Search Grants — Free, No Account Required

MI Dept of Agriculture & Rural Development

Grants for specialty crops, food safety, and rural economic development.

Michigan Department of Agriculture and Rural Development

MDARD provides grants to farmers, agribusinesses, food banks, and rural organizations for agricultural development, local food systems, food safety, and rural community economic development across Michigan.

NCI - National Cancer Institute

Title: Microfluidic Isolation and Deep Learning-based Profiling of Subtypes of Circulating Tumor Cells during Epithelial Mesenchymal Transition Project Summary/Abstract Circulating tumor cells (CTCs) are highly heterogeneous and contain many cellular subpopulations. It is known that specific CTC subpopulations, rather than the whole, are responsible for cancer metastases. Recently, epithelial mesenchymal transition (EMT) of adherent epithelial cells to a migratory mesenchymal state has been implicated in tumor metastasis. CTCs isolated from cancer patients exhibit dynamic changes in epithelial and mesenchymal composition, and serial CTC monitoring in those patients suggested an association of EMT in CTCs. Emerging microfluidic technologies have shown great promise for the complete capture of the CTCs population with high yield and enhanced purity. However, most existing devices simply isolate all CTCs in blood without resolving them into distinct subpopulations: isolation of CTC populations with specific EMT markers remains a significant challenge. Consequently, epithelial-mesenchymal plasticity of CTCs during cancer progression is largely unknown, preventing researchers from acquiring true insights into the metastatic potential of CTCs. In the R15 project, we propose to develop the HU microchip platform for isolation and profiling of CTCs in pre-clinical settings, with the focus on detecting and understanding features associated with CTC subtypes during the course (or intermediate states) of EMT. To do so, we will isolate CTCs and explore deep learningbased profiling platforms using both micro and nanometer-scale features found from microscope images obtained from our HU microfluidic devices. This is expected to achieve super-high accuracy for profiling CTC subtypes with varied cell plasticity (i.e., more “epithelial” or more “mesenchymal” type). Building on the success of this project, we expect to develop an integrated system comprising 1) a user-friendly HU microchip for highly efficient isolation of CTCs from blood samples, and 2) an AI-based image analysis platform that can identify CTC subtypes for monitoring cancer progression and support cancer diagnosis and treatment. CTCs with defined EMT stages generated from the NSG mouse model will used to provide critical ground-truth information for validation of the proposed AI model, which cannot be accomplished using other alterative models. This project is strongly integrated with an educational plan to expose undergraduates to advanced experiments in the areas of biomedical engineering and cancer research. It is our belief that involving all students in cutting-edge research will have a significant positive impact on attracting and retaining students in science and healthcare fields. In this grant, we will provide research opportunities for 6 undergraduate students and 1 graduate to learn advanced knowledge on cancer biology, obtain hands-on experience in microfabrication and biological assays. Texas Tech University (TTU) is located in Lubbock, a rural area in northwestern Texas and TTU has been classified as "Tier 1" status in 2016. Due to historical and geographical reasons, life sciences research is not a strength for TTU, and TTU is not a recipient of major NIH grants. This R15 grant will strengthen our research and training at TTU and help us to reach our goal to be one of the best bioengineering programs in Texas.

Minnesota Department of Agriculture

The MDA provides grants to farmers, food system organizations, and rural communities for sustainable agriculture, local food systems, beginning farmer support, agricultural marketing, and rural economic development across Minnesota.

Montana Department of Commerce

The Big Sky Economic Development Trust Fund provides grants and loans to Montana communities for infrastructure and economic development projects that create or retain jobs, with priority given to projects in rural and distressed areas.

