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Scanco nano/microCT system

OD - NIH Office of the Director

open
OpenLast verified: 2026-06-20

About This Grant

Three-dimensional imaging of preclinical and clinical samples to assess the amount, shape and quality of tissues is essential for research studies in musculoskeletal biology, regenerative medicine, and other fields. One established imaging technique for non-destructive assessment of specimens is microcomputed tomography (microCT), which utilizes the differential attenuation of X-rays by various tissues to provide high resolution (0.5 to 10 ìm) 3D images and to facilitate quantification of tissue morphology. MicroCT has been used extensively to characterize bone density and bone morphology, and is an indispensable tool for investigators in a variety of fields, including musculoskeletal biology, developmental biology, fracture healing, organ cross-talk, tissue engineering and regenerative medicine. Advances in imaging technology and contrast agents now allow the use of microCT for characterization of non-mineralized tissues (e.g. cartilage, tendon, & blood vessels), enabling broad usage of this technology. Here we propose to purchase a cabinet, cone beam, ultrahigh-resolution nano/microCT system (ìCT50, Scanco Medical AG). This advanced system acquires images at voxel sizes ranging from 0.5 to 100 ìm and can accommodate sample sizes up to 105 mm in diameter and 120 mm in height. The system is capable of high-throughput imaging due to an integrated automated sample changer, large X-ray detector and powerful computer workstation. The system will benefit a large group of 11 major and 14 other/minor users who have a track record of using microCT to advance their research. These investigators are funded by 23 current NIH research grants from 7 different NIH institutes (NIAMS, NIDDK, NICHD, NIA, NHLBI, NINDS, and NIDCR). The projected usage of the system by NIH-funded investigators is 90% of the accessible use time (AUT, 69% by major users and 21% by other/minor users). The new scanner will be replacing a 17-year-old microCT system that will no longer by supported by the manufacturer due to lack of access to replacement parts (including the x-ray tube, a critical component of the system). Furthermore, the computer workstation required to operate the machine is no longer produced, and any future repairs and service would need to be sourced by a 3rd party vendor. With strong institutional support, this new state-of-the-art nano/microCT system will be embedded in the Translational Imaging and Phenotyping Core, which is part of the NIH P30-funded Center for Musculoskeletal Research. Importantly, the PI has extensive expertise in use of this technology and has successfully operated this imaging core for over a decade. Altogether, the acquisition of a new nano/microCT system via this shared instrumentation grant will have an immediate and sustained benefit to investigators in the greater Boston area and beyond.

Grant Summary

Scanco nano/microCT system is a OD - NIH Office of the Director grant providing up to $425K for university, nonprofit, healthcare org. Applications are due 2027-05-31 (open). Check eligibility and apply with FindGrants.

Focus Areas

health research

Eligibility

universitynonprofithealthcare org

How to Apply

Funding Range

Up to $425K

Deadline

2027-05-31

Complexity
Medium
  1. 1Confirm your organization is eligible for Scanco nano/microCT system from OD - NIH Office of the Director, checking organization type, location, and any population or project requirements.
  2. 2Gather the required documents and information, including your organization details, project plan, and budget figures.
  3. 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
  4. 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to OD - NIH Office of the Director before the deadline.
This record is a past award, contract, or funder profile — useful for research, but not an open grant application. Check the original source for current opportunities from this funder.

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Scanco nano/microCT system: Frequently Asked Questions

Who is eligible for the Scanco nano/microCT system?

Scanco nano/microCT system is offered by OD - NIH Office of the Director and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.

How much funding does the Scanco nano/microCT system provide?

Scanco nano/microCT system provides up to $425K per award from OD - NIH Office of the Director. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.

When is the Scanco nano/microCT system deadline?

Applications for Scanco nano/microCT system are due 2027-05-31 (open). Because deadlines can change, verify the date with the funder, OD - NIH Office of the Director, and give yourself enough time to prepare a complete, competitive application before the close date.

How do you apply for the Scanco nano/microCT system?

To apply for Scanco nano/microCT system, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from OD - NIH Office of the Director.

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