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24 grants worth up to $78.2M match your search

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Imaging-Enabled Flow Cytometry for Enhancing Extracellular Vesicle, Lipid Nanoparticle, and Cell Morphology Characterization

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NIGMS - National Institute of General Medical Sciences

PROJECT SUMMARY Researchers at the University of Puerto Rico–Mayagüez (UPRM) request support to acquire the Attune CytPix Flow Cytometer. This high-performance instrument uniquely integrates bright-field imaging with multiparameter flow cytometry for real-time, high-throughput analysis of cells and nanoscale particles. Equipped with two excitation lasers (405 nm and 488 nm) and supporting future upgrades, the system also includes a small particle detector with optimized filters for analyzing particles as small as 100 nm, and an autosampler for high-throughput evaluation of multiple specimens. It enables the simultaneous collection of fluorescence signals and label-free bright-field images, providing over 25 morphological parameters that enhance gating, quality control, and data interpretation. This capability is essential for characterizing extracellular vesicles (EVs), lipid nanoparticles (LNPs), and cellular phenotypes in response to environmental and therapeutic stimuli. The instrument addresses three pressing gaps in UPRM’s infrastructure: (1) the absence of a cytometer capable of resolving and validating small particles with image-based analysis; (2) the lack of integrated systems that support real-time morphology assessment and computational modeling; and (3) the reliance on a single aging cytometer with limited resolution, throughput, and access. The Attune CytPix will support NIH- and NSF-funded research spanning regenerative medicine, cancer biology, cell manufacturing, and nanomedicine, including projects led by Dr. Camilo Mora (mid-career), Dr. Maribella Domenech (established), Dr. Claribel Acevedo (established), Dr. Jose Carmona (early-career), and Dr. Michael Álvarez (early-career). The proposal strengthens interdepartmental and intercampus collaboration by enabling coordinated experimentation and data sharing between research groups in Engineering, Bioengineering, Chemistry, Biology at UPRM, and Computer Science at UPR–Rio Piedras. The instrument will be housed in a dedicated BSL-2 core facility in the Department of Chemical Engineering and will be co-managed by Drs. Mora and Domenech, who bring complementary expertise in flow cytometry, bioimaging, and EV-based applications. Dr. Domenech, with a strong track record in flow cytometry experimental design and user training, will work alongside Dr. Mora to lead user onboarding, ensure data quality, and maintain the operational continuity of the system. The instrument will also serve as a training platform for undergraduate and graduate students engaged in bioprocessing, biosensing, and advanced cytometry, with integration into research-based coursework and lab-based instruction. It will be a key resource for researchers and students in Engineering, Biotechnology, Bioengineering, Chemistry, and related fields at the University of Puerto Rico, a leading STEM- focused institution and a key contributor to the national scientific workforce. The Attune CytPix will significantly enhance UPRM’s biomedical research capacity, enable high-resolution particle and cell analysis, and support the long-term development of a technically skilled research workforce in our jurisdiction.

Up to $249K
2027-08-04
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Implementation of a culturally adapted alcohol screening, brief intervention and referral to treatment (SBIRT) program in Cameroon.

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FIC - John E. Fogarty International Center for Advanced Study in the Health Sciences

