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View full policySingle Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2
About This Grant
<p>NIDA seeks to further advance its mission in the area of single cell biology. Since 2020, the NIDA-funded Single Cell Opioid Responses in the Context of HIV (SCORCH) consortium has generated single-nucleus datasets from human and animal postmortem brain tissue under conditions of HIV infection, antiretroviral therapy (ART), and/or substance exposure (e.g. opioids, cocaine, methamphetamine, and cannabinoids). Building on this Phase 1 foundation, NIDA will encourage research addressing critical questions on Substance Use Disorder (SUD) and interactions with HIV disease progression at the subcellular, cellular, or circuit levels in the Central Nervous System (CNS). Many new cutting-edge single cell approaches (e.g. interrogation of RNA splicing, non-coding RNAs, epigenomic or proteomic features, subcellular or synaptic localization and function, spatial interactions, cell-cell communication, or cellular connectivity) now enable novel hypothesis-generating studies. Along with data mining studies to identify candidate mechanisms or targets contributing to HIV/SUD interactions and hypothesis-driven studies to assess functional significance, we expect SCORCH Phase 2 to significantly advance our mechanistic understanding of SUDs and HIV in the CNS and identify targets for novel therapies. Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284</p>
Grant Summary
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 is a National Institutes of Health grant providing up to $1M for university, municipality, nonprofit. Applications are due 2027-06-08 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
How to Apply
Up to $1M
2027-06-08
- 1Confirm your organization is eligible for Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2: Frequently Asked Questions
Who is eligible for the Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2?
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 is offered by National Institutes of Health and is generally open to university, municipality, nonprofit, tribal government, small business, school district. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 provide?
Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 provides up to $1M per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 deadline?
Applications for Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2 are due 2027-06-08 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2?
To apply for Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Phase 2, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.