DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS
About This Grant
Project Summary The rise of biocatalysis is transforming synthetic chemistry by enabling highly selective and sustainable transformations. Despite advances, achieving precise stereocontrol in radical-mediated reactions remains a significant frontier. This interdisciplinary research program integrates expertise in organic chemistry, protein engineering, bioinorganic chemistry, and computational modeling to design and evolve enzymatic catalysts for metal-hydride-mediated radical reactions—a versatile yet historically challenging class of asymmetric transformations with broad synthetic utility. These engineered biocatalysts will unlock stereoselective olefin functionalization, enabling diverse carbon-carbon bond-forming and reductive processes without precedent in natural biochemistry. Mechanistic studies will reveal the principles behind these new enzymatic functions, enabling rational design of future biocatalysts. These biocatalysts will advance pharmaceutical synthesis and the construction of complex molecules important to human health.
Grant Summary
DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS is a NIGMS - National Institute of General Medical Sciences grant providing up to $421K for university, nonprofit, healthcare org. Applications are due 2031-02-28 (open). Check eligibility and apply with FindGrants.
Not quite the right fit?
Search 9,000+ open grants, or get matches ranked for your organization — free.
Focus Areas
Eligibility
How to Apply
Up to $421K
2031-02-28
- 1Confirm your organization is eligible for DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS from NIGMS - National Institute of General Medical Sciences, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIGMS - National Institute of General Medical Sciences before the deadline.
Don't want to draft it yourself?
We'll draft the complete application against NIGMS - National Institute of General Medical Sciences's requirements, run a quality review, and email you a submission-ready PDF plus an editable Word doc within 5 business days. Most orders deliver in 24-48 hours. Flat $399, any grant size.
AI Requirement Analysis
Detailed requirements not yet analyzed
Have the NOFO? Paste it below for AI-powered requirement analysis.
DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS: Frequently Asked Questions
Who is eligible for the DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS?
DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS is offered by NIGMS - National Institute of General Medical Sciences and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS provide?
DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS provides up to $421K per award from NIGMS - National Institute of General Medical Sciences. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS deadline?
Applications for DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS are due 2031-02-28 (open). Because deadlines can change, verify the date with the funder, NIGMS - National Institute of General Medical Sciences, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS?
To apply for DIRECTED EVOLUTION OF BIOCATALYSTS FOR ASYMMETRIC HYDROGEN ATOM TRANSFER REACTIONS, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIGMS - National Institute of General Medical Sciences.