Alcohol use is a major contributor to injury burden worldwide and remains an important public health challenge in the United States (US), particularly in underserved regions with limited access to trauma and behavioral health services. Cameroon, like other Sub-Saharan African countries, is disproportionately affected by alcohol- related injuries (ARIs), with higher injury burden and alcohol consumption than neighboring countries. Similar barriers to integrating alcohol use disorder (AUD) interventions into trauma care also persist in low-resource trauma settings in the US, where workforce shortages and constrained trauma systems limit delivery of evidence-based AUD care. As involvement in an ARI significantly increases the risk of subsequent ARIs, failure to address AUD in injured patients currently represents a missed opportunity for both AUD treatment and injury prevention. The Screening, Brief Intervention, and Referral to Treatment (SBIRT) model is an evidence-based intervention used in emergency departments (EDs) in high-income countries, including the US, to identify and address AUD. However, implementation of SBIRT remains inconsistent in US resource- limited trauma settings due to staffing, workflow, and infrastructure barriers. Cameroon provides a unique opportunity to evaluate scalable SBIRT implementation strategies in a severely resource-constrained trauma system where AUD services are limited but where strong trauma research infrastructure and pilot data already exist. The long-term goal of this project is to reduce the burden of ARIs by leveraging research infrastructure in Cameroon to develop scalable evidence-based models for integrating AUD interventions into trauma systems. The overall objective is to evaluate the feasibility and effectiveness of a Cameroon-adapted SBIRT intervention in the ED setting. We hypothesize that the adapted SBIRT intervention will significantly reduce hazardous alcohol use among trauma patients. To achieve this objective, the study will pursue three aims: 1) train ED healthcare providers on a Cameroon-adapted SBIRT program; 2) evaluate feasibility, acceptability, and fidelity of SBIRT implementation in the Cameroonian ED context; and 3) evaluate effectiveness of SBIRT implementation in reducing hazardous drinking behaviors and PEth biomarker levels. This study will leverage implementation science methods to evaluate real-world implementation and scalability of SBIRT in a resource- constrained trauma system. Findings from this work may inform scalable implementation approaches for underserved trauma settings in the US, including rural hospitals and trauma deserts with limited access to integrated AUD care, while also supporting broader implementation across low-resource settings globally.

Up to $87K
2031-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Implementation Science and Partnerships Advancing Care and Training in Mental Health (IMPACT- MH) T32 Postdoctoral Fellowship

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NIMH - National Institute of Mental Health

Mental health (MH) disorders affect over 970 and 59.3 million people worldwide and the U.S, respectively, and remain the leading cause of disease burden across the lifespan, driving significant disability, premature mortality, and elevated risk for comorbid physical health conditions and a staggering national economic impact. Despite decades of research, the burden has not measurably decreased since 1990. In the U.S., nearly half of individuals with mental illness and over 70% with substance use disorders do not receive adequate care. Structural obstacles—including workforce shortages, high costs, negative attitudes, and fragmented care systems—continue to impede access. Implementation Science (IS) offers vital evidence-based approaches to close the persistent gap between evidence-based MH research and routine practice, yet few proven interventions have been scaled successfully to benefit large populations. The IMPACT-MH T32 Training Program (Implementation Science and Partnerships Advancing Care and Training in Mental Health) seeks to cultivate the next generation of MH IS researchers committed to sustainably reducing the U.S. treatment gap. Postdoctoral fellows will engage in intensive mentorship and a fully integrated curriculum spanning all research phases: pre-intervention design, intervention delivery, and post-implementation evaluation. Early emphasis on sustainability and partnerships with communities and policymakers will inform design choices—ensuring that interventions can be effectively delivered, scaled up, and rigorously evaluated over time. Training domains include deployment-focused research—contextual adaptation and stakeholder co-design of evidence-based interventions (EBI) across varied settings—and dissemination, implementation, scale-up, and policy research aimed at securing sustainable MH services. Through tailored mentorship and collaborative training with faculty experts in public health, psychology/psychiatry, IS, and health policy, fellows will develop the interdisciplinary perspectives and the conceptual, methodological, and technological competencies necessary to advance MH IS research. Mentored by experienced faculty, a cohort of four fellows, appointed for two to three years, will partner with communities and policymakers to design projects and pursue competitive NIH awards (including K-series and R-series proposals) will enhance the relevance, feasibility, and impact of their research. Leveraging well-established multisectoral partnerships with community service organizations, health networks, faith-based coalitions, and government programs, IMPACT-MH T32 ensures that fellows’ research informs real-world services and policy. Graduates of IMPACT-MH will be equipped to translate emerging discoveries into sustainable, evidence-informed mental health care systems and policies that strengthen the public health impact of NIMH-supported research (NIMH objective). By training leaders, fostering cross-disciplinary collaboration, building multi-sector partnerships, tailoring and scaling EBI, and advancing sustainable solutions, this program will make significant strides toward closing the U.S. mental health treatment and research gap.

