Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics
About This Grant
Program Summary/Abstract In vivo monitoring of ocular tissues is an essential component of modern vision science research. Common approaches in both the lab and clinic to examine the eye and retina include scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT). Although there is a strong desire for multiple National Eye Institute (NEI)-funded researchers at Washington University to use live imaging techniques to study eye development and degeneration, we have limited capabilities do a lack of any SLO device and an outdated and low quality OCT system. Currently, in vivo imaging is limited to the 2-photon setup of Dr. Williams, which is heavily used and customized making it difficult to meet the demands of our research group through collaborative research. Funds are requested to purchase an UltraEye dual function SLO/OCT microscope with adaptive optics capabilities. The UltraEye will be housed in our department’s newly renovated Visual Function Testing Core facility in the Department of Ophthalmology and Visual Sciences. The core User Group for the new instrument includes 11 faculty members from 3 academic departments who are working with eye development, function and therapeutics development for degeneration. A total of 24 NEI-funded investigators along with the rest of the Washington University research community at large will have access to the SLO/OCT device. Additionally, since the high resolution OCT system is also capable of imaging superficial structures, we will make the system available for reservation via our already existing Facility Online Manager interface that is already established for our Histology, Molecular Biology and Microscopy Cores within the department. The new instrument will 1) Greatly expand in vivo imaging capacity within the Washington University vision research community for experiments with fluorescently labelled animals. 2) Vastly improve the quality of OCT imaging, while also providing high resolution SLO due to the adaptive optics features. 3) Provide new capabilities by powerfully combining SLO and OCT modalities for simultaneous volumetric structural scans. 4) Enable SLO/OCT imaging of non-traditional animal models not supported by current or most other commercial SLO/OCT microscopes. Members of the User Group are engaged in fundamental research into the causes and treatments of retinal ganglion cell degeneration, inherited retinal degeneration, choroidal neovascularization, macular degeneration, uveitis, cataract and corneal dystrophies. The requested instrument will contribute directly and substantively to progress in each of these clinically important areas.
Grant Summary
Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics is a NEI - National Eye Institute grant providing up to $606K for university, nonprofit, healthcare org. Applications are due 2027-07-31 (open). Check eligibility and apply with FindGrants.
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How to Apply
Up to $606K
2027-07-31
- 1Confirm your organization is eligible for Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics from NEI - National Eye Institute, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NEI - National Eye Institute before the deadline.
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Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics: Frequently Asked Questions
Who is eligible for the Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics?
Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics is offered by NEI - National Eye Institute and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics provide?
Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics provides up to $606K per award from NEI - National Eye Institute. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics deadline?
Applications for Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics are due 2027-07-31 (open). Because deadlines can change, verify the date with the funder, NEI - National Eye Institute, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics?
To apply for Dual laser scanning ophthalmoscope and optical coherence tomography scanner with adaptive optics, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NEI - National Eye Institute.