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View full policyNIH Pragmatic Trials Conducted in Health Care Systems
National Institutes of Health
About This Grant
<p>The National Institutes of Health intends to publish a Notice of Funding Opportunity (NOFO), Pragmatic and Implementation Trials Conducted in Health Care Settings</p><p>This funding opportunity will support large-scale pragmatic trials that test intervention effectiveness in routine clinical care and/or implementation trials that evaluate strategies for delivering interventions within health care settings. These trials are intended to directly inform decision-makers (e.g., patients, clinicians, administrators, policymakers, and payers) about the comparative benefits, burdens, and risks of biomedical or behavioral interventions.</p><p>To enhance real-world relevance and generalizability, applicants are encouraged to: <br>1) Select care settings where the target condition is commonly seen (e.g., emergency departments, primary care, public health clinics). <br>2) Include multiple health system types (e.g., academic centers, federally qualified health centers, integrated networks, VA Medical Centers). <br>3) Assess adaptation across systems and regions to ensure intervention effectiveness and implementation feasibility.</p><p>Interventions under study should be embedded in routine care. Trials may integrate one or more interventions with established efficacy into appropriate health care settings or implement system-level changes to improve health outcomes.</p><p>This phased award will use a milestone-driven cooperative agreement mechanism, supporting a planning phase and a phase for full trial execution.</p><p>Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. Investigators with expertise and insights into this area are encouraged to begin to consider applying for this NOFO. </p>
Grant Summary
NIH Pragmatic Trials Conducted in Health Care Systems is a National Institutes of Health grant providing funding that varies by award for small business, school district, tribal government. Applications are due 2027-02-23 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
- Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
How to Apply
Up to $0K
2027-02-23
- 1Confirm your organization is eligible for NIH Pragmatic Trials Conducted in Health Care Systems from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
Don't want to draft it yourself?
We'll draft the complete application against National Institutes of Health's requirements, run a quality review, and email you a submission-ready PDF plus an editable Word doc within 5 business days. Most orders deliver in 24-48 hours. Flat $399, any grant size.
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NIH Pragmatic Trials Conducted in Health Care Systems: Frequently Asked Questions
Who is eligible for the NIH Pragmatic Trials Conducted in Health Care Systems?
NIH Pragmatic Trials Conducted in Health Care Systems is offered by National Institutes of Health and is generally open to small business, school district, tribal government, university, municipality, nonprofit. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the NIH Pragmatic Trials Conducted in Health Care Systems provide?
NIH Pragmatic Trials Conducted in Health Care Systems provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the NIH Pragmatic Trials Conducted in Health Care Systems deadline?
Applications for NIH Pragmatic Trials Conducted in Health Care Systems are due 2027-02-23 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the NIH Pragmatic Trials Conducted in Health Care Systems?
To apply for NIH Pragmatic Trials Conducted in Health Care Systems, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.