Adaptation of a home blood pressure monitoring program for rural Mississippi
About This Grant
Project Summary/Abstract Mississippi (MS) is the poorest U.S. state with the lowest life expectancy and highest prevalence of hypertension (HTN). Rural individuals in MS additionally experience geographic and contextual factors that exacerbate chronic disease severity and their accompanying medical and social costs. The objective of this program is to conduct essential preparatory activities for a type 1 hybrid effectiveness-implementation trial to address and improve HTN in rural MS. We have developed and validated a program that includes theory- informed chronic disease self-management (CDSM) and incorporates: (1) longitudinal home blood pressure monitoring (HBPM), recognized as highly effective for patient engagement to improve self-efficacy and HTN management; and (2) a virtual agent, delivered by smartphone to provide an empathic, personalized CDSM curriculum. Our preliminary data demonstrate that the agent has high acceptability, enhances HBPM adherence, and contributes to 6-month reduction in systolic blood pressure (SBP). We have developed a Community Engagement Collaborative (CEC) to participate in the adaptation and evaluation of our CDSM program for HTN with the following aims: Aim 1. Modify the virtual agent intervention for application in rural MS. We will retain the agent’s primary objective to promote CDSM for HTN with routine HBPM and the secondary objectives to address health literacy, medication adherence, and non-pharmacologic approaches to HTN control. We will engage in an iterative, user-centered process that prioritizes the expertise and perspective of the target user. We will apply the results to rapid cycle adaptation of the agent to enhance its accessibility and usability and to evaluate novel gamification elements to support HBPM and agent use. Aim 2. Conduct a pilot evaluation to assess the effect of the intervention on SBP and HBPM adherence. We will enroll individuals with poorly controlled HTN (n=80) to receive a BP cuff and standardized instruction accompanied by 1:1 randomization with or without the virtual agent. As our primary outcome we will evaluate the effect of the HTN virtual agent on SBP at 6 months. As secondary outcomes we will evaluate (1) adherence to HBPM at 6 months and (2) the effect of the HTN virtual agent on SBP at 12 months. Aim 3. Evaluate the implementation process of the program with qualitative assessments of participants and primary care providers as guided by the Consolidated Framework for Implementation Research 2.0. We will conduct an explanatory sequential mixed methods design to identify potential mechanisms of effect of the program and its barriers, facilitators, and context. Expected results: Our multidisciplinary team in concert with our CEC has expertise in HBPM delivery, interventions for HTN, community engagement, and implementation. The proposed activities will adapt and evaluate a validated intervention to improve HTN control in individuals in rural MS. The results will enhance rigor, infrastructure, community engagement, and capacity to successfully conduct the proposed trial.
Grant Summary
Adaptation of a home blood pressure monitoring program for rural Mississippi is a NHLBI - National Heart Lung and Blood Institute grant providing up to $333K for university, nonprofit, healthcare org. Applications are due 2028-05-31 (open). Check eligibility and apply with FindGrants.
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Eligibility
How to Apply
Up to $333K
2028-05-31
- 1Confirm your organization is eligible for Adaptation of a home blood pressure monitoring program for rural Mississippi from NHLBI - National Heart Lung and Blood Institute, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NHLBI - National Heart Lung and Blood Institute before the deadline.
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Adaptation of a home blood pressure monitoring program for rural Mississippi: Frequently Asked Questions
Who is eligible for the Adaptation of a home blood pressure monitoring program for rural Mississippi?
Adaptation of a home blood pressure monitoring program for rural Mississippi is offered by NHLBI - National Heart Lung and Blood Institute and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Adaptation of a home blood pressure monitoring program for rural Mississippi provide?
Adaptation of a home blood pressure monitoring program for rural Mississippi provides up to $333K per award from NHLBI - National Heart Lung and Blood Institute. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Adaptation of a home blood pressure monitoring program for rural Mississippi deadline?
Applications for Adaptation of a home blood pressure monitoring program for rural Mississippi are due 2028-05-31 (open). Because deadlines can change, verify the date with the funder, NHLBI - National Heart Lung and Blood Institute, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Adaptation of a home blood pressure monitoring program for rural Mississippi?
To apply for Adaptation of a home blood pressure monitoring program for rural Mississippi, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NHLBI - National Heart Lung and Blood Institute.