key factor driving higher mortality rates in rural communities. Previous work has identified that few interventions have been implemented addressing the specific needs and challenges for delivering physical activity programming in rural communities. The development of a contextually supported and methodologically rigorous intervention designed to address low physical activity among rural cancer survivors is needed. This proposed study aims to develop and evaluate RUCAS (Rural Cancer Survivorship), a personalized, place-based digital health intervention to promote adherence to physical activity guidelines among cancer survivors living in rural areas. The objective of the K99 phase is to develop the RUCAS intervention using an explanatory sequential mixed methods evaluation of rural cancer survivors. Aim 1 (K99) is to characterize and compare the demographic and geographic factors of rural cancer survivors who are interested in using a digital health intervention and to identify desired intervention components using a cross-sectional survey. Aim 2 (K99) is to assess the intervention components using semi-structured interviews with rural cancer survivors who indicated interest in a digital health intervention. The objective of the R00 phase is to optimize and test the RUCAS intervention in preparation for a larger randomized controlled trial. Aim 3 (R00) is to refine the RUCAS intervention using survey and interview evaluation data from a usability study. Aim 4 (R00) is to assess the feasibility, acceptability, and preliminary patterns of change in physical activity of the RUCAS intervention during a single-arm pilot study. Dr. Werts- Pelter’s long-term career and research goal is to establish herself as an independently funded cancer prevention and control researcher investigating the implementation of lifestyle behavior change interventions which address poor health outcomes among rural cancer survivors. To achieve this goal, Dr. Werts-Pelter proposes specialized training in physical activity intervention, the development and use of digital technology as a tool for health behavior intervention, and rural health. The proposed training will be completed under the mentorship of a robust team of investigators chosen based on their demonstrated success in academic research environments and their expertise in these desired areas of career growth. The proposed research and training plan will enable Dr. Werts-Pelter to transition to independence by providing protected time to develop new research skills, to collect preliminary pilot data, submit manuscripts, and, ultimately, to submit a competitive R01 application to establish herself as an independently funded investigator.

Rural Action

Community-led economic and environmental development in Appalachian Ohio

69A345 Office of the Under Secretary for Policy

New versions of the Notice of Funding Opportunity documents have been published on March 13, 2025 and are available under the "Related Documents" tab. Note that the application portal opening date has been rescheduled to March 18, 2025 at 2:00 p.m. ET. The purpose of this notice is to solicit applications for Rural and Tribal Assistance (RTA) Pilot Program grants. A total of $27 million is available to award for planning and design phase activities for developing transportation projects in rural or tribal communities. Grants will support hiring staff or expert firms to provide technical, legal, or financial assistance to advance transportation projects that would be reasonably expected to be eligible for select Department of Transportation discretionary grant or credit programs. There is no local match required to participate in this program. Grants are awarded on a first-come, first-served basis to eligible applicants with an eligible project who meet the merit criteria described in the Notice of Funding Opportunity. The application form to apply for Program funding will be available beginning at 2:00 p.m. ET on March 18, 2025 on the Program's webpage: https://www.transportation.gov/buildamerica/RuralandTribalGrants. This is the only place where applications can be submitted and will be accepted. Do not submit applications through grants.gov. A pdf (one each for Single Project and Multi-Community grants) of the application questions is included in the NOFO package available under the "Related Documents" tab of this grants.gov page and is also available on the Program's webpage link above. Two types of grants will be awarded: Single Project grants and Multi-Community grants, which will fund projects in, at minimum, three separate communities submitted under a single application. Single Project grants: $10 million available to award Min. award amount: $200,000 Max. award amount: $750,000 Multi-Community grants: $17 million available to award Min. award amount: $500,000 Max. award amount: $2.25 million $10 million of Program funding is set aside for tribal governments. Applicants are strongly encouraged to apply early, given the first-come, first-served award process. The application portal will close at 4:59 p.m. ET on April 17, 2025; however, award funding may be committed before this date. ** Section 21205 of Division B of the Infrastructure Investment and Jobs Act (Public Law 117-58) (Rural and Tribal Infrastructure Advancement) creates a pilot program to provide grants to fund financial, technical, and legal assistance to states and rural and tribal communities.

USDA Rural Development

Grants for rural projects that finance and facilitate development of small and emerging businesses, including technical assistance, training, and revolving loan funds.

