Search Grants — Free, No Account Required

New York Empire State Development (ESD)

New York Empire State Development (ESD) offers grants, incentives, and financial assistance for small businesses, startups, and economic development projects in NY.

Government of Newfoundland and Labrador

Supports small business development, innovation, and export growth in Newfoundland and Labrador.

National Institutes of Health

This Funding Opportunity Announcement (FOA) solicits Small Business Innovation Research (SBIR) grant applications from small business concerns (SBCs) that propose the advanced stage development of pharmacological treatment agents for drug and nicotine abuse and dependence. This FOA specifically invites applications for the competing renewal (formerly competing continuation ) of previously funded Phase II SBIR grants, to take existing, promising compounds through the next step of drug discovery and development.

National Institutes of Health

The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization. The Phase IIB Strategic Breakthrough provides previously funded NIH SBIR or STTR projects additional support for later-stage research and development (R&D).

National Institutes of Health

NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

National Institutes of Health

The NIH Phase IIB Strategic Breakthrough award bridges the funding gap between the end of a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase II award and commercialization. The Phase IIB Strategic Breakthrough provides previously funded NIH SBIR or STTR projects additional support for later-stage research and development (R&D).

National Institutes of Health

The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.

National Institutes of Health

The Small Business Technology Transfer (STTR) grant program helps United States small business concerns (SBCs) that partner with a nonprofit research institution bring scientific innovations to the marketplace. The STTR program supports feasibility studies to later stage research and development (R&D) needed to develop a commercial product.

National Institutes of Health

NIH Small Business Technology Transfer Grant (Parent STTR [R41/R42] Clinical Trial Optional)

National Institutes of Health

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

National Institutes of Health

The Small Business Innovation Research (SBIR) program helps United States small business concerns (SBCs) bring scientific innovations to the marketplace. The SBIR program supports feasibility studies to later research and development (R&D) needed to develop a commercial product.

National Institutes of Health

NIH, CDC and FDA Small Business Innovation Research Grant (Parent SBIR [R43/R44] Clinical Trial Optional)

National Institute of Standards and Technology

Supports a network of centers providing technical assistance, workforce development, and business services to small and mid-sized manufacturers.

New Jersey Economic Development Authority

Comprehensive suite of programs including Emerge tax credits, angel investor tax credits, small business grants, and innovation vouchers.

North Carolina Department of Commerce

North Carolina Department of Commerce offers grants, incentives, and financial assistance for small businesses, startups, and economic development projects in NC.

DEPT OF DEFENSE.DEPT OF THE ARMY.US ARMY CORPS OF ENGINEERS.ENGINEER DIVISION SOUTH ATLANTIC.ENDIST MOBILE.W074 ENDIST MOBILE

North Region Small Business MATOC (Northern Alabama, Tennessee and Mississippi)

Golden Field Office

The purpose of this Notice of Intent is to provide potential applicants advance notice that the Office of Energy Efficiency and Renewable Energy (EERE) intends to issue, on behalf of the Technology-to-Market Team in the Office of Strategic Programs, a Funding Opportunity Announcement (FOA) entitled ?Cleantech University Prize (Cleantech UP)?, Number DE-FOA-0001271. The full Notice of Intent DE-FOA-0001284 is posted on the EERE eXCHANGE website at https://eere-exchange.energy.gov. The Cleantech UP program seeks to catalyze clean energy start-up formation on college campuses, support novel training and educational opportunities that equip the next generation of energy entrepreneurs and innovators across the country, establish a national-level training program and competition for America?s top clean energy student entrepreneurs, and create a sustained and diverse community to support student entrepreneurs. The mission of EERE?s Technology-to-Market Team is to aid EERE technology offices and American energy innovation stakeholders in addressing the technological and financial barriers to bring new intellectual property to market. To advance this mission, the Technology-to-Market Sub-Program supports a variety of commercialization and entrepreneurship activities in partnership with U.S. Department of Energy (DOE) national laboratories, universities, businesses, and nonprofit organizations around the country. Existing activities include the DOE National Clean Energy Business Plan Competition (DOE NCEBPC), National Incubator Initiative for Clean Energy, Lab-Corps, and Small Business Innovation Research/Small Business Technology Transfer Programs (SBIR/STTR); past activities include the Innovation Ecosystem Development Initiative, i6 Green Challenge, Technology Commercialization Fund, Entrepreneurs-in-Residence, and other initiatives. NO APPLICATIONS WILL BE ACCEPTED THROUGH THIS NOTICE. Please do not submit questions or respond to this Notice of Intent. Prospective applicants to the FOA should begin developing partnerships, formulating ideas, and gathering data in anticipation of the issuance of this FOA. DOE plans to issue the FOA around mid-February 2015. The applicant must first register and create an account on the EERE eXCHANGE website. A User Guide for EERE eXCHANGE can be found on the EERE website https://eere-exchange.energy.gov/Manuals.aspx after logging in to the system.