NCI - National Cancer Institute

PROJECT SUMMARY/ABSTRACT The long-term objective of this K99/R00 application is to develop Dr. Kelsey Day’s ability to become a leader in community-based physical activity research and cancer prevention, particularly through the development of sustainable, multilevel, and participatory solutions. In the K99 phase of the project, Dr. Day will receive support in meeting four training objectives that will facilitate her transition to an independent investigator and expand her knowledge in key content areas that are highly relevant to her long-term career goals. First, she will expand her knowledge of text message and mHealth intervention approaches to increasing physical activity. Second, she will learn how to analyze objective device-measured physical activity data. Third, she will gain theoretical and practical knowledge of community based participatory research methodology. Finally, Dr. Day will obtain advanced training in qualitative research methods. In the K99 phase, Dr. Day will also initiate the research aims of a multilevel, faith-based project focused on physical activity. In Aim 1, she will use a participatory design process to convene focus groups of rural church members to adapt a rural physical activity text message intervention with spiritual content and tailored physical activity feedback. Concurrently, in Aim 2, she will conduct workshops with leaders from rural churches who are paired with a leader from their local Parks and Recreation departments to: 1) establish partnerships; 2) use a participatory approach to adapt evidence-based intervention strategies to increase physical activity; 3) determine barriers and facilitators to the selected strategies within the church/Parks partnership. In Aim 3 (R00 phase), Dr. Day will deliver the multilevel intervention (individual text message intervention, plus church/Parks strategies) to a pilot group of rural churches to evaluate feasibility indicators, including: limited efficacy (changes in Fitbit-measured physical activity among rural churchgoers); acceptability; implementation; and demand. The proposed research seeks to address critical rural health disparities and to promote rural cancer prevention by increasing physical activity opportunities and capacity through a sustainable, multilevel approach. The project is consistent with the NCI’s mission of conducting cancer research that helps individuals across the country live longer and healthier lives, as well as the NCI’s strategic focus on rural cancer disparities. Dr. Day proposes to pursue these training objectives and begin the proposed research aims with the support of the University of Virginia Comprehensive Cancer Center and the Department of Public Health Sciences in the University of Virginia School of Medicine. This environment offers an optimal setting, including research support and resources, to assist her in reaching her training and research objectives.

National Association of Development Organizations

Rural transportation planning and infrastructure development

NC Department of Agriculture and Consumer Services

The NC Department of Agriculture provides grants to farmers, agribusinesses, food banks, and rural organizations for agricultural development, food system infrastructure, farmland preservation, and rural community support.

NC Department of Commerce

The NC Department of Commerce funds rural economic development initiatives, community infrastructure, business recruitment, and job creation programs targeting economically distressed counties across North Carolina.

Nevada Arts Council

Community Arts Development grants fund projects that bring arts programming to underserved Nevada communities, including rural areas and tribal communities, promoting cultural expression and community engagement through the arts.

New Jersey Department of Agriculture

The NJDA provides grants to farmers, agricultural organizations, and rural communities for farmland preservation, agricultural development, food access programs, and rural economic development across New Jersey.

Education Department

The Employment and Training Administration at the U.S. Department of Labor (DOL) is soliciting applications in support of the administration of the Fund for the Improvement of Postsecondary Education (FIPSE)--Rural Postsecondary and Economic Development Grant Program (RPED), Assistance Listing Number (ALN) 84.116W, on behalf of the U.S. Department of Education (ED).

Health and Human Services Department

The Rural Communities Opioid Response Program--Behavioral Health Care Technical Assistance (RCORP-TA) strengthens, through technical assistance, rural organizations' capacity to develop multi- sector consortia that can plan, implement, and sustain programs that improve access to and quality of behavioral health care services, including substance use disorder/opioid use disorder services. This funded extension extends RCORP-TA's one cooperative agreement award recipient from cohort fiscal year 2022, HRSA-22-064, for a one-time 1- year period (September 1, 2026, through August 31, 2027). The current recipient, JBS International, Inc (U6BRH32364) was funded for a 4-year period of performance (September 1, 2022, through August 31, 2026).

Health and Human Services Department

The Rural Communities Opioid Response Program--Behavioral Health Care Technical Assistance (RCORP-TA) strengthens, through technical assistance, rural organizations' capacity to develop multi- sector consortia that can plan, implement, and sustain programs that improve access to and quality of behavioral health care services, including substance use disorder/opioid use disorder services. This funded extension extends RCORP-TA's one cooperative agreement award recipient from cohort fiscal year 2022, HRSA-22-064, for a one-time 1- year period (September 1, 2026, through August 31, 2027). The current recipient, JBS International, Inc (U6BRH32364) was funded for a 4-year period of performance (September 1, 2022, through August 31, 2026).

Agriculture Department

The Under Secretary for Rural Development (RD or Agency) is seeking applications for the Strategic Economic and Community Development (SECD) priority, as reauthorized by Section 6401 of the Agriculture Improvement Act of 2018 (2018 Farm Bill) for projects that support multi-jurisdictional and multi-sectoral strategic community investment plans. In Fiscal Year (FY) 2026, the covered RD programs will implement SECD by reserving loan and grant funds from the appropriations of the programs covered by this funding priority. This notice describes the requirements by which RD will consider projects eligible for covered programs' reserved funds and information needed to submit an application. Information on FY 2026 funding amounts can be found under SUPPLEMENTARY INFORMATION, section B. Federal Award Information of this notice.

