Human Brain Connectome Changes Across the Birth Transition
NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development
About This Grant
Maternal immune activation (MIA) is a significant prenatal insult associated with increased risks of preterm birth and neurodevelopmental disorders in offspring. However, it remains unclear how MIA alters fetal and infant brain development during the critical birth transition period, and how these changes influence later neurodevelopmental outcomes. This study will establish a unique cohort of 90 high-risk pregnancies, leveraging advanced neuroimaging techniques, maternal inflammatory biomarkers, and objective infant behavioral assessments to address two specific aims. Aim 1 will identify brain regions sensitive to MIA and characterize how brain development trajectories are disrupted across the birth transition, focusing on attention, salience, and limbic networks. Aim 2 will investigate whether MIA-related brain disruptions mediate the relationship between maternal inflammation and developmental outcomes. By integrating neural, biochemical, and behavioral data, this work will uncover the mechanisms by which maternal inflammation shapes neurodevelopment, identify early biomarkers of child risk, and inform interventions to improve outcomes for high-risk pregnancies.
Grant Summary
Human Brain Connectome Changes Across the Birth Transition is a NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development grant providing up to $246K for university, nonprofit, healthcare org. Applications are due 2029-01-31 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
How to Apply
Up to $246K
2029-01-31
- 1Confirm your organization is eligible for Human Brain Connectome Changes Across the Birth Transition from NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development before the deadline.
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Human Brain Connectome Changes Across the Birth Transition: Frequently Asked Questions
Who is eligible for the Human Brain Connectome Changes Across the Birth Transition?
Human Brain Connectome Changes Across the Birth Transition is offered by NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Human Brain Connectome Changes Across the Birth Transition provide?
Human Brain Connectome Changes Across the Birth Transition provides up to $246K per award from NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Human Brain Connectome Changes Across the Birth Transition deadline?
Applications for Human Brain Connectome Changes Across the Birth Transition are due 2029-01-31 (open). Because deadlines can change, verify the date with the funder, NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Human Brain Connectome Changes Across the Birth Transition?
To apply for Human Brain Connectome Changes Across the Birth Transition, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NICHD - Eunice Kennedy Shriver National Institute of Child Health and Human Development.