Human Tissue and Organs for Research Resource (HTORR) Supporting Studies on Human Biology, Physiology, and Diseases Across All Body Systems.

About This Grant

Program Director/Principal Investigator (Bell, Thomas, J): Project Summary The overarching objective of this proposal is to continue the development of the Human Tissue and Organs for Research Resource (HTORR) as the foremost, project-driven human tissue research resource for organs and tissues for Principal Investigators (PIs) studying the full extent of human biology and disease states across all body systems. Using a project-driven biospecimen collection approach, HTORR provides a diverse range of biospecimens for these studies, such as whole organs, anatomical structures, fluids, tissues, and cells. HTORR’s innovative 360° feedback model spearheads the advancement of HTORR’s scientific tissue collection framework via providing continuous feedback across three foundational pillars of the program: 1) Scientific Support, 2) Sample Diversity, and 3) Career Development of Principal Investigators (PIs). Our pillars identify, define, and align all key foundational elements in the model along with providing a malleable framework for HTORR to evolve in tandem with the NIH’s high priority scientific needs as well as the emerging experimental methodologies of the research community. Relevance: The Human Tissue and Organs for Research Resource (HTORR) is a comprehensive research resource that enables investigators from multiple research fields and disciplines to utilize human biospecimen derived experimental model systems to rigorously study human organ, tissue and cellular function. HTORR provides state-of-the-art research services to support emerging experimental methodologies and new discoveries in human biology, physiology and disease. OMB No. 0925-0001/0002 (Rev. 03/2020 Approved Through 02/28/2023) Page Continuation Format Page