Golden Field Office

The Office of Energy Efficiency and Renewable Energy (EERE) intends to issue, on behalf of the Advanced Manufacturing Office (AMO), a Funding Opportunity Announcement (FOA) entitled Industrial Assessment Centers (DE-FOA-0001513). This FOA supports EERE AMO technical assistance activities. The goal of the Industrial Assessment Center (IAC) program is twofold: first, to assist small and medium-sized enterprises (SMEs), currently defined as having gross annual sales below $100 million, fewer than 500 employees, and annual energy bills between $100,000 and $2.5 million, to increase their energy efficiency, productivity, sustainability and competitiveness; and second, to help address a growing shortage of engineering professionals with applied energy-related skills. Prospective IACs can demonstrate their capabilities and describe their approach to serve small and medium-sized manufacturers by analyzing the operating characteristics, productivity, and energy, water and waste usage of manufacturing facilities; identifying, quantifying, and recommending specific opportunities to improve energy and water efficiency, reduce waste, and improve productivity; including potential enhancements to cyber security and related information technologies; and reporting the findings to the facility, together with estimates of the energy savings opportunities, implementation costs, and payback periods. Each IAC will provide extensive training for undergraduate and graduate engineering students in industrial processes, energy assessment procedures, and energy management systems. IAC Applicants should define how they will maximize the student experience; increase student technical knowledge and business sense; and develop their understanding of key industrial concepts, including industrial supply chains, sustainability issues, and management systems. This NOI is issued so that interested parties are aware of EERE s intention to issue a FOA in the near term. All of the information contained in this NOI is subject to change. EERE may issue a FOA as described herein, may issue a FOA that is significantly different than the FOA described herein, or DOE may not issue a FOA at all. Please access the complete Notice of Intent on https://eere-exchange.energy.gov/. NO APPLICATIONS WILL BE ACCEPTED THROUGH THIS NOTICE. Please do not submit questions or respond to this NOI. Prospective applicants to the FOA should begin developing partnerships, formulating ideas, and gathering data in anticipation of the issuance of this FOA. It is anticipated that this FOA will be posted to EERE Exchange in March 2016. The applicant must first register and create an account on the EERE Exchange website. A User Guide for the EERE Exchange can be found on the EERE website http://eere.energy.gov/financing/exchangeExchange/Manuals.aspx after logging in to the system.

National Institutes of Health

The purpose of this funding opportunity announcement (FOA) is to encourage the submission of applications for research to enhance animal stem cells as model biological systems. Innovative approaches to isolate, characterize and identify toti-potent and multi-potent stem cells from nonhuman biomedical research animal models, as well as to generate reagents and techniques to characterize and separate those stem cells from other cell types is encouraged. Studies involving human subjects are not allowed under this FOA. Because the nature and scope of the proposed research may vary from application to application, it is anticipated that the size and duration of each award may also vary. The total amount awarded and the number of awards will depend upon the numbers, quality, duration, and costs of the applications received. Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism and runs in parallel with a FOA of identical scientific scope, PA-07-303, that solicits applications under the R01 grant mechanism. Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications. Budget and Project Period: The total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $275,000 over an R21 two-year period, with no more than $200,000 in direct costs allowed in any single year.The R21 is not renewable. Eligible Organizations: Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Non-domestic (non-U.S.) Entity (Foreign Organization); Small Business; For-Profit Organization (Other than Small Business).

