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Grants for Basic Research in Glomerular Diseases (R01)

open

National Institutes of Health

Purpose. The Division of Kidney, Urologic and Hematologic Diseases (DKUHD) of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) invites applications from new or established investigators to pursue basic exploratory investigations of glomerular disease, which would foster development of new ideas enhancing the understanding of disease detection, pathogenesis, pre-emption and / or treatment. Mechanism of Support. This FOA will utilize the NIH Research Project Grant (R01) award mechanism Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the mechanism numbers, quality, duration, and costs of the applications received. Eligible Institutions/Organizations: Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations Eligible Project Directors/Principal Investigators (PDs/PIs). Individuals with the skills, knowledge, and resources necessary to carry out the proposed research are invited to work with their institution/organization to develop an application for support. Individuals from underrepresented racial and ethnic groups as well as individuals with disabilities are always encouraged to apply for NIH support. Number of Applications. Applicants may submit more than one application, provided each application is scientifically distinct. Renewals and Resubmissions. Applications can be renewed by competing for additional project periods. Applicants may submit a resubmission application, but such application must include an Introduction addressing the previous peer review critique (Summary Statement).

rolling
Healthhealthcare

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Healthcare Expansion Loan Program II (HELP II)

open

State Treasurer's Office

Eligibility -Must be a health facility as defined in the Authority's Act (Section 15432(d) of the California Government Code) -Must be a non-profit 501(c)(3) corporation and qualify as a small or rural health facility or public health facility (e.g., district hospital) as defined in the Authority's Act (Section 15432(e) of the California Government Code)  -Small facilities must have annual gross revenues of $30 million or less (no revenue limit for rural facilities or district hospitals) -Must be licensed by the State of California, typically through the Department of Health Care Services, Public Health, or Social Services -Must have been in existence for at least three years, providing the same types of services -Must demonstrate evidence of discal soundness and the ability to meet the terms of the proposed loan -Facility must be certified, organized, maintained and operated for the diagnosis, care, prevention, and treatment of human illness, or physical, mental, or developmental disability, including convalescence and rehabilitation and including during care during and after pregnancy Use of Funds Funds may be used for: -Purchase, construction, renovation, or remodeling of real property -Purchase equipment and furnishings -Perform feasibility studies, site tests, and surveys associated with real property -Pay permit fees, architectural fees, and pre-construction costs -Refinancing existing debt Loan Terms -Minimum loan amount of $25,000 -Maximum loan amount of $1.5 million ($1 million for refinancing existing debt) -Interest rate of 3% (4% for refinancing existing debt) -Maximum loan maturity depends on use of funds.  Between 5 years for equipment and furnishings and 20 years for the purchase, construction and renovation of real property (15 years for refinancing existing debt) -Gross revenue pledge, as well as a lien on the equipment or property, is required -Maximum loan-to-value ratio of 95% -Borrowers must contribute a minimum of 5% (in the form of cash or documented project expenditures) toward project costs -Proforma debt service coverage of at least 1.0x Fees -$50 non-refundable application fee -Initial fee of 1.25% of the loan amount payable at closing -No ongoing program fees Required Documentation -Three most recent fiscal years of audited financial statements -Proof of adequate property and business insurance  

$25K – $1.5M
Rolling
health & human services

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Hypersensitivity Pneumonitis - Early Identification and Mechanisms of Disease (R01)

open

National Institutes of Health

-Purpose. To address the importance of continued research about forms of Hypersensitivity Pneumonitis Lung Diseases, especially the early recognition of disease and a better understanding of immune mechanisms involved in the cause and pathogenesis. -Mechanism of Support. This FOA will utilize the R01 mechanism. This R01 mechanism will support different types of projects including pilot and feasibility studies; small, self-contained research projects; and development of new research technology. -Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State Government; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Other(s): Eligible agencies of the Federal government; Faith-based or community based organizations.

rolling
Healthhealthcare

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Image-Guided Cancer Interventions (SBIR [R43/R44])

open

National Institutes of Health

Purpose. This Funding Opportunity Announcement (FOA) supports the development and clinical validation of systems for image-guided interventions (IGIs) for cancer. Specifically, the goals of this program are to provide support for: the development and optimization of fully integrated cancer imaging, monitoring, and therapy systems; the validation of integrated image-guided intervention (IGI) systems through clinical evaluations; the development of multiple prototype integrated IGI systems as required for multisite clinical evaluations; and partnerships among small business, large business, and academic clinical centers, as well as small business joint ventures, in order to reach the research goals. Mechanism of Support. This FOA will use the Small Business Innovation Research (SBIR) program (R43/R44) grant mechanism(s) for Phase I, Phase II, and Fast-Track applications and runs in parallel with an FOA of identical scientific intent, PA-07-041, that solicits applications under the Small Business Technology Transfer (STTR) program (R41/R42) grant mechanisms. Funds Available and Anticipated Number of Awards. The SF424 (R and R) SBIR/STTR Application Guide indicates the statutory guidelines of funding support and project duration periods for SBIR Phase I and Phase II awards. For this funding opportunity, budgets up to $150,000 total costs per year and up to 2 years for Phase I may be requested, and a maximum of 3 years of support at budgets of up to $1,000,000 total costs per year may be requested for Phase II research that includes clinical evaluation. However, Phase II activities that do not include clinical evaluation are limited to a maximum budget of $750,000 total cost per year.

