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Town of Cortlandville

open

Cortlandville

Small Business

Up to $70K
Rolling
general

Free to search & build · $99 one-time to unlock the application pack · No subscription

Town of Hamden

open

Hamden

Small Business

Up to $62K
Rolling
general

Free to search & build · $99 one-time to unlock the application pack · No subscription

Town of Queensbury

open

Queensbury

Small Business

Up to $60K
Rolling
general

Free to search & build · $99 one-time to unlock the application pack · No subscription

Translation of flexSTIM: a biomimetic implanted pattern generator for effective long-term pressure injury prevention through automated weightshifting and enhanced tissue health.

open

NIH

Pressure injury (PrI) prevention remains a major challenge over the long term for Veterans with impaired mobility, in particular those with spinal cord injury (SCI). PrI limit activities of daily living, often leading to prolonged bedrest, hospitalization and even death. Clinical practice guidelines recommend weight-shifting every 20 minutes for persons with SCI, which is impractical when busy with activities of daily living. We have previously shown that long term use of dynamic gluteal intermittent stimulation (iGSTIM) using percutaneous electrodes and an external stimulator effectively provides an extra means of weight shifting, improves local blood flow, increases muscle size and reduces the incidence of tissue breakdown, specifically pressure injuries. User feedback was that long-term use of iGSTIM meant they no longer worried about recurrent skin problems requiring significant periods of bedrest. Furthermore, daily use of the system was easy and fit well in to their activities of daily living. However, continued usage is necessary to sustain improvements in tissue health and the need to keep percutaneous lead exit sites covered and regularly cleaned became arduous over time. Users requested a fully implanted iGSTIM for regular weight shifting and PrI prevention. Our team has been contacted many times over the years by individuals asking for a system that could be entirely implanted. Other prevention methods these individuals tried have failed and they are desperate for a new alternative. We have therefore developed the flexSTIM biomimetic implantable pattern generator (IPG). Prior funding synergized recent advances in flexible hybrid electronics, additive manufacturing and packaging with our prior clinical findings to provide initial development and testing of the flexSTIM IPG laying the foundation for translation and clinical implementation in persons with SCI. Combined with industry-standard intramuscular (IM) electrodes, the VA-patented flexSTIM Class III IPG is a novel technology that proactively addresses the issues of decreased muscle quality and the long-term need for regular weight-shifting for persons with limited mobility, in particular Veterans with SCI. This small flexible 2-4 channel system meets the end user need for straightforward automated weight-shifting and can be initiated daily at the touch of a button. The flexSTIM IPG is designed to be inserted into a subcutaneous pocket through a 1” incision, with the whole iGSTIM system implemented as an outpatient procedure. The complete iGSTIM system comprises the implanted battery-free flexSTIM IPG and IM electrodes, together with an external radio frequency coil and telemetry controller. The goals of this milestone driven project are to complete all pre-clinical testing required to obtain a full Investigational Device Exemption (IDE). Benchtop testing and GLP preclinical biocompatibility testing to ISO 10993 standards will be initiated during the first year of the project. Long-term in-vivo testing of the iGSTIM system's function, reliability and safety will also take place based on FDA guidance. Successful completion of preclinical testing will provide the foundation for our full IDE submission to enable an early feasibility study in 10 Veterans with SCI. The conditionally approved IRB protocol proposed under the full IDE will be reviewed by the FDA. All project activities will be milestone driven using robust and clear quantitative decision criteria and includes pivot points if needed. Project milestones include further meetings with the FDA during as needed as the project proceeds. All activities proposed for this project will be within the intended scope of providing support for technical and regulatory assistance not typically supported by other VA award mechanisms. The fully implanted iGSTIM system has enormous potential to enhance health and quality of life for Veterans with SCI.

2030-06-30
health research

Free to search & build · $99 one-time to unlock the application pack · No subscription

