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NIBIB - National Institute of Biomedical Imaging and Bioengineering

Abstract Laboratory automation is reshaping scientific discovery by enabling high-throughput, precise, and scalable experimentation. Yet, unlike fields such as manufacturing, transportation, and agriculture—where robotics has driven rapid advances in innovation—laboratory automation has lagged behind. Most commercial lab robots are still built to mimic human pipetting rather than enabling experiments that were previously impossible to execute manually. Closed, proprietary platforms prevent researchers from fully leveraging their computational skills and severely limit training opportunities for students and early-stage investigators. This project addresses those gaps by expanding PyLabRobot (PLR), a free, open-source, Python-based framework for designing, simulating, and executing complex liquid handling protocols across a wide range of robotic systems. PLR is software- and hardware-agnostic, supports complete virtual simulation, and can be run in the cloud, making it accessible to anyone with basic Python skills—no expensive equipment required. By enabling users to develop and debug protocols entirely in simulation, PLR allows students, educators, and researchers to build automation expertise before ever stepping into a physical lab. This significantly lowers the entry barrier and ensures that trainees enter the workforce ready to contribute immediately to automation-driven projects. Python’s ubiquity across STEM and engineering makes PLR a natural training tool for modern science. In a recent graduate-level class piloting PLR in full simulation mode, students with no prior robotics background programmed highly sophisticated workflows running from CRISPRi screening, AlphaLISA and TR-FRET assays, small molecule synthesis, FISH staining, and cell line manufacturing—demonstrating both the accessibility and real-world relevance of the platform. These examples highlight PLR’s potential not just to replicate existing workflows, but to unlock new experimental designs that would be infeasible with manual techniques. This R03 proposal supports three focused aims: (1) Create a web-based repository of validated, sharable protocols and documentation to enable reproducibility, benchmarking, and AI-driven method development; (2) Integrate PLR into cloud platforms like Google Colab and develop a dedicated IDE for real-time visualization, debugging, and seamless protocol execution; (3) Build a digital twin simulation engine that models labware, deck layouts, and liquid handling to support predictive optimization before execution. This project is supported by letters of support from the entire PyLabRobot development team and multiple industry stakeholders, including leading automation companies. By removing the barriers that have long constrained laboratory robotics programming, this work will accelerate discovery, lower costs, and build a highly skilled U.S. workforce ready to lead in bioengineering, automation, and advanced manufacturing.

U.S. National Science Foundation

This solicitation is jointly sponsored by the U.S. Environmental Protection Agency (EPA) and the U.S. National Science Foundation (NSF) Division of Chemistry (CHE) to encourage synergy and enhance cooperation in examining the life cycles of synthetic chemicals and materials as they relate to their manufacture, use, transport, and disposal or recycle. The Networks for Characterizing Chemical Life Cycle (NCCLCs) will promote development of trans-disciplinary, systems- and molecular-level understanding of the life cycle of important (relevant) synthetic chemicals and materials (including nanomaterials) as these distribute and are potentially altered through use in society and interaction with the built and natural environments. For this solicitation, "chemicals" refers broadly to any and all materials, compounds, and individual chemicals or mixtures of chemicals, including nanomaterials. Advances resulting from these Networks are expected to provide methods and tools for characterizing and predicting environmental and health implications of chemical manufacture and use across the life cycle. Education, workforce development, and the translation or transfer of basic research results into social or economic benefits are critical aspects of NCCLC projects. Networks will develop strong mentoring and training activities (which include broadening participation elements) for undergraduate and graduate students as well as postdoctoral associates. Other educational activities, such as informal science communication and the education of K-12 students or the public, are encouraged. Where appropriate, intellectual property protection and a proactive plan to engage industry in technology transfer is encouraged. It is expected that research teams in the NCCLC awarded under this solicitation will coordinate / communicate with the funded research networks from the EPA/NSF Networks for Sustainable Molecular Design and Synthesis (NSMDS) solicitation (see: http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=504822). The researchers working in these two network groups are expected to conduct complementary research and; thus, will benefit from interaction with each other at annual EPA All-Investigators Meetings (also known as progress reviews).

