Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use
About This Grant
PROJECT SUMMARY Background. Firefighters are repeatedly exposed to potentially traumatic events and many experience posttraumatic stress (PTS) symptoms as a result. Over 50% of firefighters report past-month heavy alcohol use and many use alcohol to “self-medicate” from symptoms of hyperarousal, intense negative affect, and insomnia that follow traumatic events. Transcutaneous auricular neurostimulation (tAN) of the vagus nerve has shown promise for alleviating symptoms of PTS and opioid withdrawal symptoms but its effects have yet to be tested in a sample of firefighters with alcohol use disorders (AUD) and co-occurring PTS symptoms. Aims. We will collaborate with a firefighter Community Advisory Board to develop a culturally informed, Phase II randomized clinical trial (RCT) protocol testing tAN as an intervention that may reduce PTS symptoms driving heavy alcohol use for firefighters with AUD (Aim 1; Year 1). We will then conduct a feasibility trial of the protocol (Aim 2; Year 2; N = 20) using the Sparrow device—a patient-administered, ear worn device that delivers electrical stimulation to branches of the vagus and trigeminal nerves—to evaluate the acceptability and feasibility of the protocol, and the appropriateness of the tAN intervention for firefighters with PTS/AUD. Using data from the feasibility study, we will complete an FDA pre-submission with the revised trial protocol to support a PTS/AUD indication for Sparrow Ascent, finalize the protocol with FDA feedback, and write an R01 application for a fully powered Phase II RCT (Aim 3; Year 3). Methods. The feasibility trial will recruit firefighters who engage in heavy drinking, have at least a mild AUD, and report above-average PTS symptoms. Participants will use the Sparrow device for at least 1 hour/day for 5 days/week throughout the 4-week treatment phase, but may use the device more often if they wish. Participants in the active tAN condition (n = 10) will receive therapeutic stimulation from Sparrow; active sham participants (n = 10) will feel stimulation at the trigeminal site only, but below a therapeutic level. They will complete daily measures of traumatic event exposure (number and type), PTS symptom severity, alcohol use (standard drinks) and motivations (trauma-related drinking), and audio journals capturing their experience with symptoms and the device (e.g., helpfulness). Additionally, wearable sensors will record heart rate, heart rate variability, and sleep data throughout the intervention phase. Assessments immediately following treatment (Week 4) and one month later (Week 8) will measure protocol feasibility and tAN’s clinical effects outcomes including insomnia, mental health symptoms, and quality of life. Outcomes. The primary feasibility outcome is the mean of protocol ratings on the Feasibility of Intervention Measure. Secondary feasibility outcomes include ratings of protocol acceptability (Acceptability of Intervention Measure) and Sparrow Ascent appropriateness (Intervention Appropriateness Measure). Exploratory clinical outcomes include reductions in PTS symptom severity scores and heavy drinking events.
Grant Summary
Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use is a NIAAA - National Institute on Alcohol Abuse and Alcoholism grant providing up to $228K for university, nonprofit, healthcare org. Applications are due 2029-04-30 (open). Check eligibility and apply with FindGrants.
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How to Apply
Up to $228K
2029-04-30
- 1Confirm your organization is eligible for Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use from NIAAA - National Institute on Alcohol Abuse and Alcoholism, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIAAA - National Institute on Alcohol Abuse and Alcoholism before the deadline.
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Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use: Frequently Asked Questions
Who is eligible for the Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use?
Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use is offered by NIAAA - National Institute on Alcohol Abuse and Alcoholism and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use provide?
Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use provides up to $228K per award from NIAAA - National Institute on Alcohol Abuse and Alcoholism. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use deadline?
Applications for Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use are due 2029-04-30 (open). Because deadlines can change, verify the date with the funder, NIAAA - National Institute on Alcohol Abuse and Alcoholism, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use?
To apply for Developing and Evaluating a Firefighter Self-Administered Neurostimulation Intervention for Traumatic Stress to Reduce Alcohol Use, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIAAA - National Institute on Alcohol Abuse and Alcoholism.