U.S. Embassy Praia Ambassador s Special Self-Help (SSH) Program

open

U.S. Mission to Cape Verde

U.S. Embassy Praia welcomes the submission of project applications for funding through the Ambassador s Special Self-Help Program (SSH). If interested, please carefully review the instructions below. The SSH is a grass-roots grant assistance program that allows U.S. Ambassadors to support local requests for small community-based development projects. The purpose of the Special Self-Help Program is to support communities through modest grants that will positively impact local communities. The SSH philosophy is to help communities help themselves. Projects submitted for SSH must align with one or more U.S. Embassy priorities: Economic diversification, including small business creation and income generation Projects must aim to 1) generate sustainable income and employment opportunities in local communities, 2) advance economic diversification and encourage use of local natural resources or income generation, 3) promote a culture of entrepreneurship, and/or 4) improve economic or living conditions of a community. Women start-ups and women entrepreneurs Eligible projects assist women who are launching a business or who are overseeing the early stages of business development (between one to two years). Such projects must promote a culture of women-led entrepreneurship and innovation that can be replicated in the community. Projects must also promote profitable businesses that generate revenue and benefit the community. Social and economic inclusion and creation of opportunities Projects in this category must assist youth, children, women (particularly female heads of household), and other vulnerable groups to gain access to basic services (for example water, sanitation, and primary/pre-K education). They can also assist the creation of opportunities for vulnerable groups, particularly employment for youth. Environmental protection, sustainability, resilience to environmental vulnerabilities, and adaptation to environmental change Eligible projects will increase the capacity of communities to cope with vulnerability to drought and other environmental changes by building resilience, increasing capacity to adapt, and promoting income-generating activities. For example, projects may involve activities to improve water management, diversify agricultural practices, or provide benefits to the environment. Local Community Involvement: Local involvement of the organization or group must be at least 10% in cash or in kind of the total project costs. The community contribution of funding may be crucial to make a choice between two viable requestors. In-kind contributions could be: labor (wages of masons and workers), food, accommodation for qualified labor, carts of sand or gravel, bricks for construction, sand, fence, water supply, transportation costs, donations of materials etc. Additionally, community leaders can sign a statement of interest. Community leaders include local municipal leaders, religious leaders, civil society leaders, or any governing body that has oversight over where the project will be implemented. One community leader can sign the statement of interest; however, multiple signatures are strongly encouraged. Community leaders may also submit letters of support for the project. Elements of a Successful Project The project is initiated by the community. The project plan contains pre-established long-term goals and a coherent plan to keep the project running in the future. A capable project manager who is a long-term resident in the community is responsible for the project. There is strong coordination and communication among the grant recipient, local leaders, and local government representatives. The project makes use of materials and supplies that can be maintained by the community, and the materials that will not harm the environment. The project has a high beneficiary to budget ratio, benefiting a significant number of community members The project budget is clear, complete, and well defined. The project responds to a community need and is based on a well-developed proposal that is responsive to the priorities and criteria explained in this NOFO. Project activities and results show long-term sustainability. Application Documents and Procedures 1. Applications for Special Self-Help Funds should include the following: a. Completed SSH form, which can be downloaded here. b. Detailed building plan with dimensions (if necessary/ if small-scale construction envisioned in the project proposal). c. Project location (include map if available). d. Any additional information/literature you have about your organization and/or project. 2. The following documents are required: Mandatory application forms SF-424 (Application for Federal Assistance organizations) SF-424A (Budget Information for Non-Construction programs) The forms can be downloaded from grants.gov. Instructions are available on the Embassy website at the grant support resources toolkit 3. Make sure that the below is addressed in your SSH form, or submit the following: Summary Page: Cover sheet stating the applicant s name and organization, proposal date, program title, program period proposed start and end date, and brief purpose of the program. Proposal (3 pages maximum): The proposal should contain sufficient information that anyone not familiar with it would understand exactly what the applicant wants to do. You may use your own proposal format, but it must include. Proposal Summary: Short narrative that outlines the proposed program, including program objectives and anticipated impact. Introduction to the Organization or Individual applying: A description of past and present operations, showing ability to carry out the program, including information on all previous grants from the U.S. Embassy and/or U.S. government agencies. Problem Statement: Clear, concise and well-supported statement of the problem to be addressed and why the proposed program is needed. Program Goals and Objectives: The goals describe what the program is intended to achieve. The objectives refer to the intermediate accomplishments on the way to the goals. These should be achievable and measurable. Program Activities: Describe the program activities and how they will help achieve the objectives. Program Methods and Design: A description of how the program is expected to work to solve the stated problem and achieve the goal. Include a logic model as appropriate. Proposed Program Schedule and Timeline: The proposed timeline for the program activities. Include the dates, times, and locations of planned activities and events. Key Personnel: Names, titles, roles and experience/qualifications of key personnel involved in the program. What proportion of their time will be used in support of this program? Program Partners: List the names and type of involvement of key partner organizations and sub-awardees. Program Monitoring and Evaluation Plan: This is an important part of successful grants. Throughout the time-frame of the grant, how will the activities be monitored to ensure they are happening in a timely manner, and how will the program be evaluated to make sure it is meeting the goals of the grant? Future Funding or Sustainability Applicant s plan for continuing the program beyond the grant period, or the availability of other resources, if applicable. 4. Budget Justification Narrative: After filling out the SF-424A Budget (above), use a separate sheet of paper to describe each of the budget expenses in detail. Proposals can be submitted in English or Portuguese languages. Submit the complete application package to the U.S. Self-Help Coordinator/ Praia Grants. Applications will be accepted in electronic format, on a rolling basis. Email all required information to praiagrants@state.gov Application Deadline: Applications received after June will be considered with the next application period or will not be considered. Project selections will be announced by October. Applications will be evaluated on the following factors: Completeness: Did the applicant submit all of the materials requested, including but not limited to requirements in the SSH forms found on U.S. Embassy Praia s website. Embassy priorities: Does the application describe how the project s goals are related to the Embassy priorities stated in this document? Sustainability: Is the project sustainable in the long term? Will the project be able to continue without additional investment? Are the suggested measurements of success adequate? Need: Does the project adequately fulfill a stated need within a community? Budget: Is the budget complete, and well defined? Is the budget reasonable? Completion within one year: Can the project be completed in a single year? Community support: Does the project show strong community support? Impact: Does the project benefit the broadest numbers of beneficiaries possible? Is there a substantial impact on the affected community? Contribution and Group Capabilities: Does the group provide adequate resources and show commitment to the project? Is the group capable of administering the project as designed? Review and Selection Process: A review committee will evaluate all eligible applications. Other Required Documentation/ Reporting: Groups selected for funding will subsequently need to submit several required forms, including U.S. Standard Form 424, a grants award document, and any other terms and conditions required by U.S. Embassy Praia. Performance and financial reports will be required throughout the duration of the award. Publicity Campaign: It is expected that publicity will be given to the Ambassador s Special Self-Help program and its projects, including press and radio releases, photographs, and project site plaques that acknowledge the shared efforts of Cabo Verde and the United States. Publicity costs should be considered in the proposed budget. Funding: U.S. Embassy Praia is not required to fund any applications. Submitting an application does not guarantee selection.