U.S. National Science Foundation

This solicitation is jointly sponsored between the U.S. Environmental Protection Agency (EPA) and the National Science Foundation (NSF) Divisions of Chemistry and Chemical, Bioengineering, Environmental, and Transport Systems (CBET) to encourage synergistic research activities and to enhance cooperation among the chemical sciences, materials research, geosciences, engineering, and biomedical and public health communities.?? The agencies jointly issue the solicitation, but will separately fund awards for??Networks for Sustainable Molecular Design and Synthesis (NSMDS). Networks for Sustainable Molecular Design and Synthesis are groups of two or more researchers working in trans-disciplinary fields to promote the development of safe and sustainable chemicals as well as safe and sustainable synthetic procedures. For this solicitation, "chemicals" refers broadly to any and all materials, inorganic and organic compounds,??and??individual chemicals or mixtures of chemicals (e.g., endocrine disruptors, chlorofluorocarbons,??transition metal-based catalysts, macromolecules, and nanomaterials).?? Advances resulting from these Networks are expected to result in chemicals that are safer and more sustainable throughout their life cycle and thus,??the replacement of rare, toxic, and expensive chemicals with earth abundant, benign, and renewable alternatives is anticipated.?? The Networks will facilitate safe design strategies, processes, and pathways (including catalytic pathways) that consume less fresh water, generate less waste, and use less energy than current practice.?? These new approaches will minimize hazards that arise not only from chemical structure and intended use, but also from??their synthesis, production, consumption, reuse, and disposal.Education, workforce development, and the translation or transfer of basic research results??into social or economic benefits??are critical aspects of NSMDS projects.?? Networks will??develop strong mentoring and training activities (which include broadening participation elements) for undergraduate and graduate students as well as postdoctoral associates.?? Other educational activities, such as informal science communication and the education of K-12 students or??the public, are encouraged.?? Where appropriate, intellectual property protection and a proactive plan to engage industry in technology transfer is encouraged. It is expected that research teams in the??NSMDS awarded under this solicitation will coordinate / communicate with the funded research networks from the EPA/NSF Networks for??Characterizing Chemical Life Cycle (NCCLC)??solicitation (see:http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=504811). The researchers working in these two network groups are expected to conduct complementary research and; thus, will benefit from interaction with each other at annual EPA All-Investigators Meetings (also known as progress reviews). ????

U.S. National Science Foundation

The Experimental Program to Stimulate Competitive Research (EPSCoR) is a program designed to fulfill the National Science Foundation's (NSF) mandate to promote scientific progress nationwide. The EPSCoR program is directed at jurisdictions that have historically received lesser amounts of NSF Research and Development (R&D) funding. Thirty-one jurisdictions including twenty-eight states, the Commonwealth of Puerto Rico, the U. S. Virgin Islands, and Guam currently are eligible to participate. Through this program, NSF establishes partnerships with government, higher education, and industry that are designed to effect lasting improvements in a state's or region's research infrastructure, R&D capacity and hence, its national R&D competitiveness.Research Infrastructure Improvement Program: Track-2 (RII Track-2) awards provide funds in the range of $1.5 to 2.0 million per year for up to 3 years to consortia of EPSCoR jurisdictions. The awards promote opportunities for collaborations among EPSCoR jurisdictions in all areas of science, engineering, and education supported by the National Science Foundation (NSF). RII Track-2 proposals must describe a clear, comprehensive, and integrated vision to drive discovery, and train a skilled workforce capable of solving science and engineering challenges of regional, thematic, and national relevance. Proposals should also include a strong rationale for the establishment of the consortium and clearly demonstrate that the consortium is well-positioned to produce results that cannot be obtained by any single partner working independently. The Science, Technology, Engineering, and Mathematics (STEM) research and education activities should broaden participation by different types of institutions, individuals, and sectors in the project.

River Barrel Brewing, Inc.

Equipment installation and workforce training

NIA - National Institute on Aging

PROJECT SUMMARY Advancing our understanding of aging and aging-related diseases requires experimental models that capture the systemic complexity of the living organism. The laboratory mouse is an indispensable in vivo model for aging research, critically important for replicating the multifactorial interactions among genetics, physiology, environment, and behavior that drive conditions such as Alzheimer’s disease, cancer, and immunosenescence. While in vitro systems are valuable for dissecting cellular mechanisms, they lack the full biological context of an intact immune system, vascular and metabolic networks, and the microenvironmental and behavioral dynamics critical for both basic and translational aging research. Whole-animal systems remain essential for modeling disease mechanisms, progression, and therapeutic responses across the lifespan. Despite the central importance of murine models in aging biology, few institutions offer immersive, hands-on training in their use— especially with a focus on aging-related diseases. To address this gap, The Jackson Laboratory (JAX) proposes an R13 program entitled Essential Skills Development in the Use of the Laboratory Mouse as a Model of Aging- Related Diseases. This initiative will deliver expert-led, three-day traveling workshops directly to partner institutions, combining foundational instruction in animal care and ethics with tailored, rigorous, hands-on training aligned with the host site’s research priorities. By eliminating costs to participants and host institutions and deploying experienced instructors with mobile equipment kits, the program removes major barriers to access. To achieve these objectives, the proposed Specific Aims are: 1. Collaborate with institutional partners to tailor the aging-related workshop content to local needs and optimize access for regional participants, and 2. Facilitate participant engagement, skills development and career progression through the delivery of high-quality, immersive, hands-on workshops at partner institutions that are focused on aging-related murine research models and techniques. JAX is uniquely positioned to execute these traveling workshops and the anticipated impact of this program is that it will expand national capacity for aging-focused basic and translational research by developing essential technical skills in early-career scientists and increase awareness of, and readiness to engage with, complex in vivo models of aging. This proposal supports NIA’s mission to foster workforce development and advance research into the biological mechanisms and clinical challenges of aging.

