Mitochondria Signaling in Physiology and Disease
NINDS - National Institute of Neurological Disorders and Stroke
About This Grant
Abstract Support is requested for a Keystone Symposia conference, “Mitochondria Signaling in Physiology and Disease,” organized by Drs. Navdeep S. Chandel and Aleksandra Trifunovic, with scientific programming input from Keystone Symposia. The meeting will take place February 9–12, 2026 at Keystone Resort in Keystone, Colorado. For decades, mitochondria were cast in the limited, yet essential role as powerhouses of the cell. In the past 25 years, this view has changed as mitochondria have emerged as a major signaling hub that dictates cellular fate and function to control cellular physiology. Aberrant mitochondrial signaling can cause diseases, which have historically been attributed to a lack of ATP within cells with mitochondrial dysfunctions. A novel conceptual framework for the role of mitochondria in cellular physiology has emerged, yet the mechanistic details of how mitochondrial signals dictate cell fate and function are not fully understood. While traditional views in the field emphasized impaired ATP production and increased oxidative stress as primary drivers of aging, recent research has highlighted additional mechanisms. These include the role of mitochondria-generated reactive oxygen species (ROS), metabolites, and mitochondrial DNA (mtDNA) as key signaling molecules that regulate inflammation, epigenetic modifications, and cellular stress responses, offering new insights into their contribution to primary mitochondrial diseases, autoimmunity, aging and neurogenerative diseases like Parkinson’s disease. This Keystone Symposia meeting aims to bring together a cross-disciplinary group of biologists, clinicians, and pharmaceutical scientists to broaden our basic understanding of the role of mitochondria as central signaling hubs in the cell, as well as address whether mitochondria can be targeted for a variety of diseases including inflammation and neurodegeneration, thereby reducing the burden of neurological disease. This meeting will support new collaborations geared toward improving disease-focused areas where mitochondria play critical roles. Attendees will also benefit from training workshops, panel discussions and a career roundtable, enhancing their skills and expertise in the field.
Grant Summary
Mitochondria Signaling in Physiology and Disease is a NINDS - National Institute of Neurological Disorders and Stroke grant providing up to $21K for university, nonprofit, healthcare org. Applications are due 2027-01-31 (open). Check eligibility and apply with FindGrants.
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How to Apply
Up to $21K
2027-01-31
- 1Confirm your organization is eligible for Mitochondria Signaling in Physiology and Disease from NINDS - National Institute of Neurological Disorders and Stroke, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NINDS - National Institute of Neurological Disorders and Stroke before the deadline.
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Mitochondria Signaling in Physiology and Disease: Frequently Asked Questions
Who is eligible for the Mitochondria Signaling in Physiology and Disease?
Mitochondria Signaling in Physiology and Disease is offered by NINDS - National Institute of Neurological Disorders and Stroke and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Mitochondria Signaling in Physiology and Disease provide?
Mitochondria Signaling in Physiology and Disease provides up to $21K per award from NINDS - National Institute of Neurological Disorders and Stroke. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Mitochondria Signaling in Physiology and Disease deadline?
Applications for Mitochondria Signaling in Physiology and Disease are due 2027-01-31 (open). Because deadlines can change, verify the date with the funder, NINDS - National Institute of Neurological Disorders and Stroke, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Mitochondria Signaling in Physiology and Disease?
To apply for Mitochondria Signaling in Physiology and Disease, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NINDS - National Institute of Neurological Disorders and Stroke.