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Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study

NIAID - National Institute of Allergy and Infectious Diseases

open
OpenLast verified: 2026-06-19

About This Grant

Abstract Increasing HIV preexposure prophylaxis (PrEP) coverage in the United States has impacted the HIV epidemic, with states that have higher levels of PrEP coverage experiencing greater reductions in HIV transmission. Yet PrEP scale-up to date remains well below the levels recommended by CDC. Our team recently documented the critical nature of telemedicine PrEP (telePrEP) – one in five PrEP users in the United States is receiving PrEP from the largest telePrEP provider, which provides services at no out-of-pocket cost to all users. We propose MISTR+, a project that will seek to establish an evidence base for telehealth and improve health outcomes for the over 100,000 users of this service by (1) developing a series of low-touch interventions based on existing evidence and new data analyses of telePrEP electronic records data, (2) testing interventions, and (3) enhancing our understanding of intervention performance through machine learning and cost-effectiveness analyses that will inform intervention prioritization. We will test interventions, such as message content, with a series of rapid randomized, controlled trials (also called A/B testing), seeking to improve health outcomes of PrEP care initiation, retention, and re-engagement. In addition to developing nuanced information regarding what components of interventions produce positive health effects, interventions without additional costs per user that improve health outcomes (such as messaging) will be scaled to all MISTR users for an immediate societal prevention benefit.

Grant Summary

Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study is a NIAID - National Institute of Allergy and Infectious Diseases grant providing up to $1.3M for university, nonprofit, healthcare org. Applications are due 2031-05-31 (open). Check eligibility and apply with FindGrants.

Focus Areas

health research

Eligibility

universitynonprofithealthcare org

How to Apply

Funding Range

Up to $1.3M

Deadline

2031-05-31

Complexity
High
  1. 1Confirm your organization is eligible for Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study from NIAID - National Institute of Allergy and Infectious Diseases, checking organization type, location, and any population or project requirements.
  2. 2Gather the required documents and information, including your organization details, project plan, and budget figures.
  3. 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
  4. 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIAID - National Institute of Allergy and Infectious Diseases before the deadline.
This record is a past award, contract, or funder profile — useful for research, but not an open grant application. Check the original source for current opportunities from this funder.

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Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study: Frequently Asked Questions

Who is eligible for the Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study?

Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study is offered by NIAID - National Institute of Allergy and Infectious Diseases and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.

How much funding does the Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study provide?

Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study provides up to $1.3M per award from NIAID - National Institute of Allergy and Infectious Diseases. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.

When is the Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study deadline?

Applications for Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study are due 2031-05-31 (open). Because deadlines can change, verify the date with the funder, NIAID - National Institute of Allergy and Infectious Diseases, and give yourself enough time to prepare a complete, competitive application before the close date.

How do you apply for the Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study?

To apply for Improving telePrEP Initiation and retention Outcomes in the US: The MISTR+Study, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIAID - National Institute of Allergy and Infectious Diseases.

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