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Florida Department of Agriculture and Consumer Services

Grants supporting Florida agricultural development, rural economic diversification, agritourism, and community food systems including the Florida Agricultural Promotion Campaign.

Federation of Southern Cooperatives

Cooperative development and technical assistance for rural Black farmers

Economic Development Administration

EDA provides strategic investments that foster job creation and attract private investment to support development in economically distressed areas of the United States. Under this FFO, EDA solicits applications from both rural and urban areas to provide investments that support construction, non-construction, technical assistance, and revolving loan fund projects under EDA s Public Works and Economic Adjustment Assistance programs. Grants made under these programs are designed to leverage existing regional assets to support the implementation of economic development strategies that advance new ideas and creative approaches to advance economic prosperity in distressed communities.

Economic Development Administration

Under this FFO, EDA solicits applications from applicants in rural and urban areas to provide investments that support construction, non-construction, technical assistance, and revolving loan fund projects under EDA s Public Works and EAA programs. Grants and cooperative agreements made under these programs are designed to leverage existing regional assets and support the implementation of economic development strategies that advance new ideas and creative approaches to advance economic prosperity in distressed communities. EDA provides strategic investments on a competitive- merit-basis to support economic development, foster job creation, and attract private investment in economically distressed areas of the United States.

Economic Development Administration

Under this FFO, EDA solicits applications from applicants in rural and urban areas to provide investments that support construction, non-construction, technical assistance, and revolving loan fund projects under EDA s Public Works and EAA programs. Grants and cooperative agreements made under these programs are designed to leverage existing regional assets and support the implementation of economic development strategies that advance new ideas and creative approaches to advance economic prosperity in distressed communities. EDA provides strategic investments on a competitive- merit-basis to support economic development, foster job creation, and attract private investment in economically distressed areas of the United States.

Department of Housing and Urban Development

Purpose: The Rural Capacity Building program enhances the capacity and ability of rural housing development organizations, Community Development Corporations (CDCs), Community Housing Development Organizations (CHDOs), rural local governments, and Indian tribes (eligible beneficiaries) to carry out affordable housing and community development activities in rural areas for the benefit of low- and moderate-income families and persons. The Rural Capacity Building program achieves this by funding National Organizations with expertise in rural housing and rural community development who work directly to build the capacity of eligible beneficiaries.Eligible Program Activities. RCB program funds are limited to activities that strengthen the organizational infrastructure, management, and governance capabilities of eligible beneficiaries serving rural areas to effectively increase the capacity of the eligible beneficiaries to carry out community development and affordable housing activities that benefit low-income or low- and moderate-income families and persons in rural areas.Training, education, and support. This may include, but is not limited to, building the capacity of eligible beneficiaries to:Conduct organizational assessments;Engage in strategic planning and Board development;Access and implement technological improvements;Engage with rural community stakeholders;Evaluate performance of current and planned rural community efforts;Plan for the use of available rural resources in a comprehensive and holistic manner;Participate in HUD planning efforts to ensure rural participation and the assessment of rural area needs; andFoster regional planning efforts by connecting local, rural community plans with neighboring communities.Financial assistance.Such other activities as may be determined by the grantees in consultation with the Secretary or his or her designee.

Department of Housing and Urban Development

FY 2025 Rural Capacity Building for Community Development and Affordable Housing Grants (RCB)

National Park Service

The goal of the Paul Bruhn Historic Revitalization Subgrants Program is to fund subgrant programs that support the rehabilitation of historic properties to foster economic development in rural communities. These subgrant programs, managed by States, Tribes, Certified Local Governments, special district governments, and non-profits will select, fund, and manage preservation projects for historic properties to include architectural/engineering services and physical preservation.

National Park Service

The goal of the Paul Bruhn Historic Revitalization Subgrants Program is to fund subgrant programs that support the rehabilitation of historic properties to foster economic development in rural communities. These subgrant programs, managed by States, Tribes, Certified Local Governments, special district governments, and non-profits will select, fund, and manage preservation projects for historic properties to include architectural/engineering services and physical preservation.

