Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence
About This Grant
PROJECT SUMMARY/ABSTRACT Epidemiological research suggests that up to 20% of adolescents have experienced at least one episode of major depressive disorder (MDD) in their lives and that rates of depression among this group are increasing. To address this, research is needed to identify modifiable risk factors that can be targeted to reduce risk of depression in this age group. There is growing evidence that sleep disturbance is both a symptom of, and risk factor for, depression in adolescents. Across studies, there is support for decreased sleep duration, worse sleep quality, delayed sleep timing, and decreased sleep regularity prospectively predicting depressive symptoms among adolescents. What remains unclear are the mechanisms by which sleep disruptions might increase depression risk in adolescents. One promising potential mechanism of risk is the impact on adolescents’ ability to inhibit attention to depression-relevant stimuli. Although no studies have tested this specifically, there is clear evidence that sleep disruption and depression risk are both associated with related constructs including higher levels of repetitive negative thinking and rumination, as well as biases in attention toward depression-relevant stimuli. The proposed study will provide a fine-grained examination of links between specific forms of sleep disruption, measured via actigraphy and self-report measures, and deficits in adolescents’ ability to inhibit attention to depression-relevant stimuli, directly assessed via steady-state visually evoked potentials (ssVEPS) derived from encephalography (EEG). Primary Aim 1 is to determine whether indices of sleep disruption (sleep duration, timing, quality, and regularity) are related to deficits in adolescents’ ability to inhibit attention to negative (depression-relevant) stimuli and predict depressive symptom trajectories across a two-month follow-up. Primary Aim 2 is to determine whether difficulty inhibiting attention to depression-relevant stimuli predicts prospective changes in adolescents’ depressive symptoms. A secondary aim of this study is to evaluate whether difficulty inhibiting attention to depression-relevant stimuli statistically mediates the relation between specific indices of sleep disruption (duration, timing, quality, regularity) and changes in depression over the follow-up. These research aims are complemented by a series of training goals designed to facilitate the applicant’s development into an independent researcher. These training goals are to (i) gain specialized training in adolescent sleep research, (ii) gain expertise in collecting, processing, and analyzing ssVEP data, and (iii) strengthen knowledge of statistical methods for analyzing multi-wave longitudinal data. Overall, this study will provide a fine-grained, multi-method examination of sleep disruption and adolescent depression risk focused on a core mechanism of risk hypothesized to be impacted by the changes in sleep that often occur during adolescence. This study will also provide the training necessary for the applicant to become an independent researcher focused on risk for depression in adolescents.
Grant Summary
Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence is a NIMH - National Institute of Mental Health grant providing up to $35K for university, nonprofit, healthcare org. Applications are due 2028-07-26 (open). Check eligibility and apply with FindGrants.
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How to Apply
Up to $35K
2028-07-26
- 1Confirm your organization is eligible for Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence from NIMH - National Institute of Mental Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIMH - National Institute of Mental Health before the deadline.
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Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence: Frequently Asked Questions
Who is eligible for the Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence?
Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence is offered by NIMH - National Institute of Mental Health and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence provide?
Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence provides up to $35K per award from NIMH - National Institute of Mental Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence deadline?
Applications for Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence are due 2028-07-26 (open). Because deadlines can change, verify the date with the funder, NIMH - National Institute of Mental Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence?
To apply for Sleep Disruption, Difficulties Inhibiting Attention to Negative Stimuli, and Risk for Depression in Adolescence, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIMH - National Institute of Mental Health.