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View full policyHEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1)
National Institutes of Health
About This Grant
<p>The National Institute of Neurological Disorders and Stroke (NINDS), with other NIH Institutes and Centers (ICs), intends to publish a Notice of Funding Opportunity (NOFO) to investigate the mechanisms of action of therapeutic medical devices with the overall goal of improving clinical outcomes with device-based approaches. Medical devices are essential in managing health conditions, complementing drugs and behavioral interventions, and often offer unique benefits. Despite the commercial availability of numerous medical devices and ongoing development of new technologies, many have shown inconsistent results in preclinical studies, failed translation to humans, and exhibit varied patient outcomes. To overcome these challenges, it is crucial to understand the mechanisms by which medical devices produce a therapeutic effect, to identify physiological markers of neurological conditions, and to assess how device-based therapies influence these markers. Advancing this knowledge will improve device-based interventions, inspire new device designs, and optimize current clinical approaches.</p><p>Applications will be invited from interdisciplinary teams pursuing innovative research on how medical devices produce a therapeutic effect. Applicant teams will likely exhibit expertise in areas such as engineering, biology, pathophysiology, surgery, clinical care, healthcare delivery, biostatistics, software development, computational modeling, artificial intelligence, regulatory science, and clinical trials. This program will accept projects on investigational devices and those already FDA-approved and in clinical use. Applications are expected to include strategies for developing or optimizing therapies that could significantly improve patient care. Supported research may include mechanistic clinical trials, animal studies, and computational modeling or simulation. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.</p>
Grant Summary
HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) is a National Institutes of Health grant providing funding that varies by award for municipality, nonprofit, tribal government. Applications are due 2026-10-30 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to Apply
Up to $0K
2026-10-30
- 1Confirm your organization is eligible for HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1): Frequently Asked Questions
Who is eligible for the HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1)?
HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) is offered by National Institutes of Health and is generally open to municipality, nonprofit, tribal government, small business, university, school district. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) provide?
HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) deadline?
Applications for HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1) are due 2026-10-30 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1)?
To apply for HEAL Initiative: Optimization of Therapeutic Medical Devices through Team Science Mechanistic Research (RM1), confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.