Up to $269K
2031-04-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Initiative for Maximizing Student Development (IMSD) (T32) at Rutgers University-Newark

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NIGMS - National Institute of General Medical Sciences

PROJECT SUMMARY The mission of the proposed IMSD Program is to increase the number of PhDs underrepresented in the diverse fields of Biology, Chemistry, Earth and Environmental Sciences, Neuroscience and Psychology who will proceed to postdoctoral research fellowships/positions, on a trajectory to enter the biomedical/behavioral research workforce. To accomplish this goal, our main program objectives are: 1) to foster in each of our IMSD trainees, efficacy in their chosen specialty, self- identification as a research scientist, and the self-confidence that they are integral, contributing members of their scientific community; 2) to develop our trainees’ technical and professional skills required to conduct research in an ethically responsible and rigorous manner; 3) to provide didactic, research, mentoring, and career development elements in preparation for a biomedical/behavioral research career; 4) to promote our trainees’ timely fulfillment of the institutional requirements for the Ph.D.; 5) to foster and facilitate every IMSD trainees’ appointment to a postdoctoral or scientific position in their specialty. The rationale for the current proposal is to build on the success of our prior IMSD/G-RISE training programs (33 PhDs in the last 15 years) and establish a new IMSD program that will seek to enrich and broaden training opportunities and diverse representation in biomedical sciences. A total of 10 students, primarily in their first years of graduate training, will be recruited from a broad pool of candidates. The following key activities comprise part of the design of the proposed IMSD Program: 1) Research Communication Workshop to develop the trainees’ skills in communicating their scientific research to a multidisciplinary audience, 2) Fellowship Writing Workshop to foster a knowledge base to develop a fellowship application, 3) Research Career Preparation seminar series and 4) Responsible Conduct of Research and Research Reproducibility seminar series. A mentor- training component is included in the proposed IMSD program with a balance between established and early career investigators. The proposed program measurable outcomes are: 1) Earning the PhD degree; 2) Applying for at least one predoctoral fellowship, 3) Successfully vying for a postdoctoral position or related biomedical position by the completion of the doctorate. Taken together, the proposed IMSD Program will continue the development of a successful training program aimed at fostering the entrance of the trainees into fields of behavioral/biomedical research in which they have been traditionally underrepresented.

Up to $581K
2031-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Innovations in Graduate Education (IGE) Program

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U.S. National Science Foundation

The Innovations in Graduate Education (IGE) Program is designed to encourage development and implementation of bold, new, and potentially transformative approaches to STEM graduate education training. The program seeks proposals that a) explore ways forgraduate students in STEM master s and doctoral degree programs to develop the skills, knowledge, and competencies needed to pursue a range of STEM careers, or b) support research on the graduate education system and outcomes of systemic interventions and policies. IGE projects are intendedto generate the knowledge required for the customization, implementation, and broader adoption of potentially transformative approaches to graduate education. The program supports piloting, testing, and validating novel models or activities and examining systemic innovations with high potential to enrich and extend the knowledge base on effective graduate education approaches. The program addresses both workforce development, emphasizing broad participation, and institutional capacity-building needs in graduate education. Strategic collaborations with the private sector, non-governmental organizations (NGOs), government agencies, national laboratories, field stations, teaching and learning centers, informal science organizations, and academic partners are encouraged.

$300K – $1M
2027-03-25
sciencetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription

Innovative Water Infrastructure Workforce Development Grant

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Environmental Protection Agency