Naval Research Laboratory

<p>Amendment 0006</p><p><br></p><p>The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. </p><p>--------------------------------------------------------------</p><p><br></p><p>Amendment 0005</p><p><br></p><p>The purpose of this amendment is to provide a searchable list of Summary Topics contained in Appendix 1. Expanded descriptions of each topic can be found in the full announcement pdf.</p><p><br></p><p>APPENDIX 1 – RESEARCH DESCRIPTION - SUMMARY TOPICS</p><p><strong>&nbsp;</strong></p><p><strong>II. Detailed information about the funding opportunity</strong></p><p><strong>&nbsp;</strong></p><p>The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The basic research program is driven by perceptions about future requirements of the Navy.</p><p><br></p><p>The Navy's operational effectiveness depends on its ability to keep pace with rapidly developing technologies. NRL contributes to this requirement by conducting research in the following areas, organized into NRL'S three research directorates and Naval Center for Space Technology:</p><p><br></p><p>Systems Directorate Code 5000</p><p>Materials Science and Component Technology Directorate Code 6000 Ocean and Atmospheric Science and Technology Directorate Code 7000 Naval Center for Space Technology Code 8000</p><p><br></p><p>A.&nbsp;&nbsp;&nbsp;SYSTEMS DIRECTORATE - CODE 5000</p><p><u>53-24-01</u> - HIGH FREQUENCY RADAR</p><p><u>53-24-01C</u> - HIGH FREQUENCY RADAR (CLASSIFIED)</p><p><u>53-24-02</u> - LOW-COST WIDEBAND ANTENNA ARRAY TECHNOLOGIES</p><p><u>53-24-03</u> - ADVANCED COMPUTATIONAL ELECTROMAGNETICS</p><p><u>55-24-01</u> - INFORMATION AND DECISION SCIENCES</p><p><u>55-24-02</u> - MATHEMATICAL FOUNDATIONS OF HIGH ASSURANCE COMPUTING</p><p><u>55-24-03</u> - HIGH ASSURANCE ENGINEERING AND COMPUTING</p><p><u>55-24-04</u> - ADVANCED NAVAL NETWORK SOLUTIONS</p><p><u>55-24-05</u> - FEDERATED, DISTRIBUTED COMPUTING/NETWORK INFRASTRUCTURE</p><p><u>56-24-01</u> - OPTICAL SCIENCES R&amp;D</p><p><u>57-24-01</u>&nbsp;- ELECTROMAGNETIC TECHNIQUES AND TECHNOLOGY RESEARCH AND DEVELOPMENT</p><p><u>57-24-02&nbsp;&nbsp;​</u>- SHIPBOARD ELECTRONIC WARFARE</p><p><strong>&nbsp;</strong></p><p><strong>B.&nbsp;MATERIALS SCIENCE AND COMPONENT TECHNOLOGY DIRECTORATE CODE 6000</strong></p><p><u>60-24-01</u> - HIGH PERFORMANCE COMPUTING ON MASSIVELY PARALLEL ARCHITECTURES</p><p><u>61-24-01</u> - ELECTROCHEMICAL ENERGY STORAGE, CONVERSION AND COMMAND/CONTROL</p><p><u>61-24-02 </u>- CORROSION PROCESSES, CONTROL, MITIGATION, AND TECHNOLOGY</p><p><u>61-24-03</u> - APPLICATIONS OF MOLECULAR BIOLOGY, BIOCHEMISTRY, ANALYTICAL CHEMISTRY AND ADVANCED LASER TECHNIQUES</p><p><u>61-24-04</u> - MULTIECHELON DIAGNOSTICS (MEDx) TECHNOLOGY DEVELOPMENT AND TIERED EVALUATION</p><p><u>63-24-01</u> - MATERIALS PERFORMANCE, PROCESSING, AND MODELING</p><p><u>67-24-01</u> - BASIC AND APPLIED RESEARCH IN PLASMA SCIENCE</p><p><u>68-24-01</u> - RADIATION EFFECTS RESEARCH</p><p><u>68-24-02</u> - PHOTOVOLTAICS FOR PORTABLE POWER</p><p><strong>&nbsp;</strong></p><p><strong>C.