The Development of an early detection tool for oral-dental radiation induced injury
NIDCR - National Institute of Dental and Craniofacial Research
About This Grant
Osteoradionecrosis (ORN) of the jaw is a severe complication of radiotherapy (RT) in head and neck cancer patients, leading to significant oral dysfunction and compromised quality of life. Early detection is critical for timely intervention, yet current clinical methods often fail to identify ORN before irreversible damage occurs. This F31 project leverages Al-powered radiographic analysis to enhance ORN detection and management by developing predictive models and automated tools to assist clinicians. In Specific Aim 1, I will establish a clinical benchmark by evaluating the consistency of clinician assessments of radiographic ORN. This benchmark will provide a gold standard for comparison with Al-based models. Specific Aim 2 will focus on developing an automated segmentation tool to segment ORN on radiographic images, using physician-generated contours as the ground truth. Specific Aim 3 involves building a predictive model based on radiographic density changes {delta-HU) to identify patients at higher risk of ORN early in the treatment process. The training goals of this award will provide me with essential sills in Al model development, medical imaging techniques, and clinical decision support tools, all within the specialized field of radiation oncology. Through mentorship at MD Anderson Cancer Center, an internationally recognized leader in cancer treatment and research, I will gain the expertise necessary to translate these innovations into clinical practice. This research aligns with the mission of NIDCR by advancing technology that reduces radiation induced oral morbidities, ultimately improving patient outcomes in dental and oral health related to radiotherapy.
Grant Summary
The Development of an early detection tool for oral-dental radiation induced injury is a NIDCR - National Institute of Dental and Craniofacial Research grant providing up to $39K for university, nonprofit, healthcare org. Applications are due 2029-01-31 (open). Check eligibility and apply with FindGrants.
Focus Areas
Eligibility
How to Apply
Up to $39K
2029-01-31
- 1Confirm your organization is eligible for The Development of an early detection tool for oral-dental radiation induced injury from NIDCR - National Institute of Dental and Craniofacial Research, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to NIDCR - National Institute of Dental and Craniofacial Research before the deadline.
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The Development of an early detection tool for oral-dental radiation induced injury: Frequently Asked Questions
Who is eligible for the The Development of an early detection tool for oral-dental radiation induced injury?
The Development of an early detection tool for oral-dental radiation induced injury is offered by NIDCR - National Institute of Dental and Craniofacial Research and is generally open to university, nonprofit, healthcare org. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the The Development of an early detection tool for oral-dental radiation induced injury provide?
The Development of an early detection tool for oral-dental radiation induced injury provides up to $39K per award from NIDCR - National Institute of Dental and Craniofacial Research. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the The Development of an early detection tool for oral-dental radiation induced injury deadline?
Applications for The Development of an early detection tool for oral-dental radiation induced injury are due 2029-01-31 (open). Because deadlines can change, verify the date with the funder, NIDCR - National Institute of Dental and Craniofacial Research, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the The Development of an early detection tool for oral-dental radiation induced injury?
To apply for The Development of an early detection tool for oral-dental radiation induced injury, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from NIDCR - National Institute of Dental and Craniofacial Research.