Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation.
NIMH - National Institute of Mental Health
About This Grant
PROJECT SUMMARY Cognitive flexibility refers to our capacity to adjust our behavior in response to changes in the environment or in our own internal states. Psychiatric disorders often disrupt these cognitive functions, but little is known about the patterns of activity in the brain that underlie these capacities, impeding the development of effective treatments to target them. The overarching goal of this project is to more clearly elucidate the specific neural activity patterns supporting three examples of cognitive flexibility: switching between sets of rules that guide our behavior in a given situation, making correct decisions in new situations by drawing on past experiences, and learning to rapidly adjust a previously learned rule. In this project, I have developed a behavioral task which can engage each of these behaviors. I will use high- channel count electrophysiological methods to record activity from a brain circuit spanning the hippocampus, prefrontal cortex, and motor output regions while non-human primates perform this task. I will test the hypothesis that specific features of the patterns of activity in these brain regions support each type of cognitive flexibility described above. The results of this project will contribute an important step towards developing more effective treatments for cognitive dysfunction by identifying the specific patterns of activity that support specific cognitive functions and behaviors. This project will provide the additional training I require to position myself to perform cutting-edge research on cognition as an independent investigator. Specifically, through this project I will learn to perform precisely anatomically-targeted, high-channel count electrophysiological recordings from multiple brain regions simultaneously in order to probe brain activity patterns relevant to behavior as they occur in real time, distributed across the brain. I will also develop the necessary expertise to analyze the activity of large populations of neurons in relation to complex behavior. This award is thus critical to attaining my long-term goal of running an independent research lab at an academic medical center, where I will operate a non-human primate electrophysiology lab studying the neural mechanisms of adaptive, flexible behaviors that are disrupted in psychiatric disorders.
Grant Summary
Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. is a NIMH - National Institute of Mental Health grant providing up to $194K for university, nonprofit, healthcare org. Applications are due 2031-05-17 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
How to Apply
Up to $194K
2031-05-17
- 1Confirm your organization is eligible for Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. from NIMH - National Institute of Mental Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIMH - National Institute of Mental Health before the deadline.
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Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation.: Frequently Asked Questions
Who is eligible for the Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation.?
Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. is offered by NIMH - National Institute of Mental Health and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. provide?
Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. provides up to $194K per award from NIMH - National Institute of Mental Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. deadline?
Applications for Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation. are due 2031-05-17 (open). Because deadlines can change, verify the date with the funder, NIMH - National Institute of Mental Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation.?
To apply for Elucidating the representational geometries underlying deductive reasoning, generalization, and flexible response generation., confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIMH - National Institute of Mental Health.