Community Oriented Policing Services

The Office of Community Oriented Policing Services (COPS) is the component of the U.S. Department of Justice responsible for advancing the practice of community policing and the Administration s priority of Making America Safe Again by supporting the nation s state, local, territorial and Tribal law enforcement agencies through information and grant resources. This is a notice of funding opportunity (NOFO) for the FY26 Law Enforcement Mental Health and Wellness Act (LEMHWA) Program. The mental health and wellness of law enforcement officers and their families is a priority of the Administration. Through the LEMHWA program, the Department of Justice supports this priority by providing funding directly to state, local, tribal, and territorial (SLTT) law enforcement agencies to implement new or enhance existing programs that offer training and services to support officers emotional and mental health including, counseling programs, peer mentoring, suicide prevention, stress reduction, and police officer family services. As community policing is common sense policing, throughout the FY26 LEMHWA program NOFO materials, the terms community policing and common sense policing are used interchangeably, unless otherwise specified. The COPS Office seeks to increase the delivery of and access to mental health and wellness services through this NOFO in the following three funding categories: Category 1: FY26 Start-up LEMHWA Implementation Projects The purpose of this program is to provide funding to law enforcement agencies that do not have established law-enforcement specific mental health and wellness programming. These funds will serve as start-up funding to support the development of new mental health and wellness services and programming for employees of law enforcement agencies and their families. This program also serves to increase grant funding accessibility for small and understaffed departments, especially those in rural communities, to implement mental health and wellness programs. Implementation of peer support, training, family resources, suicide prevention, stress reduction, clinical support, and other promising practices for wellness programs are highly encouraged. Agencies that currently offer rudimentary or limited wellness services and are seeking to develop a comprehensive wellness program for their department are encouraged to apply. Category 2: FY26 Enhanced LEMHWA Implementation Projects The purpose of this program is to provide funding to law enforcement agencies who have current wellness programs in place and are seeking to enhance or expand upon those existing wellness programs. Category 3: FY26 LEMHWA Community of Practice Initiative The purpose of this initiative is to provide support to current and future LEMHWA grantees, that include peer support and technical assistance through the development and facilitation of an innovative forum where grantees can learn from their peers and share promising practices.

Department of Housing and Urban Development

As President Trump said in his Executive Order on Removing Regulatory Barriers to Affordable Home Construction (March 13, 2026), The American dream of homeownership depends on a dynamic housing market in which a varied inventory of new homes is built and renovated each year. Layers of unnecessary regulatory barriers, slow permitting processes, and onerous mandates at all levels of government have delayed construction, restricted development, and driven up the costs of new housing. These constraints have made housing less affordable for many Americans.It is the policy of my Administration to reduce regulatory barriers to building homes and to steward taxpayer dollars in a manner that promotes housing affordability.HUD's PRO Housing program rewards communities that have taken steps to remove regulatory barriers to building and preserving homes by providing funding to further expand affordable housing, particularly homeownership opportunities and housing located in Opportunity Zones and rural communities.HUD is issuing this Fiscal Year 2026 (FY26) PRO Housing NOFO under the authority of the Consolidated Appropriations Act, 2026, which provided $50 million for competitive grant funding for state and local governments, metropolitan planning organizations (MPOs), and multijurisdictional entities. The Appropriations Act requires HUD to award grants using the Community Development Block Grant (CDBG) framework. As with all CDBG assistance, the priority is to serve low- and moderate-income people and households. HUD shall select applicants that demonstrate: (1) progress and a commitment to eliminating local barriers to facilitate the increase in affordable housing production and preservation, through enactment or implementation of less restrictive zoning, land use, or permitting laws and regulations; (2) an acute need for housing affordable to households with incomes below 100 percent of the area median income; and (3) a commitment to create new homeownership units before the expiration of the funding performance period.Applicants and grantees are reminded of the President's Executive Orders on Ending Illegal Discrimination and Restoring Merit-Based Opportunity (January 221, 2025) and Ending Radical and Wasteful Government DEI Programs and Preferences (January 20, 2025) and their applicability to PRO Housing funding. PRO Housing funding may not be used to fund "illegal and immoral discrimination programs, going by the name 'diversity, equity, and inclusion.'"In addition to thoroughly reviewing this NOFO, applicants are strongly encouraged to monitor HUD's PRO Housing website for information about general updates, Frequently Asked Questions, and PRO Housing webinars.HUD has four goals for this competition:Decrease the cost and increase the supply of affordable housing, especially in Opportunity Zones and rural communities.Remove barriers to affordable housing, removal of which will lead to constructing or rehabilitating more units, reducing time to produce units, and unlocking land that can be used for affordable housing units.Reward jurisdictions that have enacted laws and regulations that will lead to more affordable housing production and preservation.Increase opportunities for affordable homeownership by reducing administrative and structural barriers.