OD - NIH Office of the Director

PROJECT SUMMARY Freeze-drying plays a vital role in pharmaceutical and biomedical development, yet researchers and collaborators in this region of Massachusetts currently lack equitable access to the flexible instrumentation required for early-stage formulation and method development. Each year, dozens of new lyophilized drug products are approved by the U.S. Food and Drug Administration, reflecting the field’s rapid growth and essential contributions to human health. The addition of the ATS SP Hull LyoStar 4.0, a research-scale freeze dryer, to the Core Research Facility at University of Massachusetts Lowell (UMass Lowell) will allow researchers to optimize freeze-drying protocols, reduce research delays, improve reproducibility, and retain innovation locally, advancing the university’s impact on translational science and regional economic development. The freeze dryer’s advanced temperature, vacuum, and pressure control, as well as integrated process monitoring tools, will support formulation testing, biological preservation, and material development across disciplines. These features are particularly important for UMass Lowell faculty working in biomedical engineering, chemistry, pharmaceutical sciences, plastics engineering, and environmental health, whose work spans peptide therapeutics, nanomedicine, drug delivery, and biopolymer design, areas that align directly with the mission of the NIH to improve public health through research. This equipment will also support hands-on workforce development, allowing undergraduates, graduate students, and postdoctoral researchers to gain practical experience with real- world biomanufacturing tools. It will be integrated into existing training programs and internship opportunities designed to prepare students for high-demand careers in the life sciences. Since its founding in 2013, UMass Lowell’s Core Research Facility has served as a trusted, shared-use platform for over 1,000 users annually, with a sustainable operating model that combines user fees and university investment. The LyoStar 4.0 will be seamlessly incorporated into this infrastructure, ensuring long-term access, technical oversight, and maximum impact. Its availability will help establish UMass Lowell as a regional hub for freeze-drying research and commercialization, supporting NIH’s mission to improve American’s health through innovation and scientific excellence.

National Institutes of Health

This Funding Opportunity will establish the NIH Blueprint for Neuroscience Research Network to Guide Foundational Research on Human Consciousness, leveraging a trans-NIH collaboration of 14 Institutes, Centers, and Offices dedicated to reducing the burden of nervous system disorders. Consciousness is central to numerous serious biomedical conditions, including coma, delirium, dementia, traumatic brain injury, stroke, sleep disorders, metabolic disorders, and seizures - conditions central to NIH's biomedical mission. Yet the neural mechanisms that support conscious states remain insufficiently understood, limiting clinicians ability to diagnose and treat patients effectively. Advancing foundational science on human consciousness will strengthen clinical decision-making and improve outcomes for patients with costly and hard-to-treat neurologic and systemic illnesses by:Detecting consciousness in minimally responsive patients to guide prognosis, treatment, and ethical decisions (e.g., organ harvesting).Improving understanding of consciousness in Alzheimer s disease, related dementias, and delirium.Investigating altered states in mental disorders to inform treatments.Identifying sentience and state transitions under anesthesia and during recovery.Advancing knowledge of sleep states and improving treatments for insomnia and other sleep disorders.Exploring non-sensory visual perception (e.g., hallucinations, aphantasia) to deepen insight into mental health.Evaluating therapeutic effects of consciousness-modulating interventions such as meditation, hypnosis, and neurostimulation.Applying New Approach Methodologies (NAMs) to study human consciousness.Despite its importance, biomedical research on consciousness lacks shared standards, resulting in fragmented efforts and limiting understanding of underlying neurocircuitry. To accelerate rigorous, reproducible, and ethically grounded research, this initiative will create a national interdisciplinary Research Network to strengthen and integrate consciousness-related neuroscience, rather than support discrete, hypothesis-driven projects. The Network will develop coordination frameworks, standards, and infrastructure, uniting expertise from neuroscience, neurology, psychiatry, psychology, anesthesiology, sleep and meditation research, computational science, AI, bioethics, and philosophy.The Network s goal is capacity building: developing and providing needed research resources to advance understanding of the neural mechanisms supporting conscious states. It will lead planning and consensus-building activities to:Harmonize operational definitions across consciousness research.Identify research settings, model systems, and experimental designs with the greatest potential.Evaluate indicators and measures of consciousness for diverse scientific approaches.Determine which measures best reflect preserved or perturbed neurobiological function.Address essential ethical considerations.To strengthen U.S. leadership and cultivate a highly trained workforce, the Network will provide interdisciplinary cross-training opportunities, such as workshops and visiting scholar programs, not feasible in siloed environments. This initiative will create resources that enable rigorous biomedical research on the neural mechanisms of conscious states, aligning with NIH's strategic priorities to improve population health and well-being.