The U.S. Environmental Protection Agency (EPA) is soliciting applications under the authority of the Safe Drinking Water Act (SDWA) section 1459E to accelerate career pipelines in the water utilities sector and provide access to water utility workforce opportunities. This action advances the Administration s priorities, including the goals of Make America Healthy Again, by focusing on building the nation s water workforce which is critical to ensuring public health and environment protection. Consistent with the law, this action will help inform people about the role of water and wastewater utilities in their communities and increase the awareness of water utility career opportunities.The purpose of this funding opportunity is to support expanding career opportunities in the drinking water and wastewater utility sector and elevating public awareness about jobs in the water workforce. Eligible applicants under this funding opportunity are Institutions of Higher Education (IHEs), nonprofit organizations, and public works departments and agencies. Eligible activities include apprenticeship and internship programs, education programs designed for elementary, secondary, and higher education students, regional industry collaborations, and training programs designed to support decentralized workforce. Efforts should aim for measurable results and clearly show tangible benefits for water systems and communities. The proposed activities support the Agency s Powering the Great American Comeback Initiative s Pillar 1: Clean Air, Land, and Water for Every American. Examples include training individuals through an apprenticeship program and placing them into water sector jobs, training individuals for industry accreditation, and developing collaborations with community colleges, technical schools, utilities to address the water utility employment needs.

Up to $7.8M
2026-10-05
Education

Free to search & build · $99 one-time to unlock the application pack · No subscription

Institutional Clinical and Translational Science Award

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NCATS - National Center for Advancing Translational Sciences

PROJECT SUMMARY The Penn-CHOP Clinical and Translational Science Award (CTSA) Hub proposes a transformative vision to catalyze a dynamic clinical and translational science (CTS) ecosystem that accelerates the delivery of innovative, life-altering therapies to individuals across the lifespan. Aligned with the NCATS mission to bring more treatments to all people more quickly, our Hub will leverage its nationally-recognized strengths in translational therapeutics, data science, community engagement, and workforce development to advance the science and practice of clinical translation. We propose four integrated aims: (1) Innovate novel approaches to advancing the development and dissemination of translational therapeutics; (2) Accelerate the application of state-of-the-art data science resources and dynamic data ecosystems to enable a Penn-CHOP academic learning health system (aLHS) framework and catalyze groundbreaking CTS; (3) Integrate our Hub with our communities and stakeholders to promote community-partnered and collaborative research within families and across the lifespan; (4) Educate, train, advance, and retain a skilled multidisciplinary workforce ready to meet the demand of an ever-evolving CTS and and CTR landscape. Our Hub will serve as a national model for integrated, community-engaged, and data-driven translational science. Through rigorous evaluation, continuous quality improvement, and dissemination of best practices, we aim to contribute meaningfully to the CTSA consortium's collective impact on public health.

Up to $10.8M
2033-05-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)

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National Institutes of Health

Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has incorporated additional flexibilities for institutional training programs serving the mission interests of non-malignant kidney, urologic, and hematologic diseases, encompassing both adult and pediatric conditions. The purpose of this notice of funding opportunity is to invite applications for Institutional Network Awards (U2C-TL1) to recruit, train, and retain the next generation of researchers and provide them with the coordinated support, resources, and networks they need to succeed and lead. To maximize integration and promote a highly connected trainee community, institutions are invited to submit a single, unified U2C-TL1 application. Representation across all kidney, urologic, and hematologic disciplines is not expected or required. If feasible, applications may include multiple departments within and across institutions. It is expected that each U2C-TL1 award will actively participate in the Kidney, Urology and Hematology Research-Training Network (KUHR-TN), a nationwide coalition of individual U2C-TL1 awards.

Up to $2.1M
2028-05-26
Health

Free to search & build · $99 one-time to unlock the application pack · No subscription

Institutional Network Award for Promoting Kidney, Urologic, and Hematologic Research Training (U2C - Clinical Trial Not Allowed)

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National Institutes of Health

Responding to the needs of the scientific community to bolster a vibrant and sustainable research workforce, the Division of Kidney, Urologic, and Hematologic Diseases (KUH) at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) has incorporated additional flexibilities for institutional training programs serving the mission interests of non-malignant kidney, urologic, and hematologic diseases, encompassing both adult and pediatric conditions. The purpose of this notice of funding opportunity is to invite applications for Institutional Network Awards (U2C-TL1) to recruit, train, and retain the next generation of researchers and provide them with the coordinated support, resources, and networks they need to succeed and lead. To maximize integration and promote a highly connected trainee community, institutions are invited to submit a single, unified U2C-TL1 application. Representation across all kidney, urologic, and hematologic disciplines is not expected or required. If feasible, applications may include multiple departments within and across institutions. It is expected that each U2C-TL1 award will actively participate in the Kidney, Urology and Hematology Research-Training Network (KUHR-TN), a nationwide coalition of individual U2C-TL1 awards.

