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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

National Institutes of Health

open
OpenLast verified: 2026-06-18

About This Grant

The NIH Exploratory/Developmental Grant supports exploratory and developmental research projects by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research. This Parent Notice of Funding Opportunity requires that at least 1 clinical trial be proposed. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.Applicants should note that some ICs (see Related Notices) only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.

Grant Summary

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) is a National Institutes of Health grant providing funding that varies by award for nonprofit, municipality, school district. Applications are due 2028-01-07 (open). Check eligibility and apply with FindGrants.

Focus Areas

healthincome_security_and_social_servicesenvironmenteducation

Eligibility

  • Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
nonprofitmunicipalityschool districtuniversitysmall businesstribal government

How to Apply

Funding Range

Up to $0K

Deadline

2028-01-07

Complexity
Medium
  1. 1Confirm your organization is eligible for NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) from National Institutes of Health, checking organization type, location, and any population or project requirements.
  2. 2Gather the required documents and information, including your organization details, project plan, and budget figures.
  3. 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
  4. 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required): Frequently Asked Questions

Who is eligible for the NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)?

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) is offered by National Institutes of Health and is generally open to nonprofit, municipality, school district, university, small business, tribal government. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.

How much funding does the NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) provide?

NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.

When is the NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) deadline?

Applications for NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required) are due 2028-01-07 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.

How do you apply for the NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)?

To apply for NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.

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