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View full policyBlueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development
About This Grant
The NIH Blueprint for Neuroscience Research is interested in continuing to support the BluePrint Neurotherapeutics Network for Small Molecules (BPN-SM)- a program designed to help investigators advance promising small-molecule therapeutics toward clinical testing. The BPN-SM program supports drug discovery and development activities in investigators own laboratories while also providing access to NIH-supported subject matter experts and contract research organizations (CROs) with capabilities in medicinal chemistry, pharmacokinetics, toxicology, formulation development, GMP synthesis, and Phase I clinical testing. By integrating NIH resources with industry-standard expertise, BPN-SM advances investigator-initiated drug discovery while enabling investigators to retain and strengthen their intellectual property while gaining hands-on experience in translational drug development.The overarching goal of the program is to reduce the risk of scientific and therapy development sufficiently to enable external partners to take on late-stage development and ultimately bring new therapies to patients. In addition, this BPN program is specifically focused on small molecules and excludes biologics, because development, regulatory, and manufacturing considerations for each class of therapeutics differ substantially from each other. It will use a phased cooperative agreement mechanism which will enable the program to support innovative but higher-risk projects, with decisions of continued support being contingent on demonstrated feasibility of yearly milestones. A cooperative agreement framework is proposed because several key aspects of the program will involve collaborative activities between the investigators and NIH program staff, with substantial involvement beyond the normal scope of grant stewardship. The project principal investigator(s) and NIH program staff will work jointly with NIH-supported subject matter experts to coordinate and participate in all scientific and technical management aspects of the project.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop competitive projects and establish the cross-disciplinary collaborations necessary for success.
Grant Summary
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development is a National Institutes of Health grant providing funding that varies by award for municipality. Applications are due 2027-06-16 (open). Check eligibility and apply with FindGrants.
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Focus Areas
Eligibility
How to Apply
Up to $0K
2027-06-16
- 1Confirm your organization is eligible for Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development from National Institutes of Health, checking organization type, location, and any population or project requirements.
- 2Gather the required documents and information, including your organization details, project plan, and budget figures.
- 3Draft your application narrative and budget addressing the funder's priorities and review criteria. FindGrants can draft each section for you to review and edit.
- 4Review every section against the requirements checklist, then export a submission-ready application pack and submit it to National Institutes of Health before the deadline.
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Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development: Frequently Asked Questions
Who is eligible for the Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development?
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development is offered by National Institutes of Health and is generally open to municipality. It is open to organizations nationwide unless the funder specifies otherwise. Review the specific eligibility terms before applying, since funders set their own requirements around organization type, location, and the population or project being served.
How much funding does the Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development provide?
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development provides an amount that varies by award per award from National Institutes of Health. Actual award sizes depend on the scope of your project, available program funds, and the number of applicants, so build a budget that reflects realistic, allowable costs rather than the maximum figure.
When is the Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development deadline?
Applications for Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development are due 2027-06-16 (open). Because deadlines can change, verify the date with the funder, National Institutes of Health, and give yourself enough time to prepare a complete, competitive application before the close date.
How do you apply for the Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development?
To apply for Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development, confirm your eligibility, gather the required documents, and prepare a narrative and budget that address the funder's priorities. FindGrants guides you step by step and can draft each section, then exports a submission-ready application pack for this grant from National Institutes of Health.