Up to $2.1M
2028-05-26
Healthhealthcare

Free to search & build · $99 one-time to unlock the application pack · No subscription

Interdisciplinary Cellular and Biomolecular Dynamics Training and Education Program (InCuBaTE)

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NIGMS - National Institute of General Medical Sciences

We propose a graduate research training program in Interdisciplinary Cellular and Biomolecular Dynamics Training and Education Program (InCuBaTE) at the University of California Merced, the 10th campus of the UC system that opened in 2005. The major objective of this program is the establishment of a doctoral level graduate training program at UC Merced in the biomedical sciences to train cohorts of sixteen predoctoral students (8/yr, appointed to 2 year terms) to identify and solve pressing biological problems involving cellular and biomolecular dynamics using quantitative interdisciplinary approaches that prepare them for competitive careers in the biomedical field. Transformative advances in the biomedical research arena increasingly require contributions from many different fields and InCuBaTE leverages the uniquely interdisciplinary structure at UCM, to join faculty from six different departments forming a vibrant, interdisciplinary research community with a common vision for research and education. Because UCM is still in its developmental stages, an initiative like InCuBaTE can have a truly transformative impact by establishing a nucleus of high-quality training and research on campus. As part of the program, we will establish an IBST designated emphasis (a graduate minor) open to all graduate students in science and engineering who participate in the new coursework we are developing, thus enhancing the overall graduate training offerings on campus. Opening a training program for the highly skilled biomedical research workforce of tomorrow at UC Merced will also have an enormous impact on the region, producing a cohort of trained professionals that will raise the economic and educational standards of the surrounding educationally and economically disadvantaged communities. The specific objectives of our program are (i) to increase opportunities for all Americans to pursue biomedical training (ii) to ensure retention and speed up the time to degree (iii) to produce graduates with a broad training in an interdisciplinary curriculum for biomedical sciences (iv) to inculcate a sense of belonging and teamwork skills and (v) to ensure successful transition into the biomedical research workforce. There are many unique aspects of our proposed program that specifically address these objectives including the quality, size and breadth of the applicant pool that we target, a core interdisciplinary curriculum of courses, a summer bridge program that addresses retention by bringing students out two months before classes and immersing them in hands-on training, mentoring and professional development such as fellowship proposal writing, an interdisciplinary multiple mentor structure and a unique career development program that focuses on specific skills that are important in the biomedical research workforce but are commonly not addressed in such training programs - business/entrepreneurial skills and science communication skills.

Up to $896K
2031-06-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

International Research Experiences for Students

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U.S. National Science Foundation

The International Research Experiences for Students (IRES) program supports international research and research-related activities for U.S. science and engineering students. The IRES program contributes to development of a diverse, globally engaged workforce with world-class skills. IRES focuses on active research participation by undergraduate and/or graduate students in high quality international research, education and professional development experiences in NSF-funded research areas. The overarching, long-term goals of the IRES program are to enhance U.S. leadership in science and engineering research and education and to strengthen economic competitiveness through training the next generation of science research leaders. IRES focuses on the development of a world-class U.S. STEM workforce through international research experiences for cohorts of U.S. students. Student participants supported by IRES funds must be citizens, nationals, or permanent residents of the United States. Students do not apply directly to NSF to participate in IRES activities. Students apply to NSF-funded investigators who receive IRES awards. To identify appropriate IRES projects, students should consult the directory of active IRES awards. All PIs, co-PIs and Senior Personnel on IRES proposals must be from U.S. based organizations. Personnel from international partners should be listed as "non-NSF funded collaborators." Guidance on information to provide for "non-NSF funded collaborators" is found in Section V.A. IRES projects engage a group of undergraduate and/or graduate students in active high-quality collaborative research, in principle at an international site with mentorship from international researchers. IRES projects must be organized around a coherent overarching intellectual theme that may involve a single discipline or multiple disciplines funded by NSF. For all IRES proposals, PIs are strongly encouraged to outline a variety of virtual, hybrid or other alternative approaches to strengthen and maintain international collaboration in addition to travel. It is expected that these approaches will extend collaboration beyond the actual international trip and strengthen IRES proposals overall.

