Dietary regulation of sleep in a blood-feeding insect
NIAID - National Institute of Allergy and Infectious Diseases
About This Grant
Proposal Summary Neural regulation of sleep, appetite and energy homeostasis is critical to an animal’s survival and under stringent evolutionary pressure. Despite the prevalence of disorders associated with metabolism and sleep, the neural and genetic processes that regulate interactions between these two systems is unclear. This proposal will investigate how sleep is regulated by blood feeding in the disease vector mosquito Aedes aegypti. We will systematically define sleep in mosquitos, and determine the dietary amino acids that promote sleep. We will then screen neuropeptides for regulators of sleep to test for neuromodulators required for sleep following a blood meal. These experiments leverage decades of sleep analysis in fruit flies, to define sleep in a blood feeding insect. The findings have potential to identify conserved regulators of sleep-feeding interactions, as well as providing the first investigation of how macronutrients regulate sleep in a blood-feeding insect. Further, the methodology used to define sleep can be readily applied to other mosquito species. Therefore, the completion of this work will establish Ae. aegypti as a model for studying dietary regulation of sleep.
Grant Summary
Dietary regulation of sleep in a blood-feeding insect is a NIAID - National Institute of Allergy and Infectious Diseases grant providing up to $412K for university, nonprofit, healthcare org. Applications are due 2028-01-31 (open). Check eligibility and apply with FindGrants.
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How to Apply
Up to $412K
2028-01-31
- 1Confirm your organization is eligible for Dietary regulation of sleep in a blood-feeding insect from NIAID - National Institute of Allergy and Infectious Diseases, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIAID - National Institute of Allergy and Infectious Diseases before the deadline.
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Dietary regulation of sleep in a blood-feeding insect: Frequently Asked Questions
Who is eligible for the Dietary regulation of sleep in a blood-feeding insect?
Dietary regulation of sleep in a blood-feeding insect is offered by NIAID - National Institute of Allergy and Infectious Diseases and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Dietary regulation of sleep in a blood-feeding insect provide?
Dietary regulation of sleep in a blood-feeding insect provides up to $412K per award from NIAID - National Institute of Allergy and Infectious Diseases. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Dietary regulation of sleep in a blood-feeding insect deadline?
Applications for Dietary regulation of sleep in a blood-feeding insect are due 2028-01-31 (open). Because deadlines can change, verify the date with the funder, NIAID - National Institute of Allergy and Infectious Diseases, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Dietary regulation of sleep in a blood-feeding insect?
To apply for Dietary regulation of sleep in a blood-feeding insect, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIAID - National Institute of Allergy and Infectious Diseases.