Department of Housing and Urban Development

As President Trump said in his Executive Order on Removing Regulatory Barriers to Affordable Home Construction (March 13, 2026), The American dream of homeownership depends on a dynamic housing market in which a varied inventory of new homes is built and renovated each year. Layers of unnecessary regulatory barriers, slow permitting processes, and onerous mandates at all levels of government have delayed construction, restricted development, and driven up the costs of new housing. These constraints have made housing less affordable for many Americans.It is the policy of my Administration to reduce regulatory barriers to building homes and to steward taxpayer dollars in a manner that promotes housing affordability.HUD's PRO Housing program rewards communities that have taken steps to remove regulatory barriers to building and preserving homes by providing funding to further expand affordable housing, particularly homeownership opportunities and housing located in Opportunity Zones and rural communities.HUD is issuing this Fiscal Year 2026 (FY26) PRO Housing NOFO under the authority of the Consolidated Appropriations Act, 2026, which provided $50 million for competitive grant funding for state and local governments, metropolitan planning organizations (MPOs), and multijurisdictional entities. The Appropriations Act requires HUD to award grants using the Community Development Block Grant (CDBG) framework. As with all CDBG assistance, the priority is to serve low- and moderate-income people and households. HUD shall select applicants that demonstrate: (1) progress and a commitment to eliminating local barriers to facilitate the increase in affordable housing production and preservation, through enactment or implementation of less restrictive zoning, land use, or permitting laws and regulations; (2) an acute need for housing affordable to households with incomes below 100 percent of the area median income; and (3) a commitment to create new homeownership units before the expiration of the funding performance period.Applicants and grantees are reminded of the President's Executive Orders on Ending Illegal Discrimination and Restoring Merit-Based Opportunity (January 221, 2025) and Ending Radical and Wasteful Government DEI Programs and Preferences (January 20, 2025) and their applicability to PRO Housing funding. PRO Housing funding may not be used to fund "illegal and immoral discrimination programs, going by the name 'diversity, equity, and inclusion.'"In addition to thoroughly reviewing this NOFO, applicants are strongly encouraged to monitor HUD's PRO Housing website for information about general updates, Frequently Asked Questions, and PRO Housing webinars.HUD has four goals for this competition:Decrease the cost and increase the supply of affordable housing, especially in Opportunity Zones and rural communities.Remove barriers to affordable housing, removal of which will lead to constructing or rehabilitating more units, reducing time to produce units, and unlocking land that can be used for affordable housing units.Reward jurisdictions that have enacted laws and regulations that will lead to more affordable housing production and preservation.Increase opportunities for affordable homeownership by reducing administrative and structural barriers.

Georgia Department of Agriculture

Georgia agriculture department grants support rural development, agribusiness, and local food system initiatives across Georgia, funding projects that strengthen farm viability and rural economic competitiveness.