Health Resources and Services Administration

<p>The Rural Communities Opioid Response Program (RCORP) - Community Systems Development <span style="background-color:rgba(0,0,0,0);">provides funding to communities in rural areas to develop and/or expand behavioral health systems of care through formalized networks that expand operational and clinical service capacity regionally through coordinated implementation of evidence-based SUD prevention, treatment, recovery, and related services.</span></p>

Health Resources and Services Administration

The Rural Communities Opioid Response Program (RCORP) - Community Systems Development provides funding to communities in rural areas to develop and/or expand behavioral health systems of care through formalized networks that expand operational and clinical service capacity regionally through coordinated implementation of evidence-based SUD prevention, treatment, recovery, and related services.

Health Resources and Services Administration

The purpose of the Rural Communities Opioid Response Program (RCORP) - Evaluation is to evaluate the impact of rural behavioral health strategies and methods employed under the RCORP initiative, and to develop evaluation tools and resources for use in rural communities to inform future community-led rural health initiatives

Health Resources and Services Administration

<p>The purpose of the Rural Communities Opioid Response Program (RCORP) - Evaluation is to evaluate the impact of rural behavioral health strategies and methods employed under the RCORP initiative, and to develop evaluation tools and resources for use in rural communities to inform future community-led rural health initiatives</p>

USDA Rural Development

Grants and loan guarantees for rural small businesses and agricultural producers for renewable energy systems and energy efficiency improvements.

Health Resources and Services Administration

The Rural Health Network Development Planning Program supports the planning and development of rural integrated health care networks with specific focus on collaboration of entities to establish or improve local capacity and care coordination in underserved communities. Specifically, the program uses the concept of developing networks as a strategy for linking rural health care network participants together to achieve greater collective capacity to overcome local challenges, expand access and improve the quality of care in the rural communities these organizations serve. The program helps network participants work together on three legislative aims: Achieve efficiencies. Expand access to, coordinate, and improve the quality of basic health care services and associated health outcomes. Strengthen the rural health care system as a whole. The intent is that rural health networks will do the following: Expand access to care. Increase the use of health information technology. Explore alternative health care delivery models. Continue to achieve quality health care across the continuum of care.

Health Resources and Services Administration

<p>The Rural Health Network Development Planning Program supports the planning and development of rural integrated health care networks with specific focus on collaboration of entities to establish or improve local capacity and care coordination in underserved communities. Specifically, the program uses the concept of developing networks as a strategy for linking rural health care network participants together to achieve greater collective capacity to overcome local challenges, expand access and improve the quality of care in the rural communities these organizations serve. The program helps network participants work together on three legislative aims:&nbsp;</p><p>• Achieve efficiencies.&nbsp;</p><p>• Expand access to, coordinate, and improve the quality of basic health care services and associated health outcomes.&nbsp;</p><p>• Strengthen the rural health care system as a whole.&nbsp;</p><p>&nbsp;</p><p>The intent is that rural health networks will do the following:&nbsp;</p><p>• Expand access to care.&nbsp;</p><p>• Increase the use of health information technology.&nbsp;</p><p>• Explore alternative health care delivery models.&nbsp;</p><p>• Continue to achieve quality health care across the continuum of care.</p>

Health Resources and Services Administration

<p>The Rural Health Network Development program supports integrated health care networks that address health care needs of targeted rural communities.&nbsp; Applicants may choose between two funding tracts.</p><p>The <strong>Network Advancement Tract</strong> supports networks comprised of independent rural hospitals and clinics in integrated network collaboration. It bridges support to offset small scale structural barriers that make it difficult for rural providers to compete in an increasingly consolidated health care system landscape and is designed to help bring economic efficiencies to small independent rural entities by expanding and enhancing their ability to strengthen operations, preserve existing services, and build new lines of care through integrated network collaboration that preserves local autonomy.</p><p>The <strong>Network Development Tract</strong> supports nascent/early-stage integrated rural health care networks with funding to plan, develop, and carry out targeted operational or clinical service expansion activities.&nbsp; &nbsp;</p><p>Both tracts aim to expand access to care, improve coordination and quality, strengthen health outcomes, increase efficiency, and support a stronger rural health care system.</p>