National Institutes of Health

<p>This Funding Opportunity will establish the <strong>NIH Blueprint for Neuroscience Research Network to Guide Foundational Research on Human Consciousness</strong>, leveraging a trans-NIH collaboration of 14 Institutes, Centers, and Offices dedicated to reducing the burden of nervous system disorders. Consciousness is central to numerous serious biomedical conditions, including coma, delirium, dementia, traumatic brain injury, stroke, sleep disorders, metabolic disorders, and seizures - conditions central to NIH's biomedical mission. Yet the neural mechanisms that support conscious states remain insufficiently understood, limiting clinicians’ ability to diagnose and treat patients effectively. Advancing foundational science on human consciousness will strengthen clinical decision-making and improve outcomes for patients with costly and hard-to-treat neurologic and systemic illnesses by:</p><ul style="list-style-type:disc;"><li>Detecting consciousness in minimally responsive patients to guide prognosis, treatment, and ethical decisions (e.g., organ harvesting).</li><li>Improving understanding of consciousness in Alzheimer’s disease, related dementias, and delirium.</li><li>Investigating altered states in mental disorders to inform treatments.</li><li>Identifying sentience and state transitions under anesthesia and during recovery.</li><li>Advancing knowledge of sleep states and improving treatments for insomnia and other sleep disorders.</li><li>Exploring non-sensory visual perception (e.g., hallucinations, aphantasia) to deepen insight into mental health.</li><li>Evaluating therapeutic effects of consciousness-modulating interventions such as meditation, hypnosis, and neurostimulation.</li><li>Applying New Approach Methodologies (NAMs) to study human consciousness.</li></ul><p>Despite its importance, biomedical research on consciousness lacks shared standards, resulting in fragmented efforts and limiting understanding of underlying neurocircuitry. To accelerate rigorous, reproducible, and ethically grounded research, this initiative will create a national interdisciplinary Research Network to strengthen and integrate consciousness-related neuroscience, rather than support discrete, hypothesis-driven projects. The Network will develop coordination frameworks, standards, and infrastructure, uniting expertise from neuroscience, neurology, psychiatry, psychology, anesthesiology, sleep and meditation research, computational science, AI, bioethics, and philosophy.</p><p>The Network’s goal is capacity building: developing and providing needed research resources to advance understanding of the neural mechanisms supporting conscious states. It will lead planning and consensus-building activities to:</p><ul><li>Harmonize operational definitions across consciousness research.</li><li>Identify research settings, model systems, and experimental designs with the greatest potential.</li><li>Evaluate indicators and measures of consciousness for diverse scientific approaches.</li><li>Determine which measures best reflect preserved or perturbed neurobiological function.</li><li>Address essential ethical considerations.</li></ul><p>To strengthen U.S. leadership and cultivate a highly trained workforce, the Network will provide interdisciplinary cross-training opportunities, such as workshops and visiting scholar programs, not feasible in siloed environments. This initiative will create resources that enable rigorous biomedical research on the neural mechanisms of conscious states, aligning with NIH's strategic priorities to improve population health and well-being.</p>

Centers for Disease Control-GHC

CDC is working with the Tanzania government to meet key International Health Regulations requirements through implementation of the Global Health Security Agenda (GHSA). Tanzania completed the Joint External Evaluation and launched a costed National Action Plan for Health Security based on a multi-sectorial approach. This NOFO supports programs/activities in the following areas: strengthening biosurveillance systems networked to information sharing platforms to predict and identify health threats, including at points of entry; expanding emergency capacity through national and subnational emergency operation centers; enhancing national laboratory capabilities and applying biosafety and biosecurity best practices for accurate, and reliable detection of outbreaks, antimicrobial resistance and emerging zoonotic diseases; increasing timely and transparent reporting of disease emergencies and threats to relevant national and international authorities; and developing a functional biosurveillance workforce with trained disease detectives and laboratory scientists.

Centers for Disease Control-GHC

The CDC office in Ethiopia was established in 2001 and works closely with the Ministry of Health (MOH), the Ethiopian Public Health Institute (EPHI), and other Government of Ethiopia (GOE) agencies to develop the capacity to prevent, detect, and respond to priority diseases. In 2014, CDC began coordination with the GOE to build Ethiopia's capacity to achieve the International Health Regulation (IHR) targets through implementing the Global Health Security Agenda. The initial road map was developed with multi-sector partners in 2015, and the multi-sector collaboration is proving successful with over 500 trained in field epidemiology, a national public health emergency operations center activated for outbreaks and expanding diagnostic and surveillance capacity. In 2020, CDC has continued to support and advance GOE's ability to detect, respond and manage multiple concurrent outbreaks that plague Ethiopia on a yearly basis through the collaboration of multiple implementing partners including EPHI. CDC will continue to empower the GOE to strengthen their response efforts to public health emergencies by building on the 2020-2025 projects focused on CDC's Global Health Security Framework. The strategic focus areas of CDC's work to achieve Ethiopia's IHR compliance are the following: (1) Laboratory, (2) Workforce Development, (3) Surveillance, (4) Emergency Response and Management, (5) Antimicrobial Resistance (6) Immunization, (7) Health Information System Strengthening.

