NIOSH Centers of Excellence for Total Worker Health® (U19)
About This Grant
<p><strong>PURPOSE</strong><br>NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. </p><p><strong>PRIORITY AREAS</strong><br>• High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies<br>• Young workers, SMEs <br>• Chronic disease<br>• Mental health, stress<br>• Substance use disorder<br>• Artificial intelligence (AI), digital technologies</p><p>This is a multi-component NOFO.</p><p><strong>COMPONENT STRUCTURE</strong><br>Percentages indicate maximum share of total budget.</p><p><strong>Overall Component (Required)</strong><br>Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.</p><p><strong>Administration, Evaluation, and Emerging Issues Core (Required; up to 15%)</strong><br>Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.</p><p><strong>Outreach, Dissemination, and Impact Core (Required; up to 15%)</strong><br>Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.</p><p><strong>Research Projects (Required; about 60 to 70%)</strong><br>Includes all research activities. Applicants may propose a mix of projects. Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact.</p><ul><li data-list-item-id="ea042ead4bda90f7afca9db4ed6265ccb"><i><strong>Small Research Projects (Required; at least one project; up to 3 years)</strong></i><br>Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies.<br>Priority areas: high-risk occupations, young workers, SMEs.<br>Should show innovation and potential to expand. </li><li data-list-item-id="eab66fe3983b477c58a224d9b02cf204c"><i><strong>Large Research Projects (Required; at least one project; up to 5 years)</strong></i><br>Multiyear etiologic, mechanistic, intervention, or translational studies.<br>Priority areas: chronic disease, mental health, substance use disorder. <br>Economic evaluation is required. Projects should include strong design and analytic plans. </li><li data-list-item-id="ed259d50833d70d74aa5cc6f2b4cd83d6"><i><strong>Pilot/Feasibility Program (Optional; 12–18 months)</strong></i> <br>Short-term studies generating preliminary data or testing AI/digital technology approaches.</li></ul>
Grant Summary
NIOSH Centers of Excellence for Total Worker Health® (U19) is a Centers for Disease Control and Prevention - ERA grant providing $500K to $1.4M for nonprofit, small business, university. Applications are due 2027-02-26 (open). Check eligibility and apply with FindGrants.
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Eligibility
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.
How to Apply
$500K–$1.4M
2027-02-26
- 1Confirm your organization is eligible for NIOSH Centers of Excellence for Total Worker Health® (U19) from Centers for Disease Control and Prevention - ERA, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to Centers for Disease Control and Prevention - ERA before the deadline.
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NIOSH Centers of Excellence for Total Worker Health® (U19): Frequently Asked Questions
Who is eligible for the NIOSH Centers of Excellence for Total Worker Health® (U19)?
NIOSH Centers of Excellence for Total Worker Health® (U19) is offered by Centers for Disease Control and Prevention - ERA and is generally open to nonprofit, small business, university, municipality, tribal government, healthcare org, school district. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the NIOSH Centers of Excellence for Total Worker Health® (U19) provide?
NIOSH Centers of Excellence for Total Worker Health® (U19) provides between $500K and $1.4M per award from Centers for Disease Control and Prevention - ERA. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the NIOSH Centers of Excellence for Total Worker Health® (U19) deadline?
Applications for NIOSH Centers of Excellence for Total Worker Health® (U19) are due 2027-02-26 (open). Because deadlines can change, verify the date with the funder, Centers for Disease Control and Prevention - ERA, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the NIOSH Centers of Excellence for Total Worker Health® (U19)?
To apply for NIOSH Centers of Excellence for Total Worker Health® (U19), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from Centers for Disease Control and Prevention - ERA.