Health Resources and Services Administration

The Rural Health Network Development program supports integrated health care networks that address health care needs of targeted rural communities. Applicants may choose between two funding tracts.The Network Advancement Tract supports networks comprised of independent rural hospitals and clinics in integrated network collaboration. It bridges support to offset small scale structural barriers that make it difficult for rural providers to compete in an increasingly consolidated health care system landscape and is designed to help bring economic efficiencies to small independent rural entities by expanding and enhancing their ability to strengthen operations, preserve existing services, and build new lines of care through integrated network collaboration that preserves local autonomy.The Network Development Tract supports nascent/early-stage integrated rural health care networks with funding to plan, develop, and carry out targeted operational or clinical service expansion activities. Both tracts aim to expand access to care, improve coordination and quality, strengthen health outcomes, increase efficiency, and support a stronger rural health care system.

Rural LISC

Small business support and economic development in rural areas

Rural LISC

Affordable housing development and preservation in rural communities

Transportation Department

DOT's Rural Opportunities to Use Transportation for Economic Success (ROUTES) Initiative addresses the transportation infrastructure needs of rural and Tribal communities by developing user-friendly tools and information, aggregating DOT resources, and providing direct technical assistance to connect rural and Tribal communities with the funding, financing, and outreach resources available. This notice requests comments on unmet transportation infrastructure needs in rural communities, barriers that rural communities face in addressing those needs, and opportunities for ROUTES to improve its services and technical assistance to support rural and Tribal stakeholders.

Health Resources and Services Administration

The Rural Residency Planning and Development (RRPD) program improves and expands rural health care access. It does this by developing new, accredited, sustainable rural residency programs, including rural track programs (RTPs). Newly created rural physician residency programs increase training and ultimately practice in rural areas to address physician shortages. The RRPD program provides start-up funding to create new rural residency programs in qualifying medical specialties. Long-term sustainability funding must come from viable and stable sources, such as Medicare, Medicaid, and other public or private sources. Qualifying medical specialties are:Family medicine.Internal medicine.Psychiatry.General surgery.Obstetrics and gynecology.For this notice of funding opportunity (NOFO), rural residency programs:Are accredited physician residency programs.Train residents in clinical training sites that are physically located in a rural area as defined by HRSA's Federal Office of Rural Health Policy (FORHP) for greater than 50 percent of their total time in residency.Focus on preparing physicians to practice in rural communities.

Health Resources and Services Administration

<p style="margin-left:0px;">The Rural Residency Planning and Development (RRPD) program improves and expands rural health care access. It does this by developing new, accredited, sustainable rural residency programs, including rural track programs (RTPs). Newly created rural physician residency programs increase training and ultimately practice in rural areas to address physician shortages. The RRPD program provides start-up funding to create new rural residency programs in qualifying medical specialties. Long-term sustainability funding must come from viable and stable sources, such as Medicare, Medicaid, and other public or private sources. Qualifying medical specialties are:</p><ul style="margin-left:0px;"><li data-list-item-id="efa87dc46f6493c28c743558e89004495">Family medicine.</li><li data-list-item-id="ea5be0921534e23ce7e16adc327e7d607">Internal medicine.</li><li data-list-item-id="e1150283fca8ca0d71cd90d1ef1ec63ea">Psychiatry.</li><li data-list-item-id="e8509bcaeb6836b023540cb83c478a660">General surgery.</li><li data-list-item-id="e200c6f2e35d1eb327cbf5ad8a912c892">Obstetrics and gynecology.</li></ul><p style="margin-left:0px;">For this notice of funding opportunity (NOFO), rural residency programs:</p><ul style="margin-left:0px;"><li data-list-item-id="e99eb21d89704f93a4e43339be3341487">Are accredited physician residency programs.</li><li data-list-item-id="eb7c3dde2b6c4ec3bba26a6098bd8b011">Train residents in clinical training sites that are physically located in a rural area as defined by <a href="https://data.hrsa.gov/topics/rural-health/rural-health-eligibility"><u>HRSA's Federal Office of Rural Health Policy (FORHP)</u></a> for greater than 50 percent of their total time in residency.</li><li data-list-item-id="efb82c8640a039596a254a421db502302">Focus on preparing physicians to practice in rural communities.&nbsp;</li></ul>

