NIH AI Restriction
NIH policy NOT-OD-25-132 prohibits the use of AI-generated text in grant applications that is not substantially modified by the applicant. All AI-drafted sections must be thoroughly rewritten in your own words before submission.
View full policyOpportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
About This Grant
The goal of this program is to support collaborative translational research projects aligned with NIH efforts to enhance the translation of basic biological discoveries into clinical applications that improve health. It encourages high quality science demonstrating the potential to result in understanding an important disease process or lead to new therapeutic interventions, diagnostics, or prevention strategies within the research interests and priorities of the participating NIH Institutes/Centers (ICs).Specifically, the program seeks to broaden and strengthen translational research collaborations between basic and clinical researchers both within and outside NIH to accelerate and enhance translational science by promoting partnerships between NIH intramural investigators (e.g., those conducting research within the labs and clinics of the NIH) and extramural investigators (e.g., those conducting research in labs outside the NIH), and by providing support for extramural investigators to take advantage of the unique research opportunities available at the NIH Clinical Center by conducting clinical research projects in collaboration with NIH intramural investigators.
Grant Summary
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) is a National Institutes of Health grant providing up to $500K for nonprofit, municipality, tribal government. Applications are due 2027-03-06 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. This new requirement was effective, May 1, 2025.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.
How to Apply
Up to $500K
2027-03-06
- 1Confirm your organization is eligible for Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
Search & build free — $99 one-time to unlock the export-ready application pack. No subscription.
Don't want to draft it yourself?
We'll draft the complete application against National Institutes of Health's requirements, run a quality review, and email you a submission-ready PDF plus an editable Word doc within 5 business days. Most orders deliver in 24-48 hours. Flat $399, any grant size.
AI Requirement Analysis
Detailed requirements not yet analyzed
Have the NOFO? Paste it below for AI-powered requirement analysis.
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional): Frequently Asked Questions
Who is eligible for the Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)?
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) is offered by National Institutes of Health and is generally open to nonprofit, municipality, tribal government, university, school district, small business. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) provide?
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) provides up to $500K per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) deadline?
Applications for Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional) are due 2027-03-06 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)?
To apply for Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.