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View full policyImpact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks
National Institutes of Health
About This Grant
<p style="margin-left:0in;">The National Institute of Mental Health (NIMH) intends to publish a notice of funding opportunity (NOFO) to solicit biphasic research applications to evaluate the impact of HIV immunotherapies on central nervous system (CNS) outcomes in people with HIV and to identify mechanisms, benefits, and risks associated with their use in the CNS compartment. The primary goal is to generate evidence that informs whether HIV immunotherapies can safely and effectively target CNS HIV persistence while minimizing neurotoxicity and neuroinflammation. By addressing CNS-specific barriers such as blood brain barrier penetration, compartmentalized viral dynamics, and immune-mediated effects, this NOFO will support the development of strategies that contribute to sustained virologic remission across anatomical compartments and improve long-term neurologic and cognitive outcomes in people with HIV. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise and insights into the impact of HIV immunotherapies on the CNS and viral reservoirs are strongly encouraged to apply to this new NOFO. This NOFO will utilize the R21/R33 activity code.</p>
Grant Summary
Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks is a National Institutes of Health grant providing funding that varies by award for nonprofit, school district, tribal government. Applications are due 2026-10-22 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;
How to Apply
Up to $0K
2026-10-22
- 1Confirm your organization is eligible for Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks: Frequently Asked Questions
Who is eligible for the Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks?
Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks is offered by National Institutes of Health and is generally open to nonprofit, school district, tribal government, municipality, university, small business. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks provide?
Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks deadline?
Applications for Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks are due 2026-10-22 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks?
To apply for Impact of Immunotherapies on CNS Outcomes in People with HIV: Potential Benefits, Challenges and Risks, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.