rolling
sciencetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription

International Society for Environmental Epidemiology (ISEE) North American Chapter (NAC) 2026 Regional Conference

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NIEHS - National Institute of Environmental Health Sciences

ABSTRACT/PROJECT SUMMARY The International Society for Environmental Epidemiology (ISEE) North America Chapter (NAC) was formed in 2019 focusing on promoting research collaborations across North American institutions. Since then, it has grown to host 1055 members from or residing in the United States (US), Bermuda, Canada, and Greenland. Although ISEE Global hosts an annual international meeting, this meeting is held on different continents each year, and visa issues and travel expenses often inhibit attendance by students, trainees, and early career researchers. Therefore, the ISEE-NAC started hosting regional meetings in 2023 to accommodate members with barriers to attending the global meeting when the location is not in America. Given the success of our previous regional meeting, recent changes in institutional funding allocation, and travel restrictions for international students and trainees and federal employees, we have experienced an increased interest in hosting the ISEE-NAC meeting in 2026. This meeting will enhance the mission of ISEE-NAC by providing a venue for environmental health and epidemiologic researchers, practitioners, and government personnel located in North America to network with potential new collaborators. The 2026 ISEE-NAC regional meeting will be held with a theme of “translating environmental health research to inform public health practice” and will be critical to moving our field forward. Meeting planning is already underway. Together with the organizing committee, we are planning a 2.5 day in-person meeting in Baltimore, MD (June 1-4, 2026) at the Johns Hopkins University Homewood Campus. The purpose of this meeting is to: provide networking and professional development opportunities for students, trainees, and early career scientists in environmental epidemiology (Aim 1); illuminate environmental epidemiology research throughout North America (Aim 2); and highlight research related to environmental health and epidemiology intervention, translational research, and community engagement (Aim 3). By focusing on community engagement, translation, and implementation, this meeting supports NIEHS Strategic Plan 2025-2029 items related to solutions-focused research and translation, building collaboration and partnership, and supporting training and workforce development through increasing public access to important environmental health findings.

Up to $25K
2027-03-31
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

Labor Market Supply and Demand in the Northern Triangle: Leveraging Data to Build an Efficient Labor Market

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Bureau of International Labor Affairs

NOTE: This is a Notice of Intent. An announcement is not related to this notice. We are not accepting applications at this time. Subject to the availability of funds, USDOL s Bureau of International Labor Affairs (ILAB) intends to award, through a competitive process, one or more cooperative agreements to organizations to achieve the following outcomes: 1) LMI systems enable educational and workforce training providers to help job-seekers and youth develop in-demand job skills, 2) LMI systems help businesses more easily identify and hire qualified workers, and 3) LMI systems enable governments to craft effective labor market policies. The project will also support the LMI systems generate data that are comparable across all three countries. The Employment and Training Administration (ETA) s Office of Grants Management anticipates publishing a Funding Opportunity Announcement (FOA) around June 2017 (the timing is subject to change). Please refer to: http://www.dol.gov/ilab/grants/ and https://www.dol.gov/agencies/ilab/resources/grants for general guidelines and examples of previous cooperative agreement applications. This notice does not include an FOA or any attachments. It only constitutes a notice of USDOL s intent to publish an FOA at a later date. Interested applicants are encouraged to monitor www.grants.gov for the FOA because, if an FOA is published, grants.gov is the method by which the FOA will be made available to the public. No email or paper copies of any FOA will be provided.

$4M
rolling
other

Free to search & build · $99 one-time to unlock the application pack · No subscription

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