Centers for Disease Control-GHC

This NOFO aims to enhance Senegal's public health infrastructure to prevent, detect, and respond to infectious disease threats through implementing partners. The initiative focuses on strengthening public health surveillance systems, including community-based surveillance, improving laboratory networks, and enhancing workforce training. The goal is to build sustainable, resilient health security infrastructure, aligning with Global Health Security Agenda (GHSA) objectives. Partners will collaborate to promote cross-sectoral coordination and foster innovative approaches.

U.S. National Science Foundation

The Geospace Section of the NSF Division of Atmospheric and Geospace Sciences (AGS) offers funding for the creation of new tenure-track faculty positions within the disciplines that comprise the AGS Geospace programs to ensure their vitality at U.S. universities and colleges. The aim of the Faculty Development in geoSpace Science (FDSS) is to integrate topics in geospace science including solar and space physics and space weather research into natural sciences or engineering or related departments at U.S. institutions of higher education (IHE). FDSS also stimulates the development of undergraduate or graduate programs or curricula capable of training the next generation of leaders in geospace science. Geospace science is interdisciplinary in nature and FDSS awardees will be expected to establish partnerships within multiple parts of the IHE. NSF funding will support the salary, benefits and training of the newly recruited tenure-track FDSS faculty member for a duration of up to five years with a total award amount not to exceed $1,500,000.Growing diversity in the geospace science workforce and institutions is a community priority, yet relatively few geospace science research and training opportunities are available at minority-serving institutions (MSIs) and emerging research institutions (ERIs). One of NSF s priorities is to improve representation in the scientific enterprise. FDSS aims to bolster long-term investments in geospace science at a broad range of U.S. IHEs, including MSIs and ERIs. This solicitation offers a track for all qualified U.S. IHEs and additionally, a separate track for proposal submissions from MSIs and ERIs.

NIMH - National Institute of Mental Health

PROJECT SUMMARY/ABSTRACT Autistic youth are far more likely to experience depression and suicidal thoughts and behaviors than their non- autistic peers, yet few autistic youth receive appropriate treatment. Untreated depression is associated with adverse short- (e.g., school refusal) and long-term outcomes (e.g., poor physical health) that impair quality of life. Families of autistic youth with depression encounter barriers to care including significant clinician shortages and high clinician uncertainty in treating this population. Clinicians frequently decline referrals due to limited autism training and few evidence-based treatments. Though Cognitive-Behavioral Therapy (CBT) is a leading intervention for depression in non-autistic youth, it has not been rigorously studied in autism. Given that autism- adapted CBT consistently outperforms standard CBT for anxiety and obsessive-compulsive disorder, it is likely that autism-adapted CBT for depression may be effective in treating symptoms; however, this remains largely underdeveloped and untested. To being to address this gap, we partnered with autistic stakeholders to develop Cognitive Behavioral Therapy for Depression in Autistic Youth (CBT-DAY) and tested the preliminary feasibility and acceptability of CBT-DAY in a pilot nonrandomized trial, with promising initial findings. CBT-DAY targets emotional reactivity, negative self-esteem, and autism self-knowledge in youth to improve depressive symptom severity. However, CBT-DAY has not been evaluated in a larger randomized controlled trial and when delivered by clinicians with limited autism training. Therefore, in this study, we seek to examine the feasibility, acceptability, and initial effectiveness of CBT-DAY and its associated clinician training model for verbally-fluent (Verbal IQ≥70) autistic youth with depression (11-17 years old) served in outpatient clinics. In the first phase of the study, we aim to develop a CBT-DAY clinician training model for clinicians with limited autism training based on feedback from 35 stakeholders including autistic youth with depression and their parents, clinicians, and clinic leaders. In the second phase, we will conduct a hybrid type 1 effectiveness-implementation trial with 60 autistic youth (11- 17 years old) with depression, 60 of their parents, and 20 clinicians with limited autism training in clinical settings, comparing CBT-DAY versus treatment-as-usual (TAU). We will test the initial feasibility, acceptability, and effectiveness of CBT-DAY in improving youth depressive symptom severity. In the final phase of the study, we will collect mixed methods data (i.e., interviews, surveys) on implementation outcomes (i.e., feasibility, acceptability, fidelity) and contextual factors influencing CBT-DAY implementation and sustainment from the recruited families, clinicians, and organizational leaders. Findings will inform future studies that scale up CBT- DAY and improve its implementation and sustainability in clinical settings. This R34 project has important clinical implications, as findings may support the testing and implementation of CBT-DAY and its associated clinician training model to improve outcomes for autistic youth with depression and increase the service workforce.