Rural School and Community Trust

Leadership development for rural educators and community leaders

NIMH - National Institute of Mental Health

Approximately 4.5 million children in the United States (US) display severe emotional and behavioral disturbance. While it is not unusual for preschoolers to have occasional temper tantrums, it is considered symptomatic when temper outbursts (characterized by sudden, violent expression of strong feeling, anger, and aggression) occur most days that are severe enough to impair their academic, social, and family functioning. Evidence-based therapies such as parent child interaction therapy (PCIT) reduce behavioral challenges in children by improving parent-child relationships through parenting practices taught over a multi-week period. Despite the widespread availability of behavioral interventions, there are significant challenges: (a) the effectiveness of interventions is contingent upon parents remembering parenting practices taught during weekly therapy sessions to engage with their children, (b) there is limited education for affected children and their parents to help preempt temper outbursts and regulate their emotion, and (c) families from rural areas and populations with limited specialized pediatric mental health providers are less likely to have access to and utilize evidence-based therapies when it is available. The overarching goal of this convergent research proposal is to investigate the development of generative methods with closed-loop feedback from parents to individualize real-time interventions for children when a temper outburst is predicted. The project will accomplish the goal through the following aims. Aim 1: This project will develop generative algorithms with closed-loop feedback using 5.4 million minutes of smartwatch data collected from 50 children (aged 3 – 7 years) and parent-provided timestamps (closed-loop feedback) of disruptive behavior (characterized by temper outbursts). Aim 2: The developed technology will then be evaluated in a cohort of 50 new children to assess if parenting practices combined with child-initiated mindfulness (i.e., new patient-education) upon a predicted temper outburst could improve behavioral outcomes. Aim 3: Elucidate the perspectives of stakeholders (e.g., parents, schoolteachers) on the use of continuous monitoring devices for adaptive generative intelligence algorithms.

