Differentiation and characteristics of Helios+ CD8+ T cells
NIAID - National Institute of Allergy and Infectious Diseases
About This Grant
Summary Regulation of immune responses is critical to provide beneficial immunity against pathogens and cancer, while avoiding autoimmune diseases and immunopathology. A population of memory-phenotype CD8+ T cells, expressing the transcription factor Helios” has been proposed to play a key role in preventing excessive and autoimmune responses following vaccination or infection. However, the precise identity of these Helios+ “regulatory” CD8+ T cells, the factors controlling their differentiation and maintenance, and the exact ways in which they contribute to immune homeostasis are highly controversial. In this exploratory proposal, we develop model systems intended to dissect the development, homeostasis and specificity of these CD8+ T cells, position ourselves for future studies on the physiological role and therapeutic potential of Helios+ CD8+ T cells.
Grant Summary
Differentiation and characteristics of Helios+ CD8+ T cells is a NIAID - National Institute of Allergy and Infectious Diseases grant providing up to $407K for university, nonprofit, healthcare org. Applications are due 2028-01-31 (open). Check eligibility and apply with FindGrants.
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Eligibility
How to Apply
Up to $407K
2028-01-31
- 1Confirm your organization is eligible for Differentiation and characteristics of Helios+ CD8+ T cells from NIAID - National Institute of Allergy and Infectious Diseases, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIAID - National Institute of Allergy and Infectious Diseases before the deadline.
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Differentiation and characteristics of Helios+ CD8+ T cells: Frequently Asked Questions
Who is eligible for the Differentiation and characteristics of Helios+ CD8+ T cells?
Differentiation and characteristics of Helios+ CD8+ T cells is offered by NIAID - National Institute of Allergy and Infectious Diseases and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Differentiation and characteristics of Helios+ CD8+ T cells provide?
Differentiation and characteristics of Helios+ CD8+ T cells provides up to $407K per award from NIAID - National Institute of Allergy and Infectious Diseases. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Differentiation and characteristics of Helios+ CD8+ T cells deadline?
Applications for Differentiation and characteristics of Helios+ CD8+ T cells are due 2028-01-31 (open). Because deadlines can change, verify the date with the funder, NIAID - National Institute of Allergy and Infectious Diseases, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Differentiation and characteristics of Helios+ CD8+ T cells?
To apply for Differentiation and characteristics of Helios+ CD8+ T cells, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIAID - National Institute of Allergy and Infectious Diseases.