&nbsp;&nbsp;&nbsp;OCEAN AND ATMOSPHERIC SCIENCE AND TECHNOLOGY DIRECTORATE CODE 7000</strong></p><p><u>71-24-01</u> - ACOUSTIC SIMULATION AND TACTICS</p><p><u>72-24-01</u> - LOW FREQUENCY RADIO INTERFEROMETRY</p><p><u>72-24-02</u> - OPTICAL REMOTE SENSING OF THE COASTAL REGIME</p><p><u>72-24-03</u> - REMOTE SENSORS AND IMAGING SYSTEMS</p><p><u>72-24-04</u> - AIRBORNE, SHIPBOARD, AND OVERHEAD DATA ACQUISITION AND ANALYSIS</p><p><u>73-24-01</u> - OCEAN DYNAMICS AND PREDICTION OCEANOGRAPHY</p><p><u>73-24-02</u> - SEAFLOOR SCIENCES</p><p><u>73-24-03</u> - GEOSPATIAL SCIENCES AND TECHNOLOGY</p><p><u>75-24-01</u> - ATMOSPHERIC EFFECTS, ANALYSIS, AND PREDICTION</p><p><u>76-24-01</u> - RESEARCH INTO SPACE, BACKGROUNDS, IMAGING AND MODELING</p><p><strong>&nbsp;</strong></p><p><strong>D.&nbsp;&nbsp;&nbsp;NAVAL CENTER FOR SPACE TECHNOLOGY CODE 8000</strong></p><p><u>82-24-01</u> - SPACECRAFT &amp; SPACE SYSTEMS TECHNOLOGY</p><p><br></p><p>--------------------------------------------------------------</p><p>Amendment 0004</p><p><br></p><p>The purpose of this amendment is to extend the due date for acceptance of White Papers and revise Appendix 1 Summary Topics and email addresses in it’s entirety.</p><p>--------------------------------------------------------------</p><p>Amendment 0003</p><p><br></p><p>The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged.</p><p><br></p><p>-------------------------------------------------------------</p><p>Amendment 0002</p><p><br></p><p>The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged.</p><p><br></p><p>-------------------------------------------------------------</p><p>Amendment 0001</p><p><br></p><p>The purpose of this amendment is to extend the due date for acceptance of White Papers.&nbsp;All other terms and conditions remain unchanged.</p><p><br></p><p>--------------------------------------------------------------</p><p>The Naval Research Laboratory is interested in receiving innovative proposals that offer potential for advancement and improvement in the technical topic areas listed. This notice constitutes a Broad Agency Announcement (BAA) as contemplated in FAR 6.302(d) that provides for the competitive selection of research proposals. The Government reserves the right to select for award all, some, or none of the proposals received. Awards under this BAA are expected to take the form of Contracts, Grants, Cooperative Agreements and Other Transactions may also be awarded if appropriate. NRL encourages Educational Institutions, Small Businesses (SBs), Small Disadvantaged Business Concerns (SDBs) and Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) to submit proposals under this BAA.</p><p>In order to conserve valuable offeror and Government resources, prospective offerors shall first submit a White Paper (WP) to the email address identified in the individual Summary Topics contained in Appendix 1, to include a rough cost estimate. If there is interest in the proposed research the offeror will be invited to submit a Formal Proposal.&nbsp;The selection of proposals for award will be based on a scientific review of proposals submitted in response to each BAA Summary Topic. The major purpose of the evaluation will be to determine the relative merit of the technical approach of each proposal. Business and contractual aspects, including proposed&nbsp;cost and cost realism, will also be considered as part of the evaluation. Selection of proposals for award will be based on the potential benefits to the Government weighed against the cost of the proposals, in view of the availability of funds. The complete BAA including proposal preparation instructions, award considerations, and evaluation criteria is also available at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/ .</p><p><br></p>