Agriculture Department

The Rural Utilities Service (RUS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of applications under the Community Connect Grant Program (CCG) for fiscal year (FY) 2026. In future years this funding opportunity will only be announced on the Agency website and grants.gov, without a Federal Register notice. Therefore in future years, neither the funding opportunity nor reference to the funding opportunity in grants.gov will appear in the Federal Register. Please make a note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Business-Cooperative Service (RBCS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of grant applications under the Delta Health Care Services Grant Program (DHCS). In future years this funding opportunity will only be announced on the Agency website and grants.gov, without a Federal Register notice. Therefore, in future years, neither the funding opportunity nor reference to the funding opportunity in grants.gov will appear in the Federal Register. Please make note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Utilities Service (RUS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of applications under the Distance Learning and Telemedicine (DLT) grant program for fiscal year (FY) 2026. In future years this funding opportunity will only be announced on the Agency website and grants.gov, without a Federal Register notice. Therefore in future years, neither the funding opportunity nor reference to the funding opportunity in grants.gov will appear in the Federal Register. Please make a note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Business-Cooperative Service (RBCS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of loan applications under the Intermediary Relending Program (IRP). In future years, this funding opportunity will only be announced on the Agency website without a Federal Register notice. Therefore, in future years, neither the funding opportunity nor reference to the funding opportunity will appear in the Federal Register. Please make note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Housing Service (RHS or Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA), announces the availability of funding for applications under its Native Community Development Financial Institution (NCDFI) Relending Demonstration Program for fiscal year (FY) 2025. The purpose of this notice is to announce the opening and closing dates for receipt of applications for the NCDFI Relending Demonstration Program from eligible applicants, as well as submission requirements. These loans will be made to qualified NCDFIs to relend funds to low- and very low- income ultimate recipients to acquire, build, rehabilitate, improve, or relocate dwellings on Tribal Land in rural areas. This program has the amount of $4,630,000 available for FY 25. Applicants are responsible for any expenses incurred in developing their applications.

Agriculture Department

The Rural Business-Cooperative Service (RBCS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of applications under the Rural Business Developmental grant program for fiscal year (FY) 2026. In future years this funding opportunity will only be announced on the Agency website and grants.gov, without a Federal Register notice. Therefore, in future years, neither the funding opportunity nor reference to the funding opportunity in grants.gov will appear in the Federal Register. Please make a note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Business-Cooperative Service (RBCS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA) is issuing a Notice of Funding Opportunity (NOFO) to announce acceptance of applications for passenger Rural Transportation systems under the Rural Business Developmental grant program for fiscal year (FY) 2026. In future years this funding opportunity will only be announced on the Agency website and grants.gov, without a Federal Register notice. Therefore, in future years, neither the funding opportunity nor reference to the funding opportunity in grants.gov will appear in the Federal Register. Please make a note of this change in location of the funding announcement in your records.

Agriculture Department

The Rural Housing Service (RHS or the Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA), announces the acceptance of applications under the Rural Community Development Initiative (RCDI) program for fiscal year (FY) 2025. Approximately $5 million in funding is available for FY 2025. These grants will be made to qualified Intermediary organizations that will provide financial and Technical assistance to Recipients to develop their capacity and ability to undertake projects related to housing, community facilities, or community and economic development that will support the community. Applicants are responsible for any expenses incurred in developing their applications.

Agriculture Department

The Rural Business-Cooperative Service (RBCS or Agency), a Rural Development (RD) agency of the United States Department of Agriculture (USDA), invites applications for loans and grants under the Rural Economic Development Loan and Grant Programs (REDLG or Programs) for fiscal year (FY) 2026, subject to the availability of funding. This notice is being issued prior to the passage of a FY 2026 Appropriations Act, which may or may not provide funding for this program, to allow applicants sufficient time to leverage financing, prepare and submit their applications, and give the Agency time to process applications within FY 2026. Based on FY 2025 appropriated funding and current budget situation, the Agency estimates that approximately $50,000,000 for Loans and $10,000,000 for Grants will be available for FY 2026. Successful applications will be selected by the Agency for funding and subsequently awarded to the extent that funding may ultimately be made available through appropriations. All applicants are responsible for any expenses incurred in developing their applications.