Network-based models for continuous cell state inference
NIGMS - National Institute of General Medical Sciences
About This Grant
PROJECT SUMMARY/ABSTRACT The trillions of cells that make up the human body have vastly different identities and functions while, for the most part, sharing identical genomes and originating and differentiating from a single cell. Cells are typically grouped into discrete cell types reflecting, among other attributes, their tissue of origin and function. However, with the advent of technologies that operate at cellular and subcellular resolutions it has become increasingly clear that cells exist in a continuous range of dynamic states, particularly in the contexts of development and disease. Over the next five years, my research group will develop computational methods aimed at understanding the continuous nature of cell states. In particular, we will develop network-based models to integrate multiple modalities of large-scale genomics data with a focus on epigenetics and the noncoding genome. Some of the core questions we will examine are how the differences in measurements between modalities can be used to infer change over time, what role cell-cell communication and spatial organization play in determining cell state, and what are the genetic mechanisms that drive changes in cell state. I envision that, through this line of inquiry, we will be better able to identify potential druggable targets that play a role in determining cell state.
Grant Summary
Network-based models for continuous cell state inference is a NIGMS - National Institute of General Medical Sciences grant providing up to $434K for university, nonprofit, healthcare org. Applications are due 2031-02-28 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
How to Apply
Up to $434K
2031-02-28
- 1Confirm your organization is eligible for Network-based models for continuous cell state inference from NIGMS - National Institute of General Medical Sciences, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIGMS - National Institute of General Medical Sciences before the deadline.
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Network-based models for continuous cell state inference: Frequently Asked Questions
Who is eligible for the Network-based models for continuous cell state inference?
Network-based models for continuous cell state inference is offered by NIGMS - National Institute of General Medical Sciences and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Network-based models for continuous cell state inference provide?
Network-based models for continuous cell state inference provides up to $434K per award from NIGMS - National Institute of General Medical Sciences. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Network-based models for continuous cell state inference deadline?
Applications for Network-based models for continuous cell state inference are due 2031-02-28 (open). Because deadlines can change, verify the date with the funder, NIGMS - National Institute of General Medical Sciences, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Network-based models for continuous cell state inference?
To apply for Network-based models for continuous cell state inference, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIGMS - National Institute of General Medical Sciences.