Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD
NINDS - National Institute of Neurological Disorders and Stroke
About This Grant
Summary: Neuroimaging and histopathology represent two cornerstone methodologies in the study of age-related cognitive impairment and dementia, each offering unique and complementary insights into underlying disease mechanisms and therapeutic strategies. With the advancement of noninvasive imaging techniques aimed at probing the causal pathways and enabling robust early diagnosis of Alzheimer’s disease (AD) and AD–related dementias (ADRD), there is a growing need for postmortem validation studies to confirm the pathological underpinnings of early imaging biomarkers – particularly those related to vascular contributions to cognitive impairment and dementia (VCID). Although postmortem MRI has emerged as a valuable bridge between imaging and pathology, significant technical and methodological challenges persist. This workshop aims to foster the advancement and sharing of cutting-edge technologies, methodologies, and biomedical materials that bridge human neuropathology with neuroimaging research. By capitalizing on rare post-mortem data, the event seeks to deepen our understanding of the pathophysiological processes underlying imaging markers of AD/ADRD. We are requesting funds to support the “Tools and Resources to Understand Pathophysiology with Post-mortem Studies of in vivo Neuroimaging Findings in AD and ADRD” workshop which will take place on August 13-14, 2026, in New York University (NYU) Grossman School of Medicine, New York. The workshop has three specific aims. Aim 1: Bring together thought leaders and experts in the area of post-mortem AD research to advance the field and accelerate the pace of discovery; Aim 2: Foster career development in the field of neuroimaging and neuropathology of age-related dementias, supporting recruitment of new ideas and innovations in this uniquely growing research discipline; and Aim 3: Raise public awareness of and communicate the value of new tools, resources, and biomaterials of neuroimaging and neuropathology research in AD and ADRD to a broader audience. To achieve these aims, the program includes: (i) optimized protocols for postmortem imaging and histopathology; (ii) multidisciplinary topics—including forensic medicine—addressing postmortem interval (PMI) and fixation effects; (iii) daily presentations by Early Career Investigators and trainees selected from abstracts; (iv) new ideas and emerging leaders in VCID research from both in vivo and pathology perspectives at four dedicated panel discussions; (v) hands-on training and demonstrations of advanced tools developed across collaborative sites, including hemisphere imaging, multi- contrast/multi-scale registration, and proteomics; and (vi) shared access to pre- and postmortem MRI data and digital biomaterials for the research community. This unique workshop will serve as a vital forum for idea exchange, fostering new collaborations, and cultivating the next generation of postmortem researchers. Additionally, it aims to advance the translation of ex vivo findings into clinical diagnostics and therapeutic strategies that contribute to the prevention and treatment of Alzheimer’s disease.
Grant Summary
Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD is a NINDS - National Institute of Neurological Disorders and Stroke grant providing up to $20K for university, nonprofit, healthcare org. Applications are due 2027-04-30 (open). Check eligibility and apply with FindGrants.
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Up to $20K
2027-04-30
- 1Confirm your organization is eligible for Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD from NINDS - National Institute of Neurological Disorders and Stroke, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NINDS - National Institute of Neurological Disorders and Stroke before the deadline.
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Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD: Frequently Asked Questions
Who is eligible for the Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD?
Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD is offered by NINDS - National Institute of Neurological Disorders and Stroke and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD provide?
Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD provides up to $20K per award from NINDS - National Institute of Neurological Disorders and Stroke. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD deadline?
Applications for Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD are due 2027-04-30 (open). Because deadlines can change, verify the date with the funder, NINDS - National Institute of Neurological Disorders and Stroke, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD?
To apply for Tools and Resources to Understand Pathophysiology with Post-Mortem Studies of in vivo Neuroimaging Findings in AD and ADRD, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NINDS - National Institute of Neurological Disorders and Stroke.