Health and Human Services Department

This notice is to inform the public that the Substance Abuse and Mental Health Services Administration (SAMHSA) is supporting an administrative supplement in scope of the parent award for one eligible grant recipient funded in FY 2024 under the Prevention Technology Transfer Centers Cooperative Agreements, Notice of Funding Opportunity (NOFO) SP-24-002. The recipient may receive up to $1,198,000. The recipient has a project end date of September 29, 2029. The supplemental funding supports the implementation of a substance use prevention fellowship program. The program will be developed in collaboration with national-level state and community organizations and aims to develop and sustain a highly trained and knowledgeable workforce of prevention professionals drawn from communities that have faced challenges in maintaining sufficient prevention staffing to meet the full scope of community needs. Fellows will be equipped to understand, apply, and exemplify the core principles and evidence-based best practices of substance use prevention. This program will support a state level fellowship program and a community level program. This program will also prepare fellows to achieve certification from the International Certification and Reciprocity Consortium (IC&RC). The supplemental funding will support fellows in the following areas: hands-on experience working in state agencies and community organizations while supported by agency mentors; virtual and in-person training in professional development and prevention; acquiring proficiency in appropriate core competencies in preparation for the Certified Prevention Specialist exam; developing management and leadership skills; and preparing for potential employment opportunities within the prevention field.

Health and Human Services Department

This notice is to inform the public that the Substance Abuse and Mental Health Services Administration (SAMHSA) is supporting an administrative supplement in scope of the parent award for one eligible grant recipient funded in FY 2024 under the Prevention Technology Transfer Centers Cooperative Agreements, Notice of Funding Opportunity (NOFO) SP-24-002. The recipient may receive up to $1,198,000. The recipient has a project end date of September 29, 2029. The supplemental funding supports the implementation of a substance use prevention fellowship program. The program will be developed in collaboration with national-level state and community organizations and aims to develop and sustain a highly trained and knowledgeable workforce of prevention professionals drawn from communities that have faced challenges in maintaining sufficient prevention staffing to meet the full scope of community needs. Fellows will be equipped to understand, apply, and exemplify the core principles and evidence-based best practices of substance use prevention. This program will support a state level fellowship program and a community level program. This program will also prepare fellows to achieve certification from the International Certification and Reciprocity Consortium (IC&RC). The supplemental funding will support fellows in the following areas: hands-on experience working in state agencies and community organizations while supported by agency mentors; virtual and in-person training in professional development and prevention; acquiring proficiency in appropriate core competencies in preparation for the Certified Prevention Specialist exam; developing management and leadership skills; and preparing for potential employment opportunities within the prevention field.

Health and Human Services Department

This notice is to inform the public that the Substance Abuse and Mental Health Services Administration (SAMHSA) is supporting an administrative supplement in scope of the parent award for one eligible grant recipient funded in FY 2024 under the Prevention Technology Transfer Centers Cooperative Agreements, Notice of Funding Opportunity (NOFO) SP-24-002. The recipient may receive up to $1,198,000. The recipient has a project end date of September 29, 2029. The supplemental funding supports the implementation of a substance use prevention fellowship program. The program will be developed in collaboration with national-level state and community organizations and aims to develop and sustain a highly trained and knowledgeable workforce of prevention professionals drawn from communities that have faced challenges in maintaining sufficient prevention staffing to meet the full scope of community needs. Fellows will be equipped to understand, apply, and exemplify the core principles and evidence-based best practices of substance use prevention. This program will support a state level fellowship program and a community level program. This program will also prepare fellows to achieve certification from the International Certification and Reciprocity Consortium (IC&RC). The supplemental funding will support fellows in the following areas: hands-on experience working in state agencies and community organizations while supported by agency mentors; virtual and in-person training in professional development and prevention; acquiring proficiency in appropriate core competencies in preparation for the Certified Prevention Specialist exam; developing management and leadership skills; and preparing for potential employment opportunities within the prevention field.