Housing Assistance Council

Pre-development loans for rural affordable housing projects

Housing Assistance Council

Capacity building for rural housing and community development organizations

NIDA - National Institute on Drug Abuse

PROJECT SUMMARY Alcohol, tobacco, and other drug use (ATOD), sexual health risks, and postpartum depression (PPD) are common and significant interrelated factors that are associated with poor health consequences for pregnant women and their infants, especially among rural, under-resourced communities. Thus, there is an urgent need to simultaneously address these health risks together during this vulnerable time. While pregnancy has been recognized as a window of opportunity in which to intervene, there are no empirically supported interventions tailored to specifically address these growing public health concerns together in rural women during pregnancy and postpartum. The objective of this R01 study is to fill this critical gap by building upon our promising R21/R01 findings by (1) partnering with a community advisory board to adapt and optimize the existing Health Check-up for Expectant Moms (HCEM) web-delivered Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) program to include the interconnected risks of tobacco use and postpartum depression (PPD) among rural pregnant women (herein referred to as HCEM+), and (2) testing the efficacy of the HCEM+ in reducing ADOT, STI, and PPD risk more than a time and information matched control condition in rural pregnant women seeking prenatal care. This research addresses cross-cutting priorities in line with NIDA’s Strategic Plan to advance science on drug use: (1) prioritizing research to combat stigma and improve engagement in treatment, (2) developing and enhancing culturally responsive and tailored interventions, and (3) delivering care for substance use and co-occurring health conditions such as STIs and mental illness. We propose a two-group, randomized controlled trial in which a sample of 250 high-risk rural pregnant women attending prenatal care will be assigned to either (a) a web-delivered, two-session SBIRT/P plus two booster sessions consistent with motivational interviewing and informed by the Information-Motivation-Behavior (IMB) model, the HCEM+, or (b) a web-delivered control condition. Web-delivered follow-up assessments will occur at 8 and 24 weeks antenatally, and at 6 weeks postpartum, extending outcomes to the postpartum period. Specific Aim 1 is to test the hypothesis that HCEM+, compared to an attention, time and information matched control condition, will reduce unprotected sexual occasions and ADOT use among at-risk pregnant women during pregnancy at 2 and 6-months follow-up, and will increase treatment engagement. Specific Aim 2 is to test the hypothesis that HCEM+, compared to control, will reduce STIs and ADOT use at 6 weeks postpartum and will result in better birth outcomes and reduced rates of PPD. An economic evaluation of the costs of the HCEM+ will occur to guide future implementation and dissemination. Results of this program of research are expected to inform the development of a practical, cost-effective, high-reaching web-delivered SBIRT/P program tailored to reach high-risk rural and under-resourced women with extended impact to the postpartum period.

NIA - National Institute on Aging

PROJECT SUMMARY Background: Rural older Americans are at heightened risk for developing and dying from critical illness. Yet despite having 22% of America’s older adults, rural communities only have 1% of America’s intensive care unit (ICU) beds. As such, rural ICUs are dependent on the network of hospitals around them to help care for their critically ill—making rural ICUs particularly vulnerable to external disruptions. Extreme weather events disrupt this network of ICU care and place older adults at risk of increased hospitalizations and mortality. Therefore, there is an urgent need to understand the long-term effects of extreme weather events on rural ICUs and the older adults they serve. Project Methods: Aim 1: The effect of extreme weather on one-year mortality among critically ill, rural older adults. Survival analyses will evaluate differences in one-year mortality after critical illness among older adults based on exposure to disaster and rurality using Medicare claims. Aim 2: Associations between rural hospital networks, interhospital transfers, and mortality among critically ill, rural older adults affected by disaster. Network analyses will characterize rural hospitals based on interhospital transfer networks. Then, relationships between rural hospital networks and 30-day mortality will be examined among critically ill, rural older adults affected by disaster. Aim 3: Healthcare readiness during disaster events when caring for critically ill, rural older adults. Semi-structured interviews with 45 staff members from four hospitals who cared for critically ill, rural older adults during disasters will create a framework that defines essential elements of healthcare readiness. Unique Aspects of this Proposal: This application tackles a pressing problem—the impact of extreme weather on vulnerable critically ill, older adults in rural communities—by uniting a physician-researcher with expertise in rural ICU care delivery with a nurse-researcher with expertise in the impact of disasters on the health and well-being of older adults. With an experienced team, expert National Advisory Board, and blend of quantitative and qualitative analyses, the PIs are uniquely equipped to address this urgent challenge. Anticipated Impact: Extreme weather events pose a major threat to critically ill older adults who receive healthcare in rural communities. This study will lead to interventions across individual, health system, and community levels that strengthen systems of ICU care and recovery and mitigate adverse health consequences for vulnerable, rural older adults.

