A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial
NIAID - National Institute of Allergy and Infectious Diseases
About This Grant
ABSTRACT Sexually transmitted infections (STIs) remain a significant public health challenge in the United States, disproportionately affecting adolescents and young adults aged 15–24. Comprehensive STI screening— including extra-genital and blood testing—remains underutilized, particularly in emergency departments (EDs), where over 19 million adolescents and young adults receive care annually. Barriers such as time constraints, provider discomfort, and workflow challenges contribute to missed opportunities for STI detection. Even when STI testing occurs, patients are rarely linked to ongoing sexual health services, including STI treatment completion and HIV preventive care, leading to high rates of reinfection and continued disease transmission. Innovative interventions that fit efficiently within the ED workflow and maximize appropriate STI testing are needed. Our multi-disciplinary team developed STIckER (STI ChecK in the ER), a user-informed, theory-based digital patient decision aid designed to facilitate shared decision-making and increase STI testing rates in EDs. In a randomized controlled trial, STIckER significantly increased STI testing rates, improved patient-provider communication, and enhanced ED experience ratings. However, real-world effectiveness and implementation across diverse ED settings remain unexplored. This multi-center R01 study will evaluate STIckER’s effectiveness and implementation across 13 pediatric and adult EDs using a cluster-randomized stepped wedge hybrid type 2 trial. The specific aims of the proposal are: (1) to evaluate the effectiveness of STIckER on STI testing (clinical outcomes) among adolescent and young adult ED patients in a cluster-randomized stepped wedge trial; (2) to measure implementation outcomes across ED sites among key stakeholders, and (3) to evaluate STIckER’s impact on follow-up and linkage to outpatient sexual healthcare services. By integrating scalable, digital, patient- centered approaches into routine ED workflows, STIckER has the potential to transform STI screening and improve long-term sexual health outcomes for adolescents and young adults nationwide.
Grant Summary
A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial is a NIAID - National Institute of Allergy and Infectious Diseases grant providing up to $872K for university, nonprofit, healthcare org. Applications are due 2031-03-31 (open). Check eligibility and apply with FindGrants.
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Eligibility
How to Apply
Up to $872K
2031-03-31
- 1Confirm your organization is eligible for A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial from NIAID - National Institute of Allergy and Infectious Diseases, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIAID - National Institute of Allergy and Infectious Diseases before the deadline.
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A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial: Frequently Asked Questions
Who is eligible for the A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial?
A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial is offered by NIAID - National Institute of Allergy and Infectious Diseases and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial provide?
A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial provides up to $872K per award from NIAID - National Institute of Allergy and Infectious Diseases. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial deadline?
Applications for A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial are due 2031-03-31 (open). Because deadlines can change, verify the date with the funder, NIAID - National Institute of Allergy and Infectious Diseases, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial?
To apply for A Cluster Randomized Stepped-Wedge Effectiveness-Implementation Trial of a Patient Decision Aid to Increase Sexually Transmitted Infection Testing in the Emergency Department: The STIckER Trial, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIAID - National Institute of Allergy and Infectious Diseases.