National Park Service

This announcement is to provide public notice of the National Park Service (NPS), intention to fund the following project with University of Alaska Anchorage under a Cooperative Ecosystem Studies Unit (CESU) program. CESUs are partnerships that provide research, technical assistance, and education. The project intended award is $33,926. STATUTORY AUTHORITY: Agreements Concerning Cooperative Research and Training on NPS Resources (16 U.S.C. 1a-2(j)): The Secretary may enter into agreements with public or private educational institutions, States and their political subdivisions, for the purpose of developing adequate, coordinated, cooperative research and training programs concerning the resources of the National Park System, and pursuant to such agreements, to accept from and make available to the cooperator such technical and support staff, financial assistance for mutually agreed upon research projects, supplies and equipment, facilities, and administrative services relating to cooperative research units as the Secretary deems appropriate. STATEMENT OF JOINT OBJECTIVES/PROJECT MANAGEMENT PLAN: Project Description This is a collaborative effort between UAA and NPS to assess important staging areas in Bering Land Bridge National Preserve (BELA) and Cape Krusenstern National Monument (CAKR) for post-breeding shorebirds and to communicate the findings of this effort to the local community, park visitors, and international communities. This project builds on existing research by Federal, State, local and international partners to pursue the global objective of addressing the effects of climate changes on wildlife. Phase 1) Plan survey design and logistics. During spring 2014, UAA will complete the NPS Research Compliance and Permit Process and will obtain the necessary permits for conducting low-level aerial surveys. UAA will schedule pilots to conduct surveys and will consult with local native/tribal groups about this project. Phase 2). Conduct aerial surveys. During two, one-week periods in late-July and early August 2014, coinciding with peak shorebird use, Dr. Taylor (UAA) will conduct low-level aerial surveys of transects. Phase 3) Summarize and communicate findings. Dr. Taylor (UAA) will summarize results of these surveys in a detailed technical report to be completed in spring 2015. This report will include a map showing spatial variation in post-breeding shorebird use across WEAR littoral habitats. It will also include site-specific estimates of shorebird use, tables detailing species composition, and figures describing migration phenology. Dr. Taylor (UAA) will deliver an oral presentation that summarizes this study to park managers and meet with park interpretative staff in Kotzebue. Public Purpose This project allows for facilitating partnership opportunities with neighboring countries (specifically Canada, Mexico, and neighboring Pacific Islands), and building sister park relationships throughout the Pacific and Arctic Oceans to enhance marine resource conservation and education of the public's natural resources. Dr. Audrey Taylor (UAA) is well connected with both Alaskan and Russian members of Beringia's shorebird research community and actively engages in partnerships, which address circumpolar and regional issues that affect shorebird conservation. These national and international level relationships will be critical for developing and implementing park-based shorebird conservation and management activities. Communicating the status of migratory birds to the public is crucial to local and international conservation efforts. Migratory birds offer a unique platform for conveying the concept of ecological connectivity across international boundaries. In this way, shorebirds provide educational opportunities that can connect youth in rural Alaskan communities to each other and to youth in Beringia and Asia and Central/South America. Using an existing and nationally recognized educational program about bird species of concern in northern Alaska (12 Species of Concern Program, delivered annually in schools in Anaktuvuk Pass and Fairbanks), the UAA and park interpretative staff will integrate shorebirds and these research activities into the curriculum for all communities neighboring BELA and CAKR. Similarly, the information from this project will be incorporated in an existing web-based educational program (developed in part by the P.I.) on western sandpipers, which is available to the public. The partner, in cooperation with the National Park Service will: 1. Provide a technical report detailing spatial variation in post-breeding shorebird use in WEAR littoral habitats. Provide a one-page, resource brief summary. 2. Provide regionally specific and relevant shorebird information to supplement the curriculum for the 12 Species of Concern Program (NPS, K-12 program delivered annually in schools in Anaktuvuk Pass and Fairbanks) to include shorebirds and the concept of pre-migratory staging in the life cycle of migratory birds. 3. UAA will complete the NPS Research Compliance and Permit Process and will obtain the necessary permits for conducting low-level aerial surveys. UAA will schedule pilots to conduct surveys and will consult with local native/tribal groups about this project. 4. Conduct low-level aerial surveys of transects. 5. Dr. Taylor (UAA) will deliver an oral presentation that summarizes this study to park managers, schools, and communities, and will summarize results of the surveys in a detailed technical report. NATIONAL PARK SERVICE INVOLVEMENT -Substantial Involvement : 1. Provide financial assistance to UAA in the amount of $33,926 for the project scope of work. 2. Assign (Lois DalleMolle) as the Agreement Technical Representative (ATR). 3. Provide additional technical assistance will the project by NPS staff Jeremy Mizel and Stacia Backensto (Arctic Network I&amp;M (ARCN) Wildlife Biologists). 4. Coordinating aerial survey plan and use of NPS housing in Kotzebue. This will be completed by June, 1 2014. 5. Transfer of information to Dr. Taylor gathered from related and ongoing work concerning shorebirds in this area. This is ongoing throughout the course of this project. 6. Assist with design and completion of a resource brief for park managers, schools, and communities. This assistance will occur during October and November 2014. 7. Facilitate information transfer between Dr. Taylor and NPS interpretive staff and collaborate with Dr. Taylor and park interpretive staff to develop these portions of bird migration and species of concern curriculum for its delivery to schools in northwestern Alaska. This assistance will occur during October and November 2014. 8. Review of the aerial survey report by Jeremy Mizel (ARCN Wildlife Biologist) to be completed by May 1, 2015. 9. Provide assistance with survey design, analysis, map creation in GIS, and report writing. SINGLE-SOURCE JUSTIFICATION: Department of the Interior Policy (505 DM 2) requires a written justification which explains why competition is not practicable for each single-source award . The National Park Service did not solicit full and open competition for this award based the following criteria: (4) Unique Qualifications- Dr. Taylor is uniquely qualified to perform the activity based upon technical expertise and scholarship in addition to her partnerships and commitment to conservation of Beringia s shorebird research community. Dr. Taylor s prior work, using the same methods, on the North Slope of Alaska to document shorebird use of coastal habitat was fundamental in defining important shorebird habitat for the final IPA/EIS NPR-A document. These well-tested methods will be used to develop management plans for shorebirds in Bering Land Bridge National Preserve and Cape Krusenstern National Monument. Technical contact information: Lois DalleMolle, lois_dalle-molle@nps.gov, 907-455-0635 National Park Service, Alaska Region. End of FOA

Agriculture Department

The Rural Housing Service (RHS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA), is issuing this notice to announce a pilot for the Single Family Housing Section 502 direct loan program (Section 502) to test alternative values of modest housing for self-help housing and when affordable housing products are provided. The Agency intends to evaluate the impact of authorizing the value of properties constructed through the self-help program to exceed the maximum area loan limit under RHS's current regulations; and permitting grants and other affordable housing products to exceed the area loan limit for all Section 502 loans. This notice outlines the pilot parameters and provides contact information for additional details about the pilot.