NIAID - National Institute of Allergy and Infectious Diseases

Project Summary HIV drug resistance represents a growing and underappreciated threat to the U.S. HIV response. Although more than 1.2 million people are living with HIV in the U.S., only about 60% achieve durable viral suppression, and resistance is a major contributor to treatment failure and regimen switching. Current resistance testing relies on centralized, PCR and sequencing-based platforms that are expensive, slow, and available only at specialty laboratories, requiring multiple clinic visits and highly trained personnel. As a result, same- day, resistance-informed treatment decisions are rarely possible, even in major U.S. cities, and are essentially inaccessible in rural areas, mobile care units, and safety-net clinics serving areas where the epidemic is increasingly concentrated. These gaps most severely affect communities already carrying the highest burden of HIV incidence and treatment failure in the U.S. Without affordable, accessible, point-of-care (POC) resistance testing, the durability of ART and the success of the national Ending the HIV Epidemic initiative are at risk. Our project aims to develop HIV-CRISP to addresses this critical gap by developing a cost-effective, same- visit “test-and-switch” POC device that integrates CRISPR-based nucleic acid detection with a bioinspired microfluidic chip (CamoChip). This fully automated platform enables simultaneous detection of HIV viral load and drug resistance to four major ART classes (NRTIs, NNRTIs, INSTIs, and PIs) during a single clinic visit. By empowering providers to make immediate, resistance-informed treatment decisions, HIV-CRISP reduces delays in therapy initiation or modification and minimizes the risk of treatment failure. The project is structured around three specific aims: Specific Aim 1: optimize a PAMmer-assisted CRISPR system for accurate detection and profiling of HIV drug resistance mutations; Specific Aim 2: enhance CamoChip readout technology for rapid, multiplex POC testing; and Specific Aim 3: integrate these components into a user-informed POC device and validate its performance against standard methods with clinical samples. Each aim not only drives independent scientific advances but also converges on the development of a transformative POC diagnostic. HIV-CRISP represents an innovation in HIV diagnostics with broad public health significance. This platform supports wide access to high-quality HIV care in under-resourced settings across the U.S. and globally, while also providing a foundation adaptable to other infectious diseases and health conditions.

Idaho Department of Commerce

The Gem Grant program supports economic development in rural Idaho communities with populations under 10,000, funding infrastructure improvements, public facilities, and projects that support business growth and job creation.

Idaho Department of Commerce

Idaho Commerce provides grants to rural Idaho communities for economic development planning, community infrastructure, downtown revitalization, and projects that improve quality of life and attract business investment.

