Diabetes Prevention through Genetics, Familial History and Behavior Change
NIMHD - National Institute on Minority Health and Health Disparities
About This Grant
Type 2 diabetes (T2D) affects 38.4 million U.S. adults, with 97.6 million at risk due to prediabetes, and that burden concentrates in racially/ethnic families or those living in rural communities, or both. Diagnosed diabetes prevalence among Black/African American, Hispanic/Latino, and American Indian/Alaska Native adults is roughly 1.5-2 times that of non-Hispanic White adults, and prediabetes prevalence in rural communities exceeds urban communities by 17%. Although the Diabetes Prevention Program (DPP) effectively reduces T2D incidence, adherence is highly variable and remains the strongest predictor of outcomes. Current DPP delivery emphasizes the individual, overlooking the family context, which strongly influences behavior change. Family health history (FHH) increases T2D risk 2.5-4.5-fold and motivates preventive action, yet structured FHH collection and family participation have not been integrated into DPP interventions. Our central hypothesis is that embedding family engagement and FHH assessment into the DPP will improve adherence, weight loss, and glycemic outcomes. Specific Aim 1 will systematically adapt existing curricula to develop a 6-session family component integrating comprehensive FHH collection using the validated CDC My Family Health Portrait tool and personalized T2D risk communication, with mixed-methods formative testing among 40 index participants and family members across rural and urban sites. Specific Aim 2 will conduct a 2- arm randomized controlled trial with 200 index participants with prediabetes plus their family members, stratified by geographical location and block randomized to receive either adapted DPP with family components or standard DPP. Primary outcomes include weight loss percentage, HbA1c reduction, and session attendance rates at 6 and 12 months. Specific Aim 3 will evaluate family outcomes and mechanisms of change using the Actor-Partner Interdependence Model to test whether health improvements extend beyond index participants and identify moderators explaining variation in family-level outcomes. The impact of this project directly addresses adherence barriers by leveraging family context within a multilevel prevention framework consistent with NIMHD priorities. The expected outcome is a scalable, family-centered model that strengthens DPP impact and advances diabetes prevention across rural and urban populations.
Grant Summary
Diabetes Prevention through Genetics, Familial History and Behavior Change is a NIMHD - National Institute on Minority Health and Health Disparities grant providing up to $702K for university, nonprofit, healthcare org. Applications are due 2031-01-31 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $702K
2031-01-31
- 1Confirm your organization is eligible for Diabetes Prevention through Genetics, Familial History and Behavior Change from NIMHD - National Institute on Minority Health and Health Disparities, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIMHD - National Institute on Minority Health and Health Disparities before the deadline.
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Diabetes Prevention through Genetics, Familial History and Behavior Change: Frequently Asked Questions
Who is eligible for the Diabetes Prevention through Genetics, Familial History and Behavior Change?
Diabetes Prevention through Genetics, Familial History and Behavior Change is offered by NIMHD - National Institute on Minority Health and Health Disparities and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Diabetes Prevention through Genetics, Familial History and Behavior Change provide?
Diabetes Prevention through Genetics, Familial History and Behavior Change provides up to $702K per award from NIMHD - National Institute on Minority Health and Health Disparities. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Diabetes Prevention through Genetics, Familial History and Behavior Change deadline?
Applications for Diabetes Prevention through Genetics, Familial History and Behavior Change are due 2031-01-31 (open). Because deadlines can change, verify the date with the funder, NIMHD - National Institute on Minority Health and Health Disparities, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Diabetes Prevention through Genetics, Familial History and Behavior Change?
To apply for Diabetes Prevention through Genetics, Familial History and Behavior Change, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIMHD - National Institute on Minority Health and Health Disparities.