Naval Research Laboratory

Amendment 0006The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged. --------------------------------------------------------------Amendment 0005The purpose of this amendment is to provide a searchable list of Summary Topics contained in Appendix 1. Expanded descriptions of each topic can be found in the full announcement pdf.APPENDIX 1 RESEARCH DESCRIPTION - SUMMARY TOPICS II. Detailed information about the funding opportunity The Naval Research Laboratory (NRL) is the Navy's corporate laboratory. NRL conducts basic and applied research for the Navy in a variety of scientific and technical disciplines. The basic research program is driven by perceptions about future requirements of the Navy.The Navy's operational effectiveness depends on its ability to keep pace with rapidly developing technologies. NRL contributes to this requirement by conducting research in the following areas, organized into NRL'S three research directorates and Naval Center for Space Technology:Systems Directorate Code 5000Materials Science and Component Technology Directorate Code 6000 Ocean and Atmospheric Science and Technology Directorate Code 7000 Naval Center for Space Technology Code 8000A. SYSTEMS DIRECTORATE - CODE 500053-24-01 - HIGH FREQUENCY RADAR53-24-01C - HIGH FREQUENCY RADAR (CLASSIFIED)53-24-02 - LOW-COST WIDEBAND ANTENNA ARRAY TECHNOLOGIES53-24-03 - ADVANCED COMPUTATIONAL ELECTROMAGNETICS55-24-01 - INFORMATION AND DECISION SCIENCES55-24-02 - MATHEMATICAL FOUNDATIONS OF HIGH ASSURANCE COMPUTING55-24-03 - HIGH ASSURANCE ENGINEERING AND COMPUTING55-24-04 - ADVANCED NAVAL NETWORK SOLUTIONS55-24-05 - FEDERATED, DISTRIBUTED COMPUTING/NETWORK INFRASTRUCTURE56-24-01 - OPTICAL SCIENCES R&amp;D57-24-01 - ELECTROMAGNETIC TECHNIQUES AND TECHNOLOGY RESEARCH AND DEVELOPMENT57-24-02 - SHIPBOARD ELECTRONIC WARFARE B. MATERIALS SCIENCE AND COMPONENT TECHNOLOGY DIRECTORATE CODE 600060-24-01 - HIGH PERFORMANCE COMPUTING ON MASSIVELY PARALLEL ARCHITECTURES61-24-01 - ELECTROCHEMICAL ENERGY STORAGE, CONVERSION AND COMMAND/CONTROL61-24-02 - CORROSION PROCESSES, CONTROL, MITIGATION, AND TECHNOLOGY61-24-03 - APPLICATIONS OF MOLECULAR BIOLOGY, BIOCHEMISTRY, ANALYTICAL CHEMISTRY AND ADVANCED LASER TECHNIQUES61-24-04 - MULTIECHELON DIAGNOSTICS (MEDx) TECHNOLOGY DEVELOPMENT AND TIERED EVALUATION63-24-01 - MATERIALS PERFORMANCE, PROCESSING, AND MODELING67-24-01 - BASIC AND APPLIED RESEARCH IN PLASMA SCIENCE68-24-01 - RADIATION EFFECTS RESEARCH68-24-02 - PHOTOVOLTAICS FOR PORTABLE POWER C. OCEAN AND ATMOSPHERIC SCIENCE AND TECHNOLOGY DIRECTORATE CODE 700071-24-01 - ACOUSTIC SIMULATION AND TACTICS72-24-01 - LOW FREQUENCY RADIO INTERFEROMETRY72-24-02 - OPTICAL REMOTE SENSING OF THE COASTAL REGIME72-24-03 - REMOTE SENSORS AND IMAGING SYSTEMS72-24-04 - AIRBORNE, SHIPBOARD, AND OVERHEAD DATA ACQUISITION AND ANALYSIS73-24-01 - OCEAN DYNAMICS AND PREDICTION OCEANOGRAPHY73-24-02 - SEAFLOOR SCIENCES73-24-03 - GEOSPATIAL SCIENCES AND TECHNOLOGY75-24-01 - ATMOSPHERIC EFFECTS, ANALYSIS, AND PREDICTION76-24-01 - RESEARCH INTO SPACE, BACKGROUNDS, IMAGING AND MODELING D. NAVAL CENTER FOR SPACE TECHNOLOGY CODE 800082-24-01 - SPACECRAFT &amp; SPACE SYSTEMS TECHNOLOGY--------------------------------------------------------------Amendment 0004The purpose of this amendment is to extend the due date for acceptance of White Papers and revise Appendix 1 Summary Topics and email addresses in it s entirety.--------------------------------------------------------------Amendment 0003The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged.-------------------------------------------------------------Amendment 0002The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged.-------------------------------------------------------------Amendment 0001The purpose of this amendment is to extend the due date for acceptance of White Papers. All other terms and conditions remain unchanged.--------------------------------------------------------------The Naval Research Laboratory is interested in receiving innovative proposals that offer potential for advancement and improvement in the technical topic areas listed. This notice constitutes a Broad Agency Announcement (BAA) as contemplated in FAR 6.302(d) that provides for the competitive selection of research proposals. The Government reserves the right to select for award all, some, or none of the proposals received. Awards under this BAA are expected to take the form of Contracts, Grants, Cooperative Agreements and Other Transactions may also be awarded if appropriate. NRL encourages Educational Institutions, Small Businesses (SBs), Small Disadvantaged Business Concerns (SDBs) and Historically Black Colleges and Universities (HBCUs) and Minority Institutions (MIs) to submit proposals under this BAA.In order to conserve valuable offeror and Government resources, prospective offerors shall first submit a White Paper (WP) to the email address identified in the individual Summary Topics contained in Appendix 1, to include a rough cost estimate. If there is interest in the proposed research the offeror will be invited to submit a Formal Proposal. The selection of proposals for award will be based on a scientific review of proposals submitted in response to each BAA Summary Topic. The major purpose of the evaluation will be to determine the relative merit of the technical approach of each proposal. Business and contractual aspects, including proposed cost and cost realism, will also be considered as part of the evaluation. Selection of proposals for award will be based on the potential benefits to the Government weighed against the cost of the proposals, in view of the availability of funds. The complete BAA including proposal preparation instructions, award considerations, and evaluation criteria is also available at https://www.nrl.navy.mil/Doing-Business/Contracts/Broad-Agency-Announcements/ .

NYC Department of Small Business Services

Grants for neighborhood commercial revitalization, storefront improvement, and community development in New York City.

Ohio Development Services Agency

Ohio Development Services Agency offers grants, incentives, and financial assistance for small businesses, startups, and economic development projects in OH.

National Institutes of Health

Purpose. This FOA encourages examination of differences in genomics, proteomics, and metabolomics and other omics that may be responsible for variations in individual responses to complementary and alternative medicine (CAM) (NCCAM) or bioactive food component (NCI) interventions using samples obtained from ongoing and completed clinical studies. Mechanism of Support. This Funding Opportunity Announcement (FOA) will utilize the R01 grant mechanism and runs in parallel with a FOA of identical scientific scope, PAR-07-378, that solicits applications under the R21 mechanism. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations. Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct Renewals and Resubmissions. At this time, it is not known if competing renewal (formerly competing continuation ) applications will be accepted and/or if this FOA will be reissued. Applicants may submit a resubmission application, but such application must include an Introduction addressing the previous peer review critique (Summary Statement). Number of PDs/PIs. More than one PD/PI, or multiple PDs/PIs, may be designated on the application.