FIC - John E. Fogarty International Center for Advanced Study in the Health Sciences

Alcohol use is a major contributor to injury burden worldwide and remains an important public health challenge in the United States (US), particularly in underserved regions with limited access to trauma and behavioral health services. Cameroon, like other Sub-Saharan African countries, is disproportionately affected by alcohol- related injuries (ARIs), with higher injury burden and alcohol consumption than neighboring countries. Similar barriers to integrating alcohol use disorder (AUD) interventions into trauma care also persist in low-resource trauma settings in the US, where workforce shortages and constrained trauma systems limit delivery of evidence-based AUD care. As involvement in an ARI significantly increases the risk of subsequent ARIs, failure to address AUD in injured patients currently represents a missed opportunity for both AUD treatment and injury prevention. The Screening, Brief Intervention, and Referral to Treatment (SBIRT) model is an evidence-based intervention used in emergency departments (EDs) in high-income countries, including the US, to identify and address AUD. However, implementation of SBIRT remains inconsistent in US resource- limited trauma settings due to staffing, workflow, and infrastructure barriers. Cameroon provides a unique opportunity to evaluate scalable SBIRT implementation strategies in a severely resource-constrained trauma system where AUD services are limited but where strong trauma research infrastructure and pilot data already exist. The long-term goal of this project is to reduce the burden of ARIs by leveraging research infrastructure in Cameroon to develop scalable evidence-based models for integrating AUD interventions into trauma systems. The overall objective is to evaluate the feasibility and effectiveness of a Cameroon-adapted SBIRT intervention in the ED setting. We hypothesize that the adapted SBIRT intervention will significantly reduce hazardous alcohol use among trauma patients. To achieve this objective, the study will pursue three aims: 1) train ED healthcare providers on a Cameroon-adapted SBIRT program; 2) evaluate feasibility, acceptability, and fidelity of SBIRT implementation in the Cameroonian ED context; and 3) evaluate effectiveness of SBIRT implementation in reducing hazardous drinking behaviors and PEth biomarker levels. This study will leverage implementation science methods to evaluate real-world implementation and scalability of SBIRT in a resource- constrained trauma system. Findings from this work may inform scalable implementation approaches for underserved trauma settings in the US, including rural hospitals and trauma deserts with limited access to integrated AUD care, while also supporting broader implementation across low-resource settings globally.

Infosys Foundation

100M+ USD/yr supporting education, healthcare, rural development, and arts in India.

U.S. National Science Foundation

Infrastructure systems comprise complex connections between physical components, organizational structures and operational methods that support the needs of people and communities at the local, regional, national, and global scales. Such systems form the backbone of society, providing essential services as well as ensuring public health and welfare, economic prosperity and national security, and are expected to function under all operational conditions. Meanwhile, infrastructure systems are capital intensive and vulnerable to disruptions from extreme events, including natural disasters, social crises, and malicious attacks. Disruptions in one system can have cascading impacts on others in space and over time. Moreover, short- versus long-term trade-offs, unintended consequences, and maladaptation are not often accounted for. How systems function at the extreme, which can be due to disruptors from the introduction of innovation, the convergence of technologies, sudden changes to their utilization and access, dramatic changes in operating environments, and changes to demand during crises are of particular interest. To ensure the efficiency, sustainability, resilience, and fair use of infrastructure systems, it is important to continuously improve and optimize their design, operations, system monitoring and performance assessment in dynamic, uncertain and sometime unknown environments. While functioning at extremes is of interest, the program also supports infrastructure systems research under the full range of operating conditions, across a variety of hazards, and in urban, suburban, and rural communities. The program particularly encourages interdisciplinary and multidisciplinary exploration that will open new research frontiers and significantly expand and transform relevant research communities. The program welcomes research that addresses novel system integration, user-inspired system and service design, data analytics, and socio-technical studies focused on engineering and system innovation during normal and extreme conditions. The program also values innovative research efforts focused on collecting, standardizing, and sharing large-scale databases of real-world infrastructure systems and people-infrastructure interactions during normal and extreme operating conditions, which can be instrumental in providing benchmarks for model verification and validation and for advancing future research innovation in ISP. The ISP program supports research on lifeline systems and communities that contributes to the National Science Foundation s role in the National Earthquake Hazards Reduction Program (NEHRP) and the National Windstorm Impact Reduction Program (NWIRP). Principal Investigators are encouraged to leverage NSF s investments in the Natural Hazards Engineering Research Infrastructure (NHERI) experimental, computational modeling and simulation, and data resources (https://www.designsafe-ci.org/) in their research to accelerate advances needed for reducing the impacts of natural hazards on infrastructures and people. While physics-based subject-matter knowledge may be crucial in many research efforts, the program does not support research whose primary methodological contribution focuses on individual infrastructure components without a systems research perspective whose primary methodological focus is on geotechnical and structural engineering, material sciences, architectural engineering, wireless communication and sensor technology, human factors, and/or hydrologic or environmental engineering. Proposers are actively encouraged to email a one-page project summary to the ISP Program Officers before submitting a full proposal for guidance on whether the proposed research topic falls within the scope of the ISP program; this guidance should especially be requested for multi-disciplinary research proposals, and proposals for which research and/or development on the subject infrastructure(s) are also supported by other federal and/or state agencies.

