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View full policyHEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network
National Institutes of Health
About This Grant
<p>The National Institute of Neurological Disorders and Stroke, in conjunction with other NIH Institutes and Centers (ICs) as a part of the congressionally mandated <a href="https://heal.nih.gov/">NIH Helping to End Addiction Long Term (HEAL) initiative</a> intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for comprehensive ‘omics and physiology dataset generation using primary human tissue across the pain neuraxis. Applications should focus on large-scale, high-throughput data generation and analysis of human genes, epigenome, transcriptome, proteome, metabolome, and phenotyping of neuronal and non-neuronal cells at the single-cell and tissue levels. This NOFO is intended as a continuation of the NIH HEAL Initiative’s <a href="https://sparc.science/about/consortia/precision">Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network</a>. The goal of this research will be to expand the generation and dissemination of comprehensive datasets using primary pain-associated human tissues, incorporate cutting-edge technologies, enhance coverage across multiple pain conditions, and extend integration and harmonization of multimodal outputs. This NOFO will utilize a milestone-driven, cooperative agreement mechanism, in which awarded centers will work collaboratively as a network to develop best practices, optimize protocols, replicate and cross-validate research findings, and collectively build an integrated knowledgebase, with digital resources for the entire pain research and therapeutics development communities. NIH program staff involvement is expected to coordinate alignment with the broader <a href="https://heal.nih.gov/data/heal-data-ecosystem">HEAL Data Sharing Ecosystem</a> and account for evolving priorities to ensure program objectives are achieved.</p><p>Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful multidisciplinary collaborations and responsive projects. Investigators with expertise and insights into comprehensive ‘omics and physiology dataset generation in primary human tissue are encouraged to consider applying for this NOFO. In addition, applications from collaborating, multidisciplinary teams of neurobiologists, pain biologists, human pain scientists and/or physicians, surgeons, and scientists with expertise in statistics, physics, engineering, and bioinformatics should consider applying to this funding opportunity.</p>
Grant Summary
HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network is a National Institutes of Health grant providing funding that varies by award for small business, tribal government, municipality. Applications are due 2026-10-12 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government, including the NIH Intramural Program;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to Apply
Up to $0K
2026-10-12
- 1Confirm your organization is eligible for HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network: Frequently Asked Questions
Who is eligible for the HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network?
HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network is offered by National Institutes of Health and is generally open to small business, tribal government, municipality, nonprofit, school district, university. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network provide?
HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network deadline?
Applications for HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network are due 2026-10-12 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network?
To apply for HEAL Initiative: Program to Reveal and Evaluate Cells-to-gene Information that Specify Intricacies, Origins and the Nature of (PRECISION) Human Pain Network, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.