Health Resources and Services Administration

<p>The purpose of the Fiscal Year (FY) 2027 State and Regional Primary Care Association (PCA) program is to develop and deliver technical assistance (TA) that supports existing and potential Health Center Program award recipients and look-alikes (LALs), hereafter referred to as health centers, both directly and collaboratively with other HRSA-funded TA programs. PCAs will improve the health of medically vulnerable individuals and communities by:</p><ul><li data-list-item-id="ec72f7d87f991e4eec0b8d0b6cd0e8268">Increasing access to high-quality preventive and primary health care services.</li><li data-list-item-id="ebe3ab7a472d648581da1fd5aa4f01d6c">Improving chronic disease prevention and management to enhance the overall health of communities.</li><li data-list-item-id="e913f0580d7c5f4c00d56c1232ac1777a">Recruiting, retaining, and training a health center workforce.</li><li data-list-item-id="ead5ae93ef8d5ff1a76a8c7e80c60b80d">Preparing for, responding to, and recovering from emergent health events.</li><li data-list-item-id="e723bfeee3b8dfaa2c571d085c80c1b63">Implementing payer strategies, including value-based care delivery, to ensure high functioning, financially sustainable health centers.</li><li data-list-item-id="e84c1a2f965bd2854060a48ed22c4d086">Accelerating data-informed improvements to improve operations and clinical quality.&nbsp;</li></ul>

Florida CareerSource

Florida CareerSource administers workforce development grants funding job training, apprenticeships, incumbent worker training, and employer-based training programs in FL.

Florida Department of Economic Opportunity

The Job Growth Grant Fund supports public infrastructure and workforce training projects to create jobs and stimulate private investment throughout Florida.

U.S. National Science Foundation

Focus On Recruiting Emerging Climate and Adaptation Scientists and Transformers (FORECAST) seeks to facilitate the transition from status quo graduate career preparation to a student-centered model with a particular emphasis on building entrepreneurial and innovation capacity at emerging research institutions (ERIs). Transformers are scientists ready to tackle the challenges the nation and world are facing due to climate change. This opportunity will adopt the spirit of multiple directives for the research community; for example, the National Academies of Sciences, Engineering, and Medicine (NASEM) report on Earth System Scienceand the Advisory Committee for Environmental Research and Education report on Engaged Research. These directives call on the research enterprise to support the building of a robust scientific workforce ready to work with communities in addressing societal challenges. Through convergence research approaches to address societal challenges, the transdisciplinary researchers engaged in FORECAST will foster community resilience and the translation of research outcomes for societal benefits, as well as gain a broader understanding of the governmental context related to these issues. A new generation of scientists trained in "engaged research" will be expected to have a national impact in communities that may be disproportionately affected by climate change impacts. The program will build cohorts of innovative scholars from the full spectrum of diverse talent at emerging research institutions to include groups historically excluded in science, technology, engineering and mathematics (STEM). Participants, who are senior students in undergraduate programs and students who are in master's degree programs, will be supported through intentional professional development activities. FORECAST participants must be US citizens or permanent residents. FORECAST proposals will fall into three categories: Track 1, Track 2, and FORECAST Planning grants. Track 1 will support one Coordination Hub, to coordinate support for rising seniors from emerging research institutions (ERIs) or historically excluded and underserved groups as part of a national cohort to participate in structured professional development opportunities. Track 2 projects will support cohorts of Master's degree students at ERIs. Mentorship and capacity building should be central to the cohort approach. FORECAST Planning grant proposals will build capacity at ERI institutions and with the appropriate partners to undertake the activities necessary to establish a future FORECAST track 2 cohort.

NIGMS - National Institute of General Medical Sciences

Project Summary The Chemistry-Biology Interface (CBI) training program is a new predoctoral training program at Brown University that will equip students with the knowledge, skills, and attitudes that will allow them to successfully conduct rigorous and reproducible research and to be successful, independent, professionals trained at the interface of chemistry and biology. The rationale is that our 26 faculty trainers and program have the capability to advance biomedical sciences by providing training at the chemistry-biology interface. The training objectives for this program are to: (1) build and sustain an interdisciplinary and collaborative training environment; (2) train PhD students in 10 core competencies; (3) graduate PhD students with a time-to-degree of ≤5 years and completion rate >90%; and (4) train faculty mentors to engage in productive mentoring relationships that optimize the success of the mentors and their trainees alike. The ten core competencies will ensure that trainees have broad conceptual knowledge of chemical biology along with deep knowledge of a specific field and skills in critical thinking, responsibly conducting rigorous and reproducible research, quantitative analysis of data, collaboration, communication, and leadership to support their career development. The CBI training program will support 8 trainees per year and provide structured coursework and a cohesive support framework enabling students to explore research and educational opportunities at the chemistry-biology interface to pursue careers in the biomedical workforce. Trainees are selected from seven doctoral programs: Chemistry, Engineering, Biomedical Engineering and a strategic group of four programs within the Division of Biology and Medicine. Trainees learn the principles and techniques of the discipline with courses in chemical biology, methods, quantitative analysis, and a CBI elective. The training program incorporates multiple professional development and networking opportunities including: required monthly meetings for research in progress presentations, discussions on rigor and reproducibility, and RCR refresher training; an experiential interdisciplinary research opportunity to strengthen training at and across the interface of chemistry and biology; peer mentoring; career exploration opportunities; and an annual symposium for trainees to present their research and network with the local CBI community and prominent scientists in chemical biology external to Brown. CBI trainees will be supported during years 2 and 3 of their graduate training but participate in the program until graduation.

NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development

Project Summary Today's biomedical challenges are complex, requiring truly innovative and interdisciplinary solutions. The Foundational Quantitative and Experimental Predoctoral Training in Neurosciences (FQuETPN) at the University of Washington (UW) will offer a multidisciplinary education in fundamental neuroscience that will nurture a close-knit group of first and second year predoctoral trainees who are equipped for success as the next generation of scientists in the biomedical workforce. Trainees will be encouraged not only to expand their technical and intellectual skills by partnering with their chosen faculty mentors, but also to take advantage of a broad range of educational experiences aimed at preparing them to attain their future career goals. Our program is organized around three interactive pillars: A Research Excellence Pillar will enrich, in significant and new ways, the research training of students with new training modules that ensure outstanding foundational training in ways that track the changing landscape of neuroscience research. The Quantitative Excellence Pillar will provide new opportunities for training in experimental design, statistical methodology, large scale data collection, high dimensional and computational analysis of neuroscience data. A Community and Professional Development Pillar will ensure that all fellows truly thrive in our program as they make new discoveries and transform to become leaders in their fields. A strategic combination of relational and transactional professional development activities will increase the likelihood that trainees will pursue academic and professional careers in neuroscience. The proposed program will stand on the shoulders of an existing, outstanding, neuroscience research community and graduate education program at UW, but will extend the training experience in several domains that focus on quantitative and experimental rigor and collaborative, interdisciplinary interactions. The FQuETPN curriculum includes essential courses from cellular neurobiology to cognition, supplemented with innovative professional development in grant writing, public speaking, bioethics, and navigating the neuroscience culture. In addition, the program will provide numerous activities that bring graduate students, postdocs, and faculty together to discuss current topics in neuroscience in an informal but focused setting that encourages students to express their opinions and ask questions. The training program will consist of six two- year, graduate student appointments. In each year, three 1st and three 2nd year students will be enrolled in the FQuETPN. Faculty mentors and a Student Advancement Committee oversee student progress, ensuring tailored guidance for success. Our training program will ensure that graduates are well-prepared for independent research and research-related careers in neuroscience.

NIDA - National Institute on Drug Abuse

This K24 Midcareer Investigator Award in Patient-Oriented Research (POR) will provide protected time for Oluwaseun Falade-Nwulia, MBBS, MPH, Associate Professor of Infectious Diseases at Johns Hopkins University, to expand a structured, sustainable mentoring program for trainees and early-stage investigators committed to improving health outcomes for people who use drugs (PWUD). Dr. Falade-Nwulia is a clinicianscientist with expertise in infectious disease and addiction care whose research applies implementation science to identify determinants of care engagement and to design, implement, and evaluate strategies that increase uptake of evidence-based interventions; including HIV pre-exposure prophylaxis (PrEP), antiretroviral therapy (ART), direct-acting antivirals (DAAs) for hepatitis C virus (HCV), and medications for opioid use disorder (MOUD). Her mentoring portfolio focuses on investigators whose work addresses the intersecting epidemics of HIV, HCV, substance use disorders (SUD), and overdose among PWUD. Through this K24, Dr. Falade-Nwulia will expand mentoring in POR that integrates behavioral economics, implementation science, and economic evaluation to improve uptake and continuity of care within integrated HIV and SUD care models. Mentoring activities will include longitudinal career development planning, structured works-in-progress sessions, and collaborative research engagement. The mentoring aims are: (1) to develop the next generation of independent physician-scientists and health services researchers equipped to conduct rigorous POR focused on PWUD, and (2) to establish the Nudging Integrated Care and Engagement (NICE) Program, a structured mentoring platform that leverages the robust research and training infrastructure of the Johns Hopkins University School of Medicine and the Bloomberg School of Public Health. The K24-supported research platform will advance the field by: (1) integrating behavioral-economics-informed implementation strategies (e.g., defaults, friction-reduction, incentives, commitment devices, and socialinfluence approaches) into existing service delivery models to address behavioral drivers of under-utilization of HIV prevention and SUD treatment among PWUD; and (2) conducting rigorous mixed-methods and costeffectiveness evaluations to generate scalable, policy-relevant strategies. This award will also allow Dr. Falade-Nwulia to obtain advanced training in behavioral economics and economic evaluation, further enhancing her POR program and capacity to mentor early-stage investigators. Ultimately, this K24 award will accelerate the development of a skilled workforce focused on improving HIV and SUD outcomes among PWUD, while advancing implementation science to optimize integrated care delivery in community-based and rural settings in Maryland and beyond.