Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis
NCCIH - National Center for Complementary and Integrative Health
About This Grant
Project Summary/Abstract Chronic pain affects a large portion of people with multiple sclerosis (PwMS), impacting their daily activities and overall quality of life. Mindfulness-Based Cognitive Therapy (MBCT) has shown effectiveness in alleviating pain for people with MS; however, there is considerable variation in how individuals respond to treatment. Consistent home practice is hypothesized to be a key factor in producing therapeutic outcomes. However, mastering a new skill in treatment does not necessarily mean that it will translate to real-life situations, and a consistent barrier to treatment success occurs when individuals fail to practice mindfulness in daily life. As a result, there is a significant need to identify barriers and facilitators to mindfulness practice among people with MS undergoing MBCT for chronic pain. Recent advances in mobile technology allow investigators to examine these barriers in close to real time and provide adaptive and timely intervention. This K23 Career Development Award will provide the candidate training in intensive longitudinal and micro-randomized trial design and analysis, acquire proficiency in just-in-time adaptive intervention (JITAI) development, and enhance grantsmanship and scientific dissemination skills with a focus on developing a successful R01 application utilizing pilot data from this project. This new training will be leveraged to advance understanding and engagement in mindfulness practice among individuals with MS participating in MBCT for chronic pain in three integrated steps. Aim 1 will utilize ecological momentary assessment (EMA) to identify barriers and facilitators to mindfulness practice among 80 individuals with MS during 8-weeks of MBCT. Aim 2 will develop a JITAI informed by the EMA data to deliver personalized “nudges” promoting mindfulness practice during MBCT sessions. This phase will also incorporate human-centered design methods and feedback from PwMS to maximize feasibility. Aim 3 will use micro-randomized trial methodology (MRT) to optimize JITAI components and explore preliminary feasibility for 50 people with MS participating in MBCT. All aims will be supported by didactic, experiential, and mentored training in the fundamentals of clinical research through the Department of Rehabilitation Medicine at the University of Washington School of Medicine. Collectively the research and training aims of this project seek to inform and personalize the delivery of mindfulness-based interventions (MBIs) for chronic pain not only in people with MS but also in other populations experiencing pain. This award will equip the candidate with the expertise to independently lead innovative research in MBIs, advance pain management strategies and enhance quality of life for individuals with chronic health conditions.
Grant Summary
Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis is a NCCIH - National Center for Complementary and Integrative Health grant providing up to $164K for university, nonprofit, healthcare org. Applications are due 2031-03-31 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $164K
2031-03-31
- 1Confirm your organization is eligible for Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis from NCCIH - National Center for Complementary and Integrative Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NCCIH - National Center for Complementary and Integrative Health before the deadline.
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Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis: Frequently Asked Questions
Who is eligible for the Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis?
Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis is offered by NCCIH - National Center for Complementary and Integrative Health and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis provide?
Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis provides up to $164K per award from NCCIH - National Center for Complementary and Integrative Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis deadline?
Applications for Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis are due 2031-03-31 (open). Because deadlines can change, verify the date with the funder, NCCIH - National Center for Complementary and Integrative Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis?
To apply for Optimizing Mindfulness Practice for Pain in People with Multiple Sclerosis, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NCCIH - National Center for Complementary and Integrative Health.