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View full policyNIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System
National Institutes of Health
About This Grant
<p>The NIH Blueprint (a consortium of NIH Institutes that support neuroscience research) seeks to advance its mission by supporting the development, optimization, validation, and application of germline and somatic transgenic and gene-editing approaches in experimental systems modeling key features of human brain anatomy, circuitry, cognition, behavior, and lifespan. This initiative will build on the previously supported marmoset gene-editing infrastructure, by integrating New Approach Methodologies (NAMs) with other models, to advance understanding of human brain function and disease, including human-derived NAMs for cross-species comparisons across development. Many mechanisms of complex conditions, such as autism spectrum disorders, schizophrenia, and other behavioral/developmental disorders, cannot yet be captured in NAMs and are therefore high priorities for research investment to accelerate development and validation of human-derived NAMs. Appropriate models should be used and clearly justified as necessary for questions involving neuroanatomy, circuit function, cognition, behavior, or lifespan phenotyping related to human brain disease and function. Grant authorities are as follows: 42 U.S.C 241 and 284.</p>
Grant Summary
NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System is a National Institutes of Health grant providing up to $1.2M for small business, municipality, university. Applications are due 2026-10-12 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to Apply
Up to $1.2M
2026-10-12
- 1Confirm your organization is eligible for NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System: Frequently Asked Questions
Who is eligible for the NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System?
NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System is offered by National Institutes of Health and is generally open to small business, municipality, university, tribal government, nonprofit, school district. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System provide?
NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System provides up to $1.2M per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System deadline?
Applications for NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System are due 2026-10-12 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System?
To apply for NIH Blueprint Initiative: Tools for Germline Gene Editing in the Nervous System, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.