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Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)

National Institutes of Health

upcoming
OpenLast verified: 2026-06-19

About This Grant

<p>The National Institutes of Health (NIH), including the participating Institutes, Centers and Offices, intends to publish a Notice of Funding Opportunity (NOFO) to invite eligible United States small business concerns (SBCs) to submit Small Business Technology Transfer (STTR) Phase I, and Fast-Track grant applications for the Small Business Transition Grant. Through this NOFO, NIH will support early-career scientists transitioning to entrepreneurship. In addition to funding research and development efforts at the SBC, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI.</p><p>Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop responsive projects, including identification of complementary industry mentors and career development resources. This NOFO will utilize the R41/R42 activity code. United States small businesses that have the research capabilities and technological expertise to contribute to the R&amp;D mission(s) of the NIH awarding components identified in this NOFO are encouraged to begin to consider applying for this new NOFO. This opportunity is available to first-time Principal Investigators, and key personnel must include a mentor with measurable effort committed to the project.&nbsp;</p>

Grant Summary

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) is a National Institutes of Health grant providing funding that varies by award for small business. Applications are due 2027-01-05 (open). Check eligibility and apply with FindGrants.

Focus Areas

health

Eligibility

  • Only United States small business concerns (SBCs), as defined by the Small Business Administration (SBA)(sbir.gov/apply) are eligible to submit applications for this opportunity. Individuals are eligible to serve as the PD/PI if they have never been an independent PD/PI on an NIH or CDC research, or corresponding non-NIH peer-reviewed research grant, and are a U.S. Citizen or Lawful Permanent Resident.
small business

How to Apply

Funding Range

Up to $0K

Deadline

2027-01-05

Complexity
Medium
  1. 1Confirm your organization is eligible for Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) from National Institutes of Health, checking organization type, location, and any population or project requirements.
  2. 2Gather the required documents and information, including your organization details, project plan, and budget figures.
  3. 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
  4. 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional): Frequently Asked Questions

Who is eligible for the Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)?

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) is offered by National Institutes of Health and is generally open to small business. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.

How much funding does the Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) provide?

Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.

When is the Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) deadline?

Applications for Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional) are due 2027-01-05 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.

How do you apply for the Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional)?

To apply for Small Business Transition Grant for New Entrepreneurs (Parent R41/R42 Clinical Trial Optional), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.

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