U.S. National Science Foundation

Infrastructure systems comprise complex connections between physical components, organizational structures and operational methods that support the needs of people and communities at the local, regional, national, and global scales. Such systems form the backbone of society, providing essential services as well as ensuring public health and welfare, economic prosperity and national security, and are expected to function under all operational conditions. Meanwhile, infrastructure systems are capital intensive and vulnerable to disruptions from extreme events, including natural disasters, social crises, and malicious attacks. Disruptions in one system can have cascading impacts on others in space and over time. Moreover, short- versus long-term trade-offs, unintended consequences, and maladaptation are not often accounted for. How systems function at the “extreme,” which can be due to disruptors from the introduction of innovation, the convergence of technologies, sudden changes to their utilization and access, dramatic changes in operating environments, and changes to demand during crises are of particular interest. To ensure the efficiency, sustainability, resilience, and fair use of infrastructure systems, it is important to continuously improve and optimize their design, operations, system monitoring and performance assessment in dynamic, uncertain and sometime unknown environments. While functioning at extremes is of interest, the program also supports infrastructure systems research under the full range of operating conditions, across a variety of hazards, and in urban, suburban, and rural communities. The program particularly encourages interdisciplinary and multidisciplinary exploration that will open new research frontiers and significantly expand and transform relevant research communities. The program welcomes research that addresses novel system integration, user-inspired system and service design, data analytics, and socio-technical studies focused on engineering and system innovation during normal and extreme conditions. The program also values innovative research efforts focused on collecting, standardizing, and sharing large-scale databases of real-world infrastructure systems and people-infrastructure interactions during normal and extreme operating conditions, which can be instrumental in providing benchmarks for model verification and validation and for advancing future research innovation in ISP. The ISP program supports research on lifeline systems and communities that contributes to the National Science Foundation’s role in the National Earthquake Hazards Reduction Program (NEHRP) and the National Windstorm Impact Reduction Program (NWIRP). Principal Investigators are encouraged to leverage NSF’s investments in the Natural Hazards Engineering Research Infrastructure (NHERI) experimental, computational modeling and simulation, and data resources (https://www.designsafe-ci.org/) in their research to accelerate advances needed for reducing the impacts of natural hazards on infrastructures and people. While physics-based subject-matter knowledge may be crucial in many research efforts, the program does not support research whose primary methodological contribution focuses on individual infrastructure components without a systems research perspective whose primary methodological focus is on geotechnical and structural engineering, material sciences, architectural engineering, wireless communication and sensor technology, human factors, and/or hydrologic or environmental engineering. Proposers are actively encouraged to email a one-page project summary to the ISP Program Officers before submitting a full proposal for guidance on whether the proposed research topic falls within the scope of the ISP program; this guidance should especially be requested for multi-disciplinary research proposals, and proposals for which research and/or development on the subject infrastructure(s) are also supported by other federal and/or state agencies.