Multisite closed loop DBS for Chronic Pain
NINDS - National Institute of Neurological Disorders and Stroke
About This Grant
PROJECT SUMMARY Chronic pain affects one out of four Americans and is often refractory to any treatment including medications, injections or surgery. Deep brain stimulation (DBS) involves implanting electrodes in key brain regions and holds promise as a new option for therapy, but we currently lack the technology to reliably achieve long-term pain symptom relief. A “one-size-fits-all” approach of continuous, 24/7 brain stimulation has helped patients with some movement disorders, but the key to reducing pain may be the activation of stimulation only when needed. This is called closed loop stimulation which may help to reduce side effects and keep the brain from adapting to stimulation effects. Further, because we know that an individual’s pain experience is processed by many brain regions and no single target works for all patients, DBS that targets these many regions may serve more patients and pain syndromes then just targeting one or two brain regions. We aim to develop a new brain stimulation device platform using personalized brain targets for hard-to-treat chronic pain and to improve technology that will enable the delivery of stimulation only when pain signals in the brain are high. This device platform provides a form factor and ease of use that addresses needs expressed to our team by previous patients and includes necessary technical capabilities that exceed any existing device. We will then test whether personalized stimulation, possible with this device, leads to reliable symptom relief for chronic pain patients over extended periods of time.
Grant Summary
Multisite closed loop DBS for Chronic Pain is a NINDS - National Institute of Neurological Disorders and Stroke grant providing up to $388K for university, nonprofit, healthcare org. Applications are due 2027-04-30 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $388K
2027-04-30
- 1Confirm your organization is eligible for Multisite closed loop DBS for Chronic Pain from NINDS - National Institute of Neurological Disorders and Stroke, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NINDS - National Institute of Neurological Disorders and Stroke before the deadline.
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Multisite closed loop DBS for Chronic Pain: Frequently Asked Questions
Who is eligible for the Multisite closed loop DBS for Chronic Pain?
Multisite closed loop DBS for Chronic Pain is offered by NINDS - National Institute of Neurological Disorders and Stroke and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Multisite closed loop DBS for Chronic Pain provide?
Multisite closed loop DBS for Chronic Pain provides up to $388K per award from NINDS - National Institute of Neurological Disorders and Stroke. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Multisite closed loop DBS for Chronic Pain deadline?
Applications for Multisite closed loop DBS for Chronic Pain are due 2027-04-30 (open). Because deadlines can change, verify the date with the funder, NINDS - National Institute of Neurological Disorders and Stroke, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Multisite closed loop DBS for Chronic Pain?
To apply for Multisite closed loop DBS for Chronic Pain, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NINDS - National Institute of Neurological Disorders and Stroke.