rolling
Education

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Image-Guided Cancer Interventions (STTR [R41/R42])

open

National Institutes of Health

Purpose. This Funding Opportunity Announcement (FOA) supports the development and clinical validation of systems for image-guided interventions (IGIs) for cancer. Specifically, the goals of this program are to provide support for: the development and optimization of fully integrated cancer imaging, monitoring, and therapy systems; the validation of integrated IGI systems through clinical evaluations; the development of multiple prototype integrated IGI systems as required for multisite clinical evaluations; and partnerships among small business, large business, and academic clinical centers, as well as small business joint ventures, in order to reach the research goals. Mechanism of Support. This FOA will use the Small Business Technology Transfer (STTR) program (R41/R42) grant mechanism(s) for Phase I, Phase II, and Fast-Track applications and runs in parallel with an FOA of identical scientific intent, PA-07-042, that solicits applications under the Small Business Innovation Research (SBIR) program (R43/R44) grant mechanisms. Funds Available and Anticipated Number of Awards. The SF424 (R and R) SBIR/STTR Application Guide indicates the statutory guidelines of funding support and project duration periods for STTR Phase I and Phase II awards. For this funding opportunity, budgets up to $150,000 total costs per year and up to 2 years for Phase I may be requested, and a maximum of 3 years of support at budgets of up to $1,000,000 total costs per year may be requested for Phase II research that includes clinical evaluation. However, Phase II activities that do not include clinical evaluation are limited to a maximum budget of $750,000 total cost per year.

rolling
Education

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Innovative Therapies and Clinical Studies for Screenable Disorders (R01)

open

National Institutes of Health

Purpose. This Funding Opportunity Announcement (FOA) issued by the National Institute of Child Health and Human Development (NICHD), the National Institute on Deafness and Other Communication Disorders (NIDCD), and the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), solicit applications for research relevant to the basic understanding and development of therapeutic interventions for currently screened conditions and high priority genetic conditions for which screening could be possible in the near future. In this FOA, a high priority condition is a condition for which the development of an efficacious therapy would make the condition amenable to newborn screening. Mechanism of Support. This FOA will use the NIH Research Project Grant (R01) award mechanism and runs in parallel with two FOAs of identical scientific scope, PAR-06-341 and PAR-06-342, that solicit applications under the Small Research Grant (R03) and the Exploratory/Developmental Research Grant (R21) award mechanisms, respectively. Funds Available and Anticipated Number of Awards. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. The total amount awarded and the number of awards will depend upon the numbers, quality, duration, and costs of the applications received. Eligible Institutions/Organizations. Public/State Controlled Institution of Higher Education; Private Institution of Higher Education; Nonprofit with 501(c)(3) IRS Status (Other than Institution of Higher Education); Nonprofit without 501(c)(3) IRS Status (Other than Institution of Higher Education); Small Business; For-Profit Organization (Other than Small Business); State and Local Governments; U.S. Territory or Possession; Indian/Native American Tribal Government (Federally Recognized); Indian/Native American Tribal Government (Other than Federally Recognized); Indian/Native American Tribally Designated Organization; Non-domestic (non-U.S.) Entity (Foreign Organization); Hispanic-serving Institution; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Alaska Native and Native Hawaiian Serving Institutions; Regional Organization; Others: Eligible agencies of the Federal government; Faith-based or community based organizations.

rolling
Healthhealthcare

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Limited Competition: NIH Research Evaluation and Commercialization Hubs (REACH) (SB0 Clinical Trial Optional)

upcoming

National Institutes of Health

The National Institutes of Health (NIH), including all of its Institutes and Centers, plans to publish a Notice of Funding Opportunity inviting eligible colleges, universities, and nonprofit organizations to apply for the NIH Research Evaluation and Commercialization Hub (REACH) program. The REACH program helps move promising biomedical discoveries from academic research into real-world products that can improve patient care and public health. Through this opportunity, NIH plans to fund five new academic entrepreneurship hubs. These hubs will support researchers by providing early-stage funding, technical and business resources, and mentorship in product development and commercialization. The hubs will focus on high-priority technologies that align with NIH's mission. Together, the funded hubs will form a technology development consortium that will help: Identify the most promising academic biomedical technologies; Fund early product-development work, such as feasibility studies, prototypes, and proof-of-concept studies; Provide access to expertise in science, regulation, reimbursement, business, law, and project management; and Offer entrepreneurship training and hands-on commercialization experience. Public-private partnerships and non-federal matching funding will be important to the program's success. The five awardees will build on lessons learned from previous REACH hubs and support the goals of the Phase 0 Proof of Concept Partnership pilot program, as authorized by the 2011 SBIR/STTR Reauthorization Act (P.L. 112-81 Section 5127) and extended through fiscal year 2031 under the Small Business Innovation and Economic Security Act (P.L. 119-83). The REACH program also supports federal research and development priorities, including preparing the 21st-century workforce, moving technologies from the lab to the marketplace, strengthening partnerships among government, industry, and academia, and addressing local health needs, particularly in medically underserved and/or rural areas.This is a Forecast for a Limited Competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.

2026-11-10
Healthhealthcare

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