$3K – $10K
rolling
other

Free to search & build · $99 one-time to unlock the application pack · No subscription

Understanding and Treating Ataxia-Telangiectasia (R01)

open

National Institutes of Health

Purpose. The National Institute of Neurological Disorders and Stroke (NINDS), National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHBLI), National Human Genome Research Institute (NHGRI), National Institute on Aging (NIA), National Institute of Child Health and Human Development (NICHD), National Institute on Deafness and Other Communication Disorders (NIDCD), National Institute of Environmental Health Sciences (NIEHS), in conjunction with the Ataxia-Telangiectasia Children s Project (A-TCP) and the A-T Ease Foundation, invite research grant applications aimed at understanding or treating Ataxia-Telangiectasia (A-T). The aim of this FOA is to encourage basic, translational and clinical studies to determine how the symptoms of A-T develop, to stimulate the development of resources to further A-T research, to accelerate research into promising therapeutic approaches for A-T and to stimulate progress in A-T research through encouraging and facilitating interdisciplinary interactions. Mechanism of Support. This funding opportunity will utilize the NIH R01 mechanism, and runs in parallel with two other FOAs of identical scientific scope (R21, PA-07-273 and R03, PA-07-274) that solicit applications under the NIH Exploratory/Developmental grant mechanism (R21), and the NIH Small Research Grant (R03) mechanism, respectively. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations.

rolling
Education

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Understanding and Treating Ataxia-Telangiectasia (R03)

open

National Institutes of Health

Purpose. The National Institute of Neurological Disorders and Stroke (NINDS), National Cancer Institute (NCI), National Human Genome Research Institute (NHGRI), National Institute on Aging (NIA), National Institute of Child Health and Human Development (NICHD), and the National Institute of Environmental Health Sciences (NIEHS), in conjunction with the Ataxia-Telangiectasia Children s Project (A-TCP) and the A-T Ease Foundation, invite research grant applications aimed at understanding or treating Ataxia-Telangiectasia (A-T). The aim of this FOA is to encourage basic, translational and clinical studies to determine how the symptoms of A-T develop, to stimulate the development of resources to further A-T research, to accelerate research into promising therapeutic approaches for A-T and to stimulate progress in A-T research through encouraging and facilitating interdisciplinary interactions. Mechanism of Support. This FOA will utilize the NIH Small Research Grant (R03) award mechanism and runs in parallel with two other FOAs of identical scientific scope (R01, PA-07-272 and R21, PA-07-273) that solicit applications under the NIH Traditional Research Project Grant (R01) mechanism, and the NIH Exploratory/Developmental Grant (R21) mechanism, respectively. The R03 grant mechanism supports different types of projects including pilot and feasibility studies; secondary analysis of existing data; small, self-contained research projects; development of research methodology; and development of new research technology. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources. The R03 is not renewable. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Budget and Project Period: Budgets for direct costs of up to $50,000 per year and a project duration of up to two years may be requested for a maximum of $100,000 direct costs over a two-year project period. Eligible Organizations: Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations.

Up to $50K
rolling
Education

Free to search & build · $99 one-time to unlock the application pack · No subscription

Understanding and Treating Ataxia-Telangiectasia (R21)

open

National Institutes of Health

Purpose. The National Institute of Neurological Disorders and Stroke (NINDS), National Cancer Institute (NCI), National Heart, Lung, and Blood Institute (NHBLI), National Human Genome Research Institute (NHGRI), National Institute on Aging (NIA), National Institute of Child Health and Human Development (NICHD), National Institute on Deafness and Other Communication Disorders (NIDCD), and the National Institute of Environmental Health Sciences (NIEHS), in conjunction with the Ataxia-Telangiectasia Children s Project (A-TCP) and the A-T Ease Foundation, invite research grant applications aimed at understanding or treating Ataxia-Telangiectasia (A-T). The aim of this FOA is to encourage basic, translational and clinical studies to determine how the symptoms of A-T develop, to stimulate the development of resources to further A-T research, to accelerate research into promising therapeutic approaches for A-T and to stimulate progress in A-T research through encouraging and facilitating interdisciplinary interactions. Mechanism of Support. This FOA will utilize the NIH Exploratory/Developmental (R21) award mechanism and runs in parallel with two other FOAs of identical scientific scope (R01, PA-07-272 and R03, PA-07-274) that solicit applications under the NIH Traditional Research Project Grant (R01) mechanism, and the NIH Small Research Grant (R03) mechanism, respectively. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Budget and Project Period. The total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year. The R21 is not renewable. Eligible Organizations: Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations.

Up to $200K
rolling
Education

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UNITED STATES MILITARY ACADEMY Broad Agency Announcement

open

Dept of the Army -- Materiel Command

The U.S. Military Academy at West Point's mission is "to educate, train, and inspire the Corps of Cadets so that each graduate is a commissioned leader of character committed to the values of Duty, Honor, Country and prepared for a career of professional excellence and service to the Nation as an officer in the United States Army." The United States Military Academy is located at West Point, New York. USMA executes research to enhance the education of cadets, develop the faculty professionally, and address important issues facing the Army and the Nation. In addition, the Academy conducts research and analysis in emerging fields that may realize novel or vastly improved Army capabilities. At West Point, research is organized and administered through centers and institutes, most of which reside within academic departments. These centers and institutes, affiliated with each other through the Academy Research Council (ARC), coordinated and supported by the Academic Research Division (ARD), provide the infrastructure necessary to tackle the nation s and the world s most challenging problems. Our research centers and institutes bring context to the classroom, are central to our vibrant and pioneering faculty, and are one way West Point connects to the Army and to the Nation. Our students are driven, our faculty is world-class, and through our centers, scholars and scientists thrive and produce their best work. Cadets regularly win Best Paper Awards at national and international graduate-level conferences, our faculty hold fellowships and chairmanships in their discipline's national organizations and our products are deployed to the soldier. In addition to applied research, there are centers and institutes at West Point that focus on other aspects of the USMA mission.The USMA BAA identifies topics of interest to the USMA departments, directorates, and research centers and institutes. These groups focus on executing in-house research programs, with a significant emphasis on collaborative research with other organizations. The groups fund a modest amount of extramural research in certain specific areas, and those areas are described in this BAA.The USMA BAA seeks proposals from institutions of higher education, nonprofit organizations, state and local governments, foreign organizations, foreign public entities, and for-profit organizations (i.e., large and small businesses) for research based on the following campaigns: Socio-Cultural; Information Technology; Ballistics, Weapons, and Protections; Energy and Sustainability; Materials, Measurements, and Facilities; Unmanned Systems and Space; Human Support Systems; and Artificial Intelligence, Machine Learning, and Quantum Technologies.Proposals are sought for cutting-edge innovative research that could produce discoveries with a significant impact to enable new and improved Army technologies and related operational capabilities and related technologies. The specific research areas and topics of interest described in this document should be viewed as suggestive, rather than limiting.

2027-03-31
sciencetechnology

Free to search & build · $99 one-time to unlock the application pack · No subscription

Village of Mount Morris

open

Mount Morris

Small Business

Up to $69K
Rolling
general

Free to search & build · $99 one-time to unlock the application pack · No subscription

Village of St. Johnsville

open

St. Johnsville

Small Business

Up to $90K
Rolling
general

Free to search & build · $99 one-time to unlock the application pack · No subscription

Vulvodynia - Systematic Epidemiologic, Etiologic Or Therapeutic Studies (R01)

open

National Institutes of Health

Purpose. This Funding Opportunity Announcement (FOA)issued by the National Institute of Child Health and Human Development (NICHD) and the Office of Research on Women s Health (ORWH), National Institutes of Health (NIH), solicits investigator-initiated applications that address basic, clinical, translational, epidemiological and/or behavioral research that concentrates on studies of relevance to vulvodynia and that advance prevention and therapeutic opportunities Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations .

rolling
Healthhealthcare

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