NIOSH Centers of Excellence for Total Worker Health® (U19)
About This Grant
PURPOSE NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation.
PRIORITY AREAS • High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies • Young workers, SMEs • Chronic disease • Mental health, stress • Substance use disorder • Artificial intelligence (AI), digital technologies
This is a multi-component NOFO.
COMPONENT STRUCTURE Percentages indicate maximum share of total budget.
Overall Component (Required) Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.
Administration, Evaluation, and Emerging Issues Core (Required; up to 15%) Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.
Outreach, Dissemination, and Impact Core (Required; up to 15%) Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.
Research Projects (Required; about 60 to 70%) Includes all research activities. Applicants may propose a mix of projects. Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact.
• Small Research Projects (Required; at least one project; up to 3 years) Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies. Priority areas: high-risk occupations, young workers, SMEs. Should show innovation and potential to expand. • Large Research Projects (Required; at least one project; up to 5 years) Multiyear etiologic, mechanistic, intervention, or translational studies. Priority areas: chronic disease, mental health, substance use disorder. Economic evaluation is required. Projects should include strong design and analytic plans. • Pilot/Feasibility Program (Optional; 12–18 months) Short-term studies generating preliminary data or testing AI/digital technology approaches.
Grant Summary
NIOSH Centers of Excellence for Total Worker Health® (U19) is a Centers for Disease Control and Prevention - ERA grant providing $500K to $1.4M for nonprofit, small business, university. This is a forecast: it is not yet open for applications, and the estimated deadline is 2027-02-26. Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.
How to Apply
$500K–$1.4M
Estimated 2027-02-26
- 1Confirm your organization is eligible for NIOSH Centers of Excellence for Total Worker Health® (U19) from Centers for Disease Control and Prevention - ERA, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to Centers for Disease Control and Prevention - ERA before the deadline.
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NIOSH Centers of Excellence for Total Worker Health® (U19): Frequently Asked Questions
Who is eligible for the NIOSH Centers of Excellence for Total Worker Health® (U19)?
NIOSH Centers of Excellence for Total Worker Health® (U19) is offered by Centers for Disease Control and Prevention - ERA. The listing names these applicant types: nonprofit, small business, university, municipality, tribal government, healthcare org, school district. It is open to organizations nationwide unless the funder specifies otherwise. The funder's eligibility section is the authority, so confirm your organization type, location, and the population or project served against it before applying.
How much funding does the NIOSH Centers of Excellence for Total Worker Health® (U19) provide?
NIOSH Centers of Excellence for Total Worker Health® (U19) provides between $500K and $1.4M per award from Centers for Disease Control and Prevention - ERA. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the NIOSH Centers of Excellence for Total Worker Health® (U19) deadline?
NIOSH Centers of Excellence for Total Worker Health® (U19) is a forecast from Centers for Disease Control and Prevention - ERA: it is not yet open for applications. The funder's estimated deadline is 2027-02-26, and forecast dates often change. Confirm the official posting with the funder before you prepare an application.
How do you apply for the NIOSH Centers of Excellence for Total Worker Health® (U19)?
To apply for NIOSH Centers of Excellence for Total Worker Health® (U19), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from Centers for Disease Control and Prevention - ERA.
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