NIAID - National Institute of Allergy and Infectious Diseases
The contractor will apply innovative, highly-multiplexed DNA-barcoded antigen assays to comprehensively discover and validate 100,000s of CD4 T cell epitopes across the entire proteome of Mycobacterium Tuberculosis (Mtb) – together with their HLA restrictions, cognate paired TCR α:βs, and corresponding T cell transcriptomes . The Assays will focus on a large panel of HLA proteins that include alleles prevalent in sub-Saharan African populations with high disease burdens but that remain vastly understudied at the epitope level. By comparing cohorts with different disease states across a large two-dimensional space defined by the pathogen genome and host transcriptome, the contractor will identify novel T cell features associated with protection from disease.
Up to $1.0M
2026-09-29
We'll draft the complete application against NIAID - National Institute of Allergy and Infectious Diseases's requirements, run a quality review, and email you a submission-ready PDF plus an editable Word doc within 5 business days. Most orders deliver in 